Abstract: There is disclosed a nanopore support structure comprising a wall layer comprising walls defining a plurality of wells, and overhangs extending from the walls across each of the wells, the overhang defining an aperture configured to support a membrane suitable for insertion of a nanopore. There is further disclosed a nanopore sensing device comprising a nanopore support structure, and methods of manufacturing the nanopore support structure and the nanopore sensing device.

Abstract: Vehicle alignment systems and methods are disclosed which operate based on a calculation of “drive direction,” or the direction in which a vehicle is moving. Since a vehicle can be assumed to be a rigid body, each wheel has the same drive direction. Consequently, an alignment parameter of one wheel can be compared to the same parameter of another wheel by equating their drive direction, eliminating the need for the aligner to “see” both sides of the vehicle at the same time. Embodiments include a system having one or more cameras on a fixture carrying a calibration element for an ADAS system, and one or more targets placed on the vehicle to measure the drive direction of the vehicle. The drive direction is assumed to be parallel to the vehicle thrust line and can be used as the line for orientation of the fixture to the vehicle.

Abstract: Vehicle alignment systems and methods are disclosed which operate based on a calculation of “drive direction,” or the direction in which a vehicle is moving. Since a vehicle can be assumed to be a rigid body, each wheel has the same drive direction. Consequently, an alignment parameter of one wheel can be compared to the same parameter of another wheel by equating their drive direction, eliminating the need for the aligner to “see” both sides of the vehicle at the same time. Embodiments include a system having one or more cameras on a fixture carrying a calibration element for an ADAS system, and one or more targets placed on the vehicle to measure the drive direction of the vehicle. The drive direction is assumed to be parallel to the vehicle thrust line and can be used as the line for orientation of the fixture to the vehicle.

Abstract: A system, method and apparatus for verified mailing documents and process preparation are disclosed. The disclosed comprise of a trusted agent, being a device adapted for secure verification of a person or entity that transmits a certified mailed document, a data source or engine from whose data a verified document may be generated, a mailing request recipient means adapted to receive requests to mail and/or transmit a certified document to an address of service, and a verification means to verify the authenticity of a requesting person or entity, preferably using biometric authentication means.

Abstract: Disclosed is an improved string saddle or yoke that can have a string bent thereover without causing a separation of the string's windings.

Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

Abstract: A projection system and calibration method therefor relate to a light source configured to emit a light in response to an image data, an illumination optical system configured to steer the light, the illumination optical system including a first minor and a second minor, a digital micromirror device (DMD) including a plurality of micromirrors respectively configured to reflect the steered light to a filter as on-state light or to reflect the steered light as off-state light to a light dump; determining a deviation between an actual angle of orientation and an expected angle of orientation of the DMD; calculating a first amount of angle adjustment corresponding to the first minor and a second amount of angle adjustment corresponding to the second mirror; and actuating the first mirror according to the first amount and the second mirror according to the second amount.

Abstract: The invention relates to a method for modifying a template double stranded polynucleotide, especially for characterisation using nanopore sequencing. The method produces from the template a plurality of modified double stranded polynucleotides. These modified polynucleotides can then be characterised.

Abstract: Methods and systems measure a vehicle body parameter; e.g., a wheel alignment parameter such as ride height. Embodiments include a system having a target attachable to a vehicle body, and an image sensor for viewing the target and capturing image data thereof. A processor processes the image data, determines an initial spatial position of the target based on the processed image data, compares the initial spatial position of the target with a reference position, and prompts a user to align the target to an adjusted spatial position when the initial spatial position differs from the reference position more than a threshold amount. The vehicle body parameter value is determined based on the target's adjusted spatial position. In certain embodiments, the adjusted spatial position differs from the reference position by a position error value, and the processor mathematically corrects the vehicle body parameter value based on the position error value.

Abstract: Disclosed is an improved string saddle or yoke that can have a string bent thereover without causing a separation of the string's windings.

Abstract: A projection display system comprises a light source configured to emit a light in response to a content data; an optical modulator configured to modulate the light; and a controller configured to adjust a light level of the projection display system based on the content data and a metadata relating to a future frame, thereby to reduce a perceptibility of a visual artifact.

Abstract: A novel projection system includes a base signal source, a highlight signal source, a base/highlight destination, and a shared optical element. A base signal provided by the base source and a highlight signal provided by the highlight source are combined by the shared optical element. In a particular embodiment, the base signal source and the highlight signal source each include a light source, a spatial light modulator, and optics, and the base/highlight destination includes optics and a spatial light modulator. In a more particular embodiment, the base signal source and the highlight source provide spatially modulated lightfields to the shared optical element. In another particular embodiment, the base signal and the highlight signal are modulated by the spatial light modulator of the base/highlight destination after being combined.

Abstract: Methods of characterizing an analyte using a nanopore. One aspect features methods for characterizing a double-stranded polynucleotide using a nanopore, e.g., without using a hairpin connecting a template and a complement of the double-stranded polynucleotide. Another aspect features methods for characterizing an analyte using a tag-modified nanopore with increased sensitivity and/or higher throughput. Compositions and systems including, e.g., adaptors for attachment to double-stranded polynucleotides and tag-modified nanopores, which can be used in the methods are also provided.

Abstract: A method including: detecting a request for a first part of a video; detecting a request for a second part of the video, wherein the video has a video timeline and the second part of the video immediately follows the first part of the video in the video timeline; after detecting the request for the first part of the video and prior to detecting the request for the second part of the video, transmitting a request for a third part of the video, wherein the third part of the video follows the second part of the video in the video timeline; receiving the requested third part of the video; and storing the received third part of the video.

Abstract: An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

Abstract: A projection lens system and method therefor relate to a Fourier lens assembly including a first attachment section, the Fourier lens assembly configured to form a Fourier transform of an object at an exit pupil of the Fourier lens assembly; an aperture configured to block a portion of 5 incident light, the aperture located approximately at a plane of the Fourier transform; and a zoom lens assembly including a second attachment section configured to be removably attached to the first attachment section.

Abstract: A process is presented to treat a process gas stream containing hydrogen sulfide using a reverse jet absorber with a liquid treatment solution containing a chelated metal catalyst. A treat gas substantially free of the hydrogen sulfide is separated from a spent liquid treatment solution containing elemental sulfur which can then be regenerated in an oxidation vessel where it is contacted with an oxygen containing gas to convert the spent liquid treatment solution to a regenerated liquid treatment solution that can be recycled for introduction into the reverse jet absorber.

Abstract: A process is presented to treat a process gas stream containing hydrogen sulfide using a reverse jet absorber with a liquid treatment solution containing a chelated metal catalyst. A treat gas substantially free of the hydrogen sulfide is separated from a spent liquid treatment solution containing elemental sulfur which can then be regenerated in an oxidation vessel where it is contacted with an oxygen containing gas to convert the spent liquid treatment solution to a regenerated liquid treatment solution that can be recycled for introduction into the reverse jet absorber.

Abstract: The present disclosure relates to aerosol delivery devices. The aerosol delivery devices include mechanisms configured to deliver an aerosol precursor composition from a reservoir to an atomizer including a vaporization heating element to produce a vapor. For example, a bubble jet head may be configured to dispense the aerosol precursor composition to the atomizer. The bubble jet head may be fixedly coupled to the atomizer. The bubble jet head may include a precursor inlet, an ejection heating element, and a precursor nozzle. The atomizer may include a vaporization heating element.

Abstract: The invention relates to a method of forming a sensing device for supporting a plurality of nanopores upon an array of wells. The method involves providing a substrate, said substrate having a surface having an array of electrodes located thereon for connecting to or for configuring upon an electronic circuit. Separately, a well array structure is provided, which has an array of walls defining through-holes for defining wells. The substrate and well array structures are aligning said array of electrodes define, at least in part, a portion of the bases of respective wells at the bottom of the through holes. The resulting sensing device overcomes problems with known sensing devices by employing a substrate and/or well array structure, or hybrid thereof, that employs alternative materials or manufacturing processes.