Patents by Inventor David J. Yang

David J. Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Water soluble paclitaxel derivatives
    Publication number: 20040018960
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: July 14, 2003
    Publication date: January 29, 2004
    Applicant: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel derivatives
    Publication number: 20030176320
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: January 30, 2003
    Publication date: September 18, 2003
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel derivatives
    Publication number: 20030147807
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: December 5, 2002
    Publication date: August 7, 2003
    Applicant: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel derivatives
    Publication number: 20030134793
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or -lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: October 28, 2002
    Publication date: July 17, 2003
    Applicant: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel dervatives
    Publication number: 20030130178
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: November 18, 2002
    Publication date: July 10, 2003
    Applicant: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel derivatives
    Publication number: 20030130170
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: November 18, 2002
    Publication date: July 10, 2003
    Applicant: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel derivatives
    Publication number: 20030130341
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: November 18, 2002
    Publication date: July 10, 2003
    Applicant: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Imaging agents, precursors thereof and methods of manufacture
    Publication number: 20030124059
    Abstract: Compounds of formula (I) and (II): 1
    Type: Application
    Filed: June 4, 2001
    Publication date: July 3, 2003
    Inventors: Akira Tanaka, Tomio Inoue, Katsumi Tomiyoshi, David J. Yang, E. Edmund Kim
  • Water soluble paclitaxel derivatives
    Publication number: 20030124055
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: December 5, 2002
    Publication date: July 3, 2003
    Applicant: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel derivatives
    Publication number: 20030113335
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: September 12, 2002
    Publication date: June 19, 2003
    Applicant: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel derivatives
    Publication number: 20030114397
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: September 12, 2002
    Publication date: June 19, 2003
    Applicant: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel derivatives
    Publication number: 20030114363
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: September 12, 2002
    Publication date: June 19, 2003
    Applicant: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel derivatives
    Publication number: 20030114518
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: September 12, 2002
    Publication date: June 19, 2003
    Applicant: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Anticancer polypeptide-metal complexes and compositions, methods of making, and methods of using same
    Publication number: 20030109432
    Abstract: Novel drug complexes comprising a polypeptide carrier moiety comprising glutamic acid and at least one of the group consisting of aspartic acid, alanine, asparagine, glutamine, glycine, and any combinations thereof, are disclosed. The drug moiety is a therapeutic metal selected from the group consisting of platinum, iron, gadolinium, rhenium, manganese, cobalt, indium, gallium or rhodium. Methods for making said complexes, compositions comprising said complexes, methods for making saiduch compositions, and methods for treating a patient comprising use of said complexes and/or compositions are further disclosed.
    Type: Application
    Filed: December 10, 2001
    Publication date: June 12, 2003
    Inventors: William W. Zuo, Dongfang Yu, David J. Yang, Jing Ya Xu
  • Water soluble paclitaxel derivatives
    Publication number: 20030073617
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: October 28, 2002
    Publication date: April 17, 2003
    Applicant: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel derivatives
    Publication number: 20030073615
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: May 17, 2002
    Publication date: April 17, 2003
    Applicant: Cell Therapeutics, Inc.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel derivatives
    Patent number: 6441025
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Grant
    Filed: March 30, 1998
    Date of Patent: August 27, 2002
    Assignee: PG-TXL Company, L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • WATER SOLUBLE PACLITAXEL DERIVATIVES
    Publication number: 20010034363
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or poly-lysine. Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Application
    Filed: March 30, 1998
    Publication date: October 25, 2001
    Inventors: CHUN LI, SIDNEY WALLACE, DONG-FANG YU, DAVID J. YANG
  • Water soluble paclitaxel prodrugs
    Patent number: 6262107
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble chelator, polyethylene glycol or polymer such as poly (1-glutamic acid) or poly (1-aspartic acid). Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis and for prediction of paclitaxel uptake by tumors and radiolabeled DTPA-paclitaxel tumor imaging. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Grant
    Filed: July 1, 1999
    Date of Patent: July 17, 2001
    Assignee: PG-TXL Company L.P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang
  • Water soluble paclitaxel prodrugs
    Patent number: 5977163
    Abstract: Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble chelator, polyethylene glycol or polymer such as poly (1-glutamic acid) or poly (1-aspartic acid). Also disclosed are methods of using the compositions for treatment of tumors, auto-immune disorders such as rheumatoid arthritis and for prediction of paclitaxel uptake by tumors and radiolabeled DTPA-paclitaxel tumor imaging. Other embodiments include the coating of implantable stents for prevention of restenosis.
    Type: Grant
    Filed: March 11, 1997
    Date of Patent: November 2, 1999
    Assignee: PG-TXL Company, L. P.
    Inventors: Chun Li, Sidney Wallace, Dong-Fang Yu, David J. Yang