Abstract: A vascular introducer hub has a body that includes a proximal end, a distal end, and a lumen defined therethrough. The hub includes first and second seals disposed within the body. The first seal includes a first polymeric material and the second seal includes a second polymeric material. The hub is characterized by the first and second polymeric materials having different durometers.

Abstract: A heart valve anchor has a body that includes a distal portion, a distal end, a proximal portion, and a proximal end. The distal end and the proximal end define a longitudinal axis. The body has an expandable portion that includes a first radially expandable portion at the distal portion of the body, a second radially expandable portion at the proximal portion of the body, and a root portion disposed between the first and second radially expandable portions. The body has a first configuration adapted to be housed at least partially within a tissue penetrating device, and a second configuration in which the first and second radially expandable portions are partially or fully expanded such that the anchor engages tissue in a region between the first and second radially expandable portions.

Abstract: An introducer catheter device comprising a handle and an elongate shaft coupled to the handle and extending therefrom. The shaft defines a lumen therethrough, a longitudinal axis, and a first aperture in connection with the lumen. The shaft includes a movable deployment element configured for deploying an ancillary device from the first aperture at an angle relative to the longitudinal axis.

Abstract: Tissue regions are treated using a multiple lead electrode probe. A plurality of electrodes may be disposed about an elongate shaft. The elongate shaft may be slidably disposed within a lumen of a delivery sheath. One or more probes including one or more electrically active regions may also be slidably disposed within the delivery sheath. The one or more probes may be configured to extend radially about the elongate shaft. The plurality of electrodes and the electrically active regions may be individually connected to a control and power unit through individual channels.

Abstract: A heart valve anchor has a body that includes a distal portion, a distal end, a proximal portion, and a proximal end. The distal end and the proximal end define a longitudinal axis. The body has an expandable portion that includes a first radially expandable portion at the distal portion of the body, a second radially expandable portion at the proximal portion of the body, and a root portion disposed between the first and second radially expandable portions. The body has a first configuration adapted to be housed at least partially within a tissue penetrating device, and a second configuration in which the first and second radially expandable portions are partially or fully expanded such that the anchor engages tissue in a region between the first and second radially expandable portions.

Abstract: A vascular introducer hub has a body that includes a proximal end, a distal end, and a lumen defined therethrough. The hub includes first and second seals disposed within the body. The first seal includes a first polymeric material and the second seal includes a second polymeric material. The hub is characterized by the first and second polymeric materials having different durometers.

Abstract: An introducer catheter device comprising a handle and an elongate shaft coupled to the handle and extending therefrom. The shaft defines a lumen therethrough, a longitudinal axis, and a first aperture in connection with the lumen. The shaft includes a movable deployment element configured for deploying an ancillary device from the first aperture at an angle relative to the longitudinal axis.

Abstract: Tissue regions are treated using a multiple lead electrode probe. A plurality of electrodes may be disposed about an elongate shaft. The elongate shaft may be slidably disposed within a lumen of a delivery sheath. One or more probes including one or more electrically active regions may also be slidably disposed within the delivery sheath. The one or more probes may be configured to extend radially about the elongate shaft. The plurality of electrodes and the electrically active regions may be individually connected to a control and power unit through individual channels.

Abstract: This document provides medical device systems and methods for obtaining tissue samples. For example, this document provides medical device systems and methods for transbronchial needle biopsy tissue acquisition. In some cases, a needle biopsy system includes an actuator device, an outer needle with a lumen therethrough, and an inner needle at least partially disposed within the lumen. The outer needle can extend distally from the actuator device. A distal tip of the inner needle can be capable of being fully disposed within the lumen. The inner needle can extend distally from the actuator device. The actuator device can be configured to translate the outer needle proximally and distally. The actuator device can be configured to translate the inner needle proximally and distally independently of the outer needle.

Abstract: An inclination indicating apparatus having a housing with a base defining a first plane. A plurality of support legs support the base of the housing above the surface in an operational configuration. At least one of the support legs is rotatable so that a bottom portion of the at least one support leg traverses a second plane parallel to the first plane from the operational configuration to a storage configuration. A circular float level mounted on the housing having a bubble indicator provides an indication the slope of the first plane relative to the surface.

Abstract: A lightweight, freestanding modular changing room system which can be assembled using few or no tools. The modular freestanding changing room system may consist of as few as four unique components--interchangeable wall panels, door panel assemblies, and two types of panel support columns. Additional components may be added to create more elaborate changing room configurations.