Patents by Inventor David J. Tester

David J. Tester has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Suppression-Replacement Gene Therapy
    Publication number: 20240093202
    Abstract: Methods and materials for treating a mammal having a congenital disease (e.g., a congenital heart disease such as congenital long QT syndrome) are provided herein. For example, this document provides methods and materials for generating and using nucleic acids to treat a mammal having a congenital disease, where the nucleic acids can suppress expression of mutant disease-related alleles in the mammal while providing a replacement cDNA that does not contain the disease-related mutation(s).
    Type: Application
    Filed: December 30, 2021
    Publication date: March 21, 2024
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Michael J. ACKERMAN, Steven M. DOTZLER, William GENDRON, Sahej BAINS, Changsung John KIM, David J. TESTER
  • RYR2 MUTATIONS
    Publication number: 20080286875
    Abstract: This document provides methods and materials related to assessing a mammal for the presence or absence of a genetic mutation. For example, methods for determining whether or not a mammal contains a genetic mutation in an RyR2 sequence are provided. In addition, isolated nucleic acid molecules containing an RyR2 sequence and encoding a mutation are provided herein.
    Type: Application
    Filed: April 27, 2007
    Publication date: November 20, 2008
    Inventors: Michael J. Ackerman, David J. Tester, Melissa L. Will, Carla M. Haglund