Patents by Inventor David J. Pickup

David J. Pickup has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified vaccinia ankara virus vaccine
    Patent number: 7972605
    Abstract: The present invention relates, in general, to vaccines and, in particular, to a modified vaccinia Ankara (MVA) virus, to a composition comprising such a virus and to methods of using same to induce an immune response.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: July 5, 2011
    Assignee: Duke University
    Inventors: Dhavalkumar D. Patel, David J. Pickup
  • Modified vaccinia ankara virus vaccine
    Publication number: 20090274723
    Abstract: The present invention relates, in general, to vaccines and, in particular, to a modified vaccinia Ankara (MVA) virus, to a composition comprising such a virus and to methods of using same to induce an immune response.
    Type: Application
    Filed: September 10, 2007
    Publication date: November 5, 2009
    Inventors: David J. Pickup, Dhavalkumar D. Patel
  • Site-specific RNA cleavage
    Patent number: 5578468
    Abstract: The present invention relates to a method of effecting site-specific cleavage of RNA and to an element and a factor responsible for such cleavage.
    Type: Grant
    Filed: August 31, 1993
    Date of Patent: November 26, 1996
    Assignee: Duke University
    Inventors: David J. Pickup, Dhavalkumar Patel, James B. Antczak
  • Poxvirus insertion/expression vector
    Patent number: 5443964
    Abstract: The invention comprises a plasmid vector, utilizing genetic material that causes high levels of expression of poxvirus genes, and the method of using this genetic material. One preferred embodiment comprises an upstream cis-acting element of a poxvirus gene encoding the major protein component of the poxvirus A-type inclusion. A second preferred embodiment of the invention comprises a downstream cis-acting element of a poxvirus gene encoding the major protein component of the poxvirus A-type inclusion. These elements are inserted upstream and downstream respectively, of selected cloned genes in the plasmid vector to obtain very high levels of expression of the cloned gene.
    Type: Grant
    Filed: August 10, 1987
    Date of Patent: August 22, 1995
    Assignee: Duke University
    Inventors: David J. Pickup, Dhavalkumar D. Patel