Patents by Inventor David J. Kahler

David J. Kahler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS
    Publication number: 20110306516
    Abstract: The invention provides improved methods for producing induced pluripotent stem cells (iPSC) from adult fibroblasts. The methods include contacting adult fibroblasts with a reprogramming composition suitable for reprogramming the adult fibroblasts to iPSC, under conditions effective for the reprogramming composition to penetrate the adult fibroblasts, followed by culturing the contacted fibroblasts for a time period sufficient for the cells to be reprogrammed. The cultured cells are then sorted to select cells based upon their expression of the cell membrane surface markers CD13NEG SSEA4POS Tra-1-60POS. iPSC colonies are then identified from the sorted cells.
    Type: Application
    Filed: June 13, 2011
    Publication date: December 15, 2011
    Applicant: THE NEW YORK STEM CELL FOUNDATION
    Inventors: David J. Kahler, Faizzan S. Ahmad