Abstract: Techniques and apparatuses are described that implement electromagnetic vector sensors (EMVS) for a smart-device-based radar system. Instead of including an antenna array of similar antenna elements, the radar system includes two or more electromagnetic vector sensors. At least one of the electromagnetic vector sensors is used for transmission and at least another of the electromagnetic vector sensors is used for reception. Each electromagnetic vector sensor includes a group of antennas with different antenna patterns, orientations, and/or polarizations. An overall footprint of the two electromagnetic vector sensors (e.g., one for transmission and one for reception) can be smaller than antenna arrays used by other radar systems, thereby enabling the radar system to be implemented within space-constrained devices.

Abstract: Techniques and apparatuses are described that implement a smart device with an integrated radar system. The radar integrated circuit is positioned towards an upper-middle portion of a smart device to facilitate gesture recognition and reduce a false-alarm rate associated with other non-gesture related motions of a user. The radar integrated circuit is also positioned away from Global Navigation Satellite System (GNSS) antennas and a wireless charging receiver coil to reduce interference. The radar system operates in a low-power mode to reduce power consumption and facilitate mobile operation of the smart device. By limiting a footprint and power consumption of the radar system, the smart device can include other desirable features in a space-limited package (e.g., a camera, a fingerprint sensor, a display, and so forth).

Abstract: Provided herein are protein translation inhibitors and pharmaceutical compositions thereof that bind to an RNA Recognition motif in heterogeneous ribonucleoprotein A18 to inhibit binding to mRNA transcripts thereby inhibiting protein synthesis. Also provided is a method for treating a cancer by administering a pharmaceutically acceptable amounts of at least one of the protein translation inhibitors.

Abstract: Devices are provided that include radar circuits arranged to send and receive radar signals that can be used to, for example, detect gestures performed in the vicinity of the device. Arrangements of the circuits and associated antennas allow for the device to have no bezel or a minimal bezel.

Abstract: Techniques and apparatuses are described that implement electromagnetic vector sensors (EMVS) for a smart-device-based radar system. Instead of including an antenna array of similar antenna elements, the radar system includes two or more electromagnetic vector sensors. At least one of the electromagnetic vector sensors is used for transmission and at least another of the electromagnetic vector sensors is used for reception. Each electromagnetic vector sensor includes a group of antennas with different antenna patterns, orientations, and/or polarizations. An overall footprint of the two electromagnetic vector sensors (e.g., one for transmission and one for reception) can be smaller than antenna arrays used by other radar systems, thereby enabling the radar system to be implemented within space-constrained devices.

Abstract: Techniques and apparatuses are described that implement a smart device with an integrated radar system. The radar integrated circuit is positioned towards an upper-middle portion of a smart device to facilitate gesture recognition and reduce a false-alarm rate associated with other non-gesture related motions of a user. The radar integrated circuit is also positioned away from Global Navigation Satellite System (GNSS) antennas and a wireless charging receiver coil to reduce interference. The radar system operates in a low-power mode to reduce power consumption and facilitate mobile operation of the smart device. By limiting a footprint and power consumption of the radar system, the smart device can include other desirable features in a space-limited package (e.g., a camera, a fingerprint sensor, a display, and so forth).

Abstract: Provided herein are protein translation inhibitors and pharmaceutical compositions thereof that bind to an RNA Recognition motif in heterogeneous ribonucleoprotein A18 to inhibit binding to mRNA transcripts thereby inhibiting protein synthesis. Also provided is a method for treating a cancer by administering a pharmaceutically acceptable amounts of at least one of the protein translation inhibitors.

Abstract: Redundancies of power amplifiers (PAs) or low noise amplifiers (LNAs) at the front end of an RF device are used to reduce losses that typically occur at a diversity switch. A signal designator can advantageously be used to select designated signals, which are provided to the PAs for transmitting or provided by the LNAs during receiving.

Abstract: A modulation system comprising a signal processing unit and a modulator. The signal processing unit may generate a low frequency modulator signal, a high frequency modulator signal, and a modulator amplitude control signal. The modulator may generate a modulated signal for transmission via a wireless network based, at least in part, on the low frequency modulator signal, the high frequency modulator signal, and the modulator amplitude control signal. The signal processing unit comprises a delay compensation unit for delaying the generation of the high frequency modulator signal and the modulator amplitude control signal based, at least in part, on signal generation and modulation path delays associated with the low frequency modulator signal to substantially align the modulator signals at the output of the modulation system.

Abstract: A dual mode power amplifier can include a linear gain section and a non-linear gain section configured together as a polar amplifier. The dual mode power amplifier may be used to transmit GFSK, 4-DPSK, and 8-DPSK modulated data. In one mode, both non-linear and linear gain sections may be used to transmit 4-DPSK and 8-DPSK modulated data. Alternatively, in another mode, the linear gain section may be bypassed while the non-linear gain section may be used to transmit GFSK modulated data. By selecting the operating mode, the dual mode power amplifier may be advantageously configured to use relatively less power while supporting GFSK, 4-DPSK, and 8-DPSK modulation schemes.

Abstract: Multiple power amplifiers in an RF front end are coupled to multiple antennas without diversity switching between the PAs and antennas. Diversity switches direct signals to broadcast by a selected antenna to a PA coupled to the selected antenna. Multiple LNAs are similarly coupled to the diverse antennas. Having one PA and LNA set for each antenna removes the need for diversity switching between the PA/LNAs and each antenna improving signal reception. In one embodiment, a single external PA performs broadcast functions and plural on-chip LNAs are used for reception. In another embodiment, phase shifters are coupled to each PA and LNA, which provide beam forming capability for broadcasts, and in phase signal combinations for received signals.

Abstract: A polar transmitter includes a phase monitoring unit for monitoring input modulating data. When a phase transition exceeds a phase transition threshold, the phase monitor unit can signal an amplitude negation unit to invert the amplitude data coupled to the polar amplifier. The phase monitoring unit can also add an offset to the phase data that is provided to a frequency synthesizer. In another embodiment, when the phase transition threshold is exceeded, the phase monitoring unit can trigger inverting differential frequency data coupled to the polar amplifier. In one embodiment, the phase offset and the amplitude negation are applied until a second phase transition value exceeding the phase transition threshold is detected. If such an event is detected, then the input amplitude data is no longer inverted and the phase offset value is no longer added to the modulating data.

Abstract: A polar transmitter includes a phase monitoring unit for monitoring input modulating data. When a phase transition exceeds a phase transition threshold, the phase monitor unit can signal an amplitude negation unit to invert the amplitude data coupled to the polar amplifier. The phase monitoring unit can also add an offset to the phase data that is provided to a frequency synthesizer. In another embodiment, when the phase transition threshold is exceeded, the phase monitoring unit can trigger inverting differential frequency data coupled to the polar amplifier. In one embodiment, the phase offset and the amplitude negation are applied until a second phase transition value exceeding the phase transition threshold is detected. If such an event is detected, then the input amplitude data is no longer inverted and the phase offset value is no longer added to the modulating data.

Abstract: A polar transmitter includes a phase monitoring unit for monitoring input modulating data. When a phase transition exceeds a phase transition threshold, the phase monitor unit can signal an amplitude negation unit to invert the amplitude data coupled to the polar amplifier. The phase monitoring unit can also add an offset to the phase data that is provided to a frequency synthesizer. In another embodiment, when the phase transition threshold is exceeded, the phase monitoring unit can trigger inverting differential frequency data coupled to the polar amplifier. In one embodiment, the phase offset and the amplitude negation are applied until a second phase transition value exceeding the phase transition threshold is detected. If such an event is detected, then the input amplitude data is no longer inverted and the phase offset value is no longer added to the modulating data.

Abstract: An apparatus for processing a Bluetooth signal advantageously mixes down a received RF signal to an IF signal wherein one band-edge of the spectrum of the IF signal may be approximately 0 Hz. In one embodiment, the IF signal may be digitized, decimated and filtered before being processed into a baseband signal. The baseband signal may be processed by a cordic (COordinate Rotation DIgital Computer) processor to transform the baseband signal from rectangular to polar coordinates. A phase signal from the cordic processor may be used to determine transmitted Bluetooth data symbols. The apparatus may advantageously use less area than traditional Bluetooth receivers.

Abstract: Compounds that bind S100 and inhibit the S100-p53 protein-protein interaction and activate the tumor suppressor activity of p53, and thus which have an antineoplastic effect are disclosed, as well as methods for identifying these compounds, compositions comprising the same, and methods of using the same to treat cancer.

Abstract: A modulation system comprising a signal processing unit and a modulator. The signal processing unit may generate a low frequency modulator signal, a high frequency modulator signal, and a modulator amplitude control signal. The modulator may generate a modulated signal for transmission via a wireless network based, at least in part, on the low frequency modulator signal, the high frequency modulator signal, and the modulator amplitude control signal. The signal processing unit comprises a delay compensation unit for delaying the generation of the high frequency modulator signal and the modulator amplitude control signal based, at least in part, on signal generation and modulation path delays associated with the low frequency modulator signal to substantially align the modulator signals at the output of the modulation system.

Abstract: Multiple power amplifiers in an RF front end are coupled to multiple antennas without diversity switching between the PAs and antennas. Diversity switches direct signals to broadcast by a selected antenna to a PA coupled to the selected antenna. Multiple LNAs are similarly coupled to the diverse antennas. Having one PA and LNA set for each antenna removes the need for diversity switching between the PA/LNAs and each antenna improving signal reception. In one embodiment, a single external PA performs broadcast functions and plural on-chip LNAs are used for reception. In another embodiment, phase shifters are coupled to each PA and LNA, which provide beam forming capability for broadcasts, and in phase signal combinations for received signals.

Abstract: A dual mode power amplifier can include a linear gain section and a non-linear gain section configured together as a polar amplifier. The dual mode power amplifier may be used to transmit GFSK, 4-DPSK, and 8-DPSK modulated data. In one mode, both non-linear and linear gain sections may be used to transmit 4-DPSK and 8-DPSK modulated data. Alternatively, in another mode, the linear gain section may be bypassed while the non-linear gain section may be used to transmit GFSK modulated data. By selecting the operating mode, the dual mode power amplifier may be advantageously configured to use relatively less power while supporting GFSK, 4-DPSK, and 8-DPSK modulation schemes.

Abstract: An interleaved ADC can advantageously provide synchronous sampling and time-multiplexed output. Differential I and Q input signals can first be stored by charging a plurality of capacitors. These stored differential signals can be buffered in a time-multiplexed sequence. For example, buffering can include transferring voltages stored by a first set of capacitors at a first time and then transferring voltages stored by a second set of capacitors at a second time. Advantageously, this time-multiplexing allow the ADC to be significantly smaller than conventional implementations of two-input ADCs. A folded mixer with gain control is also provided. This mixer can include a first stage having a first set of inductors and a plurality of first type transistors and a second stage having a second set of inductors and a plurality of second type transistors. The plurality of second type transistors in the second stage, which are in a folded configuration, can be driven by the first set of inductors in the first stage.