Patents by Inventor David J. von Schack

David J. von Schack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dosage regimen for MAdCAM antagonists
    Patent number: 11884726
    Abstract: The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.
    Type: Grant
    Filed: November 30, 2020
    Date of Patent: January 30, 2024
    Assignee: Pfizer Inc.
    Inventors: Fabio Cataldi, Robert A. Clare, Gail M. Comer, Vivekananda Pradhan, Alaa Ahmad, Mina Hassan-Zahraee, Mera Krishnan Tilley, Weidong Zhang, Anindita Banerjee, Karen Michelle Page, Michael Steven Vincent, David J. Von Schack
  • Dosage Regimen For MAdCAM Antagonists
    Publication number: 20210324070
    Abstract: The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.
    Type: Application
    Filed: November 30, 2020
    Publication date: October 21, 2021
    Inventors: Fabio CATALDI, Robert A. CLARE, Gail M. COMER, Vivekananda PRADHAN, Alaa AHMAD, Mina HASSAN-ZAHRAEE, Mera Krishnan TILLEY, Weidong ZHANG, Anindita BANERJEE, Karen Michelle PAGE, Michael Steven VINCENT, David J. VON SCHACK
  • Dosage regimen for MAdCAM antagonists
    Patent number: 10851163
    Abstract: The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: December 1, 2020
    Assignee: PFIZER INC.
    Inventors: Fabio Cataldi, Robert A. Clare, Gail M. Comer, Vivekananda Pradhan, Alaa Ahmad, Mina Hassan-Zahraee, Mera Krishnan Tilley, Weidong Zhang, Anindita Banerjee, Karen Michelle Page, Michael Steven Vincent, David J. Von Schack
  • DOSAGE REGIMEN FOR MADCAM ANTAGONISTS
    Publication number: 20180273619
    Abstract: The present invention provides a method for the treatment of a patient comprising administering to the patient an initial dose of between about 1 mg and about 150 mg of a MAdCAM antagonist antibody. Biomarkers for assessing a patient's response to anti-MAdCAM treatment are also provided.
    Type: Application
    Filed: January 6, 2016
    Publication date: September 27, 2018
    Inventors: Fabio CATALDI, Robert A. CLARE, Gail M. COMER, Vivekananda PRADHAN, Alaa AHMAD, Mina HASSAN-ZAHRAEE, Mera Krishnan TILLEY, Weidong ZHANG, Anindita BANERJEE, Karen Michelle PAGE, Michael Steven VINCENT, David J. VON SCHACK
  • Methods of Treating Inflammatory Disorders Using Anti-M-CSF Antibodies
    Publication number: 20140286959
    Abstract: The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to a M-CSF, preferably human M-CSF, and that function to inhibit a M-CSF. The invention also relates to human anti-M-CSF antibodies and antigen-binding portions thereof. The invention also relates to antibodies that are chimeric, bispecific, derivatized, single chain antibodies or portions of fusion proteins. The invention also relates to isolated heavy and light chain immunoglobulins derived from human anti-M-CSF antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human anti-M-CSF antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions for diagnosis and treatment. The invention also provides gene therapy methods using nucleic acid molecules encoding the heavy and/or light immunoglobulin molecules that comprise the human anti-M-CSF antibodies.
    Type: Application
    Filed: November 2, 2012
    Publication date: September 25, 2014
    Applicant: PFIZER Inc.
    Inventors: Martin Hegen, Deborah Young, Heath Guay, Kyriaki Dunussi-Joannopoulos, Sudhakar Sridharan, Annette Diehl, Gail Comer, Margot O'Toole, Jean Beebe, Robert Fogel, Marek Honczarenko, David Beidler, Padmalatha S. Reddy, David J. von Schack