Patents by Inventor David J. Loskutoff

David J. Loskutoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic Peptides Derived from Urokinase Plasminogen Activator Receptor
    Publication number: 20080280833
    Abstract: The present invention relates to a chemotactically active epitope derivable from the urokinase receptor, a mutated peptide that acts as an inhibitor of chemotaxis, and their therapeutic use.
    Type: Application
    Filed: January 31, 2006
    Publication date: November 13, 2008
    Inventors: Bernard Degryse, Massimo Resnati, Ralf-Peter Czekay, David J. Loskutoff, Francesco Blasi
  • Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators and gene coding for the inhibitor
    Patent number: 6103876
    Abstract: A biological reagent and diagnostic system for the detection and quantitation of endothelial plasminogen activator inhibitor (PAI) are disclosed, as are substantially pure, recombinant human endothelial PAI, its biologically pure gene and a vector for cloning the gene and expressing a gene product.
    Type: Grant
    Filed: May 13, 1997
    Date of Patent: August 15, 2000
    Assignee: The Scripps Research Institute
    Inventors: David J. Loskutoff, Tor Ny, Michael Sawdey
  • Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators, and gene coding for the inhibitor
    Patent number: 5629160
    Abstract: A biological reagent and diagnostic system for the detection and quantitation of endothelial plasminogen activator inhibitor (PAI) are disclosed, as are substantially pure, recombinant human endothelial PAI, its biologically pure gene and a vector for cloning the gene and expressing a gene product.
    Type: Grant
    Filed: May 24, 1994
    Date of Patent: May 13, 1997
    Assignee: The Scripps Clinic and Research Foundation
    Inventors: David J. Loskutoff, Tor Ny, Michael Sawdey
  • Inhibitor of tissue-type and urokinase-type plasminogen activators
    Patent number: 5314994
    Abstract: A biological reagent and diagnostic system for the detection and quantitation of endothelial plasminogen activator inhibitor (PAI) are disclosed, as are substantially pure, recombinant human endothelial PAI, its biologically pure gene and a vector for cloning the gene and expressing a gene product.
    Type: Grant
    Filed: April 29, 1992
    Date of Patent: May 24, 1994
    Assignee: Scripps Clinic and Research Foundation
    Inventors: David J. Loskutoff, Tor Ny, Michael Sawdey
  • Gene encoding an inhibitor of tissue-type and urokinase-type plasminogen activators
    Patent number: 4952512
    Abstract: A biological reagent and diagnostic system for the detection and quantitation of endothelial plasminogen activator inhibitor (PAI) are disclosed, as are substantially pure, recombinant human endothelial PAI, its biologically pure gene and a vector for cloning the gene and expressing a gene product.
    Type: Grant
    Filed: August 19, 1986
    Date of Patent: August 28, 1990
    Inventors: David J. Loskutoff, Tor Ny, Michael Sawdey
  • Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators
    Patent number: 4791068
    Abstract: A biochemical reagent system and methods for preparing and using same, as well as diagnostics utilizing the reagent system are disclosed. The biochemical reagent system comprises a receptor raised in an animal host to plasminogen activator inhibitor, and indicating means. The receptor binds to a specific plasminogen activator inhibitor that itself binds to tissue-type or urokinase-type plasminogen activators.
    Type: Grant
    Filed: June 22, 1984
    Date of Patent: December 13, 1988
    Assignee: Scripps Clinic and Research Foundation
    Inventors: David J. Loskutoff, Raymond R. Schleef