Abstract: An expandable clot mobilizer device for extraction of an occlusion from a blood vessel is provided, which comprises a working portion including a plurality of crowns of cells. Each cell comprises an open area bordered by two proximal cell struts, two distal cell struts, and two middle cell struts. The proximal cell struts each extending distally from a common proximal end to a proximal end of a respective one of the two middle cell struts, the distal cell struts each extending proximally from a common distal end to a distal end of a respective one of the two middle cell struts, each middle cell strut in each crown bordering two adjacent cells in that crown and each middle cell strut being adapted and configured to be more flexible than the distal cell strut and the proximal cell strut to which it extends. The clot mobilizer also comprises a tapered portion.

Abstract: A self-expandable medical device for advancement through vasculature to an expansion site in a blood vessel is disclosed. The device comprises a working portion and a connection portion that can be connected to a pusher. The working portion provides an outward radial force at every diameter between and including the diameter of a compressed and an expanded configurations, and comprises a plurality of crowns of cells comprising an open area bordered by two proximal cell struts, two distal cell struts, and two middle cell struts. The proximal cell struts each extend distally from a common proximal end to a proximal end of a respective one of the two middle cell struts. The distal cell struts each extend proximally from a common distal end to a distal end of a respective one of the two middle cell struts. Each middle cell strut is more flexible than the distal cell strut and proximal cell strut to which it extends.

Abstract: A method of combinatorial optimization includes: (1) defining an objective function to optimize a combination of N input parameters of a complex system, wherein the objective function includes a weighted sum of n different optimization criteria, N?2, and n?2; (2) applying an initial combination of the N input parameters to the complex system to yield an initial output response; (3) executing an optimization procedure to generate an updated combination of the N input parameters, wherein executing the optimization procedure includes calculating an initial value of the objective function based on at least one of (a) the initial combination of the N input parameters and (b) the initial output response; and (4) applying the updated combination of the N input parameters to the complex system to yield an updated output response.

Abstract: Wearing apparel consisting of a garment which includes a flap with a releasable gripping surface hinged on one of the garment's exposed surface panels and constructed so that the end of the flap which is not hingedly connected can be swung away from the garment's panel to flash or expose a written indicia on the underside of the flap and against the panel so the gripping surface will hold the flap in place on the panel when so positioned.