Patents by Inventor David J. Nisbet
David J. Nisbet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160347861Abstract: Methods for reducing the amount of ruminal saturation of unsaturated fatty acids and poly-unsaturated fatty acids in a ruminant by administering compositions that interfere and reduce lipolysis and/or biohydrogenation are provided. In one embodiment, the composition is antibodies that bind to immunogens involved in lipolysis and/or biohydrogenation. In another embodiment, the composition is an immunogenic composition containing immunogens involved in lipolysis and/or biohydrogenation. Method for producing the antibodies are also provided.Type: ApplicationFiled: May 23, 2016Publication date: December 1, 2016Inventors: Robin C Anderson, David J. Nisbet, Holly D. Edwards
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Patent number: 7176244Abstract: The invention provides a method and compositions for controlling food borne enteric bacterial pathogens in animals. Populations of enteropathogenic bacteria may be substantially reduced or eliminated by treatment of animals with an effective amount of 2-nitropropanol, 2-nitroethane or 2-nitroethanol. The compounds may be administered orally, providing a reduction in the populations of the enteropathogenic bacteria in the alimentary tract of the animal, or they may be applied externally onto the animal to reduce the populations of any such bacteria which may be present as contaminants on the surface of the animal. The method and compositions are particularly useful for the control of Salmonella species, enteropathogenic Escherichia coli, Campylobacter species, and Listeria monocytogenes.Type: GrantFiled: December 16, 2002Date of Patent: February 13, 2007Assignee: The United States of America as represented by the Secretary of AgricultureInventors: Robin C. Anderson, David J. Nisbet, Yong Soo Jung
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Patent number: 6761911Abstract: The invention provides a method and compositions for controlling food borne enteric bacterial pathogens in animals. Populations of enteropathogenic bacteria may be substantially reduced or eliminated by treatment of animals with an effective amount of the compound Xm(ClO3)n, wherein X is a cationic moiety and m and n are independently selected from integers necessary to provide a net valency of 0. The compounds may be administered orally, providing a reduction in the populations of the enteropathogenic bacteria in the alimentary tract of the animal, or they may be applied externally onto the animal to reduce the populations of any such bacteria which may be present as contaminants on the surface of the animal. The method and compositions are particularly useful for the control of Salmonella species, enteropathogenic Escherichia coli, and Clostridia species.Type: GrantFiled: October 3, 2002Date of Patent: July 13, 2004Assignee: The United States of America as represented by the Secretary of AgricultureInventors: Robin C. Anderson, David J. Nisbet, Larry H. Stanker
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Patent number: 6670374Abstract: The invention provides a method for treating infections in animals which are caused by toxin-producing enteric bacterial pathogens, including Shigella species, enterohemorrhagic E. coli, and enterotoxigenic E. coli. Receptors expressed by animal cells which typically recognize these bacterial toxins may be modified by administration of swainsonine compounds to the animal, thereby effectively inhibiting toxin binding to the cells.Type: GrantFiled: June 11, 2002Date of Patent: December 30, 2003Assignee: The United States of America as represented by the Secretary of AgricultureInventors: Robin C. Anderson, David J. Nisbet, Robert E. Droleskey
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Publication number: 20030039703Abstract: The invention provides a method and compositions for controlling food borne enteric bacterial pathogens in animals. Populations of enteropathogenic bacteria may be substantially reduced or eliminated by treatment of animals with an effective amount of the compound Xm(ClO3)n, wherein X is a cationic moiety and m and n are independently selected from integers necessary to provide a net valency of 0. The compounds may be administered orally, providing a reduction in the populations of the enteropathogenic bacteria in the alimentary tract of the animal, or they may be applied externally onto the animal to reduce the populations of any such bacteria which may be present as contaminants on the surface of the animal. The method and compositions are particularly useful for the control of Salmonella species, enteropathogenic Escherichia coli, and Clostridia species.Type: ApplicationFiled: October 3, 2002Publication date: February 27, 2003Applicant: The United States of America,as represented by the Secretary of AgricultureInventors: Robin C. Anderson, David J. Nisbet, Larry H. Stanker
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Patent number: 6475527Abstract: The invention provides a method and compositions for controlling food borne enteric bacterial pathogens in animals. Populations of enteropathogenic bacteria may be substantially reduced or eliminated by treatment of animals with an effective amount of the compound Xm(ClO3)n, wherein X is a cationic moiety and m and n are independently selected from integers necessary to provide a net valency of 0. The compounds may be administered orally, providing a reduction in the populations of the enteropathogenic bacteria in the alimentary tract of the animal, or they may be applied externally onto the animal to reduce the populations of any such bacteria which may be present as contaminants on the surface of the animal. The method and compositions are particularly useful for the control of Salmonella species, enteropathogenic Escherichia coli, and Clostridia species.Type: GrantFiled: July 15, 1999Date of Patent: November 5, 2002Assignee: The United States of America as represented by the Secretary of AgricultureInventors: Robin C. Anderson, David J. Nisbet, Larry H. Stanker
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Patent number: 5951977Abstract: A defined probiotic or composition of anaerobic bacteria effective for controlling or inhibiting Salmonella colonization of swine is disclosed. The probiotic includes populations or cultures of substantially biologically pure bacteria which include:Enterococcus faecalis,Streptococcus bovis,Clostridium clostridiforme,Clostridium symbiosum,Clostridium ramosum,Bacteroides fragilis,Bacteroides distasonis,Bacteroides vulgatus,Bacteroides thetaiotamicron, andBacteroides caccae.In use, the probiotic is administered to the subject swine in an amount effective for increasing resistance to Salmonella colonization thereof.Type: GrantFiled: October 14, 1997Date of Patent: September 14, 1999Assignee: The United States of America, as represented by the Secretary of AgricultureInventors: David J. Nisbet, Donald E. Corrier, Larry H. Stanker
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Patent number: 5604127Abstract: A defined probiotic or composition of anaerobic bacteria effective for controlling or inhibiting Salmonella colonization of fowl. The probiotic includes populations or cultures of substantially biologically pure bacteria, which bacteria include:(a) at least one Lactobacillus species;(b) one or both of:Lactococcus lactis, andCitrobacter freundii; and(c) at least one of:one or more Enterococcus species,one or more Bifidobacterium species,one or more Propionibacterium species, andone or more Escherichia species.In use, the probiotic is administered to the subject fowl in an amount effective for inhibiting Salmonella colonization thereof. The invention also relates to a novel method for isolating probiotics which are effective for controlling or inhibiting Salmonella colonization of fowl, from fecal droppings or cecal contents of adult fowl. The droppings or cecal contents are combined with a culture medium and incubated without dilution (i.e. batch culture) under anaerobic conditions.Type: GrantFiled: November 23, 1994Date of Patent: February 18, 1997Assignee: The United States of America as represented by the Secretary of AgricultureInventors: David J. Nisbet, Donald E. Corrier, John R. DeLoach
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Patent number: 5478557Abstract: A defined probiotic or composition of anaerobic bacteria effective for controlling or inhibiting Salmonella colonization of fowl. The probiotic includes populations or cultures of 29 substantially biologically pure bacteria. In use, the probiotic is administered to the subject fowl in an amount effective for increasing resistance to Salmonella colonization thereof.The invention also relates to a novel method for isolating probiotics which are effective for controlling or inhibiting Salmonella colonization of domestic animals, from fecal droppings, cecal contents or large intestines of the adult animals. The droppings, cecal contents or large intestine are combined with a culture medium and incubated without dilution (i.e. batch culture) under anaerobic conditions. Following this preliminary incubation, the resultant culture is subjected to continuous flow conditions until a steady state is achieved, after which time the steady state culture may be recovered for use as a probiotic.Type: GrantFiled: December 13, 1993Date of Patent: December 26, 1995Assignee: The United States of America, as represented by the Secretary of AgricultureInventors: David J. Nisbet, Donald E. Corrier, John R. DeLoach
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Patent number: 5340577Abstract: A defined probiotic or composition of anaerobic bacteria effective for controlling or inhibiting Salmonella colonization of fowl. The probiotic includes populations or cultures of substantially biologically pure bacteria, which bacteria include:(a) at least one Lactobacillus species;(b) one or both of:Lactococcus lactis, andCitrobacter freundii; and(c) at least one of:one or more Enterococcus species,one or more Bifidobacterium species,one or more Propionibacterium species, andone or more Escherichia species.In use, the probiotic is administered to the subject fowl in an amount effective for inhibiting Salmonella colonization thereof.The invention also relates to a novel method for isolating probiotics which are effective for controlling or inhibiting Salmonella colonization of fowl, from fecal droppings or cecal contents of adult fowl. The droppings or cecal contents are combined with a culture medium and incubated without dilution (i.e. batch culture) under anaerobic conditions.Type: GrantFiled: July 29, 1992Date of Patent: August 23, 1994Assignee: The United States of America, as represented by the Secretary of AgricultureInventors: David J. Nisbet, Donald E. Corrier, John R. DeLoach