Patents by Inventor David J. Lauffer

David J. Lauffer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azabicyclo oxime and amine cholinergic agents and methods of treatment
    Patent number: 5464842
    Abstract: Pharmaceutically useful nitrogen containing cyclic oxime and amine substituted compounds of the formulas I to XVI are disclosed (See specification for definitions of the substituents). Specifically, the compounds are 1-azabicyclo [3.2.1]oximes, 1-azabicyclo[3.3.1]oximes, 1-aza-4-oxobicyclo[3.3.1]oximes, 1-aza-4-oxobicyclo[3.2.
    Type: Grant
    Filed: March 3, 1994
    Date of Patent: November 7, 1995
    Assignee: Warner-Lambert Company
    Inventors: David J. Lauffer, Haile Tecle
  • Azabicyclo and azacyclo oxime and amine cholinergic agents and methods of treatment
    Patent number: 5346911
    Abstract: Pharmaceutically useful nitrogen containing cyclic oxime and amine substituted compounds which are azabicyclo[2.2.1]oximes, azabicyclo[2.2.2]oximes, azabicyclo[2.2.1]amines, azabicyclo[2.2.2]amines, azabicyclo[3.2.1]oximes, and amine containing heterocyclic oximes wherein the heterocyclic ring contains from 3 to 7 carbon atoms are disclosed.
    Type: Grant
    Filed: August 24, 1993
    Date of Patent: September 13, 1994
    Assignee: Warner-Lambert Company
    Inventors: Corinne E. Augelli-Szafran, Stephen D. Barrett, Bradley W. Caprathe, Adam A. Galan, Juan C. Jaen, David J. Lauffer, Walter H. Moos, Michael R. Pavia, Kathryn B. Sanders, Haile Tecle, Anthony J. Thomas
  • Azabicyclo oxime and amine cholinergic agents and methods of treatment
    Patent number: 5318978
    Abstract: Pharmaceutically useful nitrogen containing cyclic oxime and amine substituted compounds of the formulas I to XVI are disclosed (See specification for definitions of the substituents). Specifically, the compounds are 1-azabicyclo [3.2.1] oximes, 1-azabicyclo [3.3.1] oximes, 1-aza-4-oxobicyclo [3.3.1] oximes, 1-aza-4-oxobicyclo [3.2.
    Type: Grant
    Filed: January 5, 1993
    Date of Patent: June 7, 1994
    Assignee: Warner-Lambert Company
    Inventors: David J. Lauffer, Haile Tecle
  • Oxime and amine substituted azabicyclo and azocyclo muscarinic agonists and methods of treatment
    Patent number: 5306718
    Abstract: Pharmaceutically useful nitrogen containing cyclic oxime and amine substituted compounds of the following general Formulas I, II and III are disclosed: ##STR1## Specifically the compounds are azabicyclo [2.2.1] omimes, azabicyclo [2.2.2] oximes, azabicyclo [2.2.1] amines, azabicyclo [2.2.2] amines, azabicyclo [3.2.1] oximes and amine containing heterocyclic oximes wherein the heterocyclic ring contains from 4 to 5 [3 to 7] carbon atoms.
    Type: Grant
    Filed: October 16, 1991
    Date of Patent: April 26, 1994
    Assignee: Warner-Lambert Company
    Inventors: David J. Lauffer, Walter H. Moos, Michael R. Pavia, Haile Tecle, Anthony J. Thomas
  • Azabicycloalkane oxime & azabicycloalkene oxime muscarinic agents
    Patent number: 4937239
    Abstract: Novel 1-azabicycloalkane- and alkene-oximes (Ia) and 8-azabicyclo[3.2.1]octane- and octene-oximes (Ib) are provided, these compounds being useful as agents for treating pain or for treating the symptoms of senile cognitive decline. Also provided are pharmaceutical compositions containing the compounds and methods of treatment using the compounds in dosage form.
    Type: Grant
    Filed: February 13, 1989
    Date of Patent: June 26, 1990
    Assignee: Warner-Lambert Company
    Inventors: David J. Lauffer, Walter H. Moos, Hasile Tecle