Patents by Inventor David James Hakes

David James Hakes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FACTOR VIII: REMODELING AND GLYCOCONJUGATION OF FACTOR VIII
    Publication number: 20160200795
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: December 18, 2015
    Publication date: July 14, 2016
    Applicant: Novo Nordisk A/S
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, Caryn Bowe, David James Hakes, Xi Chen
  • FACTOR VIII: REMODELING AND GLYCOCONJUGATION OF FACTOR VIII
    Publication number: 20160193353
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: March 16, 2016
    Publication date: July 7, 2016
    Applicant: Novo Nordisk A/S
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, Caryn Bowe, David James Hakes, Xi Chen
  • GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS
    Publication number: 20150343080
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: May 26, 2015
    Publication date: December 3, 2015
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, David James Hakes, Caryn L. Bowe, Xi Chen
  • Glycopegylation methods and proteins/peptides produced by the methods
    Patent number: 8853161
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: October 7, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, David James Hakes, Caryn Bowe, Xi Chen
  • GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS
    Publication number: 20140294762
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: April 7, 2014
    Publication date: October 2, 2014
    Applicant: Novo Nordisk A/S
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, David James Hakes, Caryn L. Bowe, Xi Chen
  • Factor IX: Remodeling and Glycoconjugation of Factor IX
    Publication number: 20140170728
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: December 6, 2013
    Publication date: June 19, 2014
    Applicant: Novo Nordisk A/S
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, Caryn Bowe, David James Hakes, Xi Chen
  • Erythropoietin: remodeling and glycoconjugation of erythropoietin
    Patent number: 8716240
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Grant
    Filed: February 2, 2007
    Date of Patent: May 6, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, Caryn Bowe, David James Hakes, Xi Chen
  • Granulocyte colony stimulating factor: remodeling and glycoconjugation G-CSF
    Patent number: 8716239
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: May 6, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, Caryn Bowe, David James Hakes, Xi Chen
  • Glycopegylation Methods and Proteins/Peptides Produced by the Methods
    Publication number: 20120220517
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: September 27, 2011
    Publication date: August 30, 2012
    Applicant: NOVO NORDISK A/S
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, David James Hakes, Caryn Bowe, Xi Chen
  • Factor VIII: remodeling and glycoconjugation of factor VIII
    Patent number: 8076292
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: December 13, 2011
    Assignee: Novo Nordisk A/S
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, Caryn Bowe, David James Hakes, Xi Chen
  • Glycopegylation methods and proteins/peptides produced by the methods
    Patent number: 8063015
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: November 22, 2011
    Assignee: Novo Nordisk A/S
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, David James Hakes, Caryn L. Bowe, Xi Chen
  • Factor VIII: remodeling and glycoconjugation of factor VIII
    Publication number: 20100261872
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: December 21, 2006
    Publication date: October 14, 2010
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, Caryn Bowe, David James Hakes, Xi Chen
  • Erythropoietin: remodeling and glycoconjugation of erythropoietin
    Patent number: 7696163
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Grant
    Filed: October 8, 2003
    Date of Patent: April 13, 2010
    Assignee: Novo Nordisk A/S
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, David James Hakes, Caryn Bowe, Xi Chen
  • GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS
    Publication number: 20100048456
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: July 1, 2009
    Publication date: February 25, 2010
    Applicant: Novo Nordisk A/S
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, David James Hakes, Caryn Bowe, Xi Chen
  • Glycopegylation methods and proteins/peptides produced by the methods
    Publication number: 20090093399
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: January 24, 2007
    Publication date: April 9, 2009
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, Caryn Bowe, David James Hakes, Xi Chen
  • Remodeling and glycoconjugation of peptides
    Patent number: 7473680
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group a peptide.
    Type: Grant
    Filed: July 15, 2005
    Date of Patent: January 6, 2009
    Assignee: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, David James Hakes, Caryn Bowe, Xi Chen
  • Truncated St6galnaci Polypeptides and Nucleic Acids
    Publication number: 20080206810
    Abstract: The present invention features compositions and methods related to truncated mutants of ST6GalNAcI. In particular, the invention features truncated human, mouse, and chicken ST6GalNAcI polypeptides. The invention also features nucleic acids encoding such truncated polypeptides, as well as vectors, host cells, expression systems, and methods of expressing and using such polypeptides.
    Type: Application
    Filed: June 3, 2005
    Publication date: August 28, 2008
    Applicant: Neose Technologies, Inc.
    Inventors: Karl F. Johnson, David James Hakes, Ge Wei, Li Liu, Sami Saribas, Eric R. Sjoberg, Henrik Clausen, Eric Paul Bennett, Aliakbar Mobasseri
  • Pharmaceutical compositions of glycoconjugates
    Patent number: 7416858
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group of peptide.
    Type: Grant
    Filed: October 9, 2002
    Date of Patent: August 26, 2008
    Assignee: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, Caryn Bowe, David James Hakes, Xi Chen
  • Erythropoietin: remodeling and glycoconjugation of erythropoietin
    Publication number: 20080187955
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: February 2, 2007
    Publication date: August 7, 2008
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, Caryn Bowe, David James Hakes, Xi Chen
  • Glycoconjugation methods and proteins/peptides produced by the methods
    Publication number: 20080146494
    Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.
    Type: Application
    Filed: March 5, 2007
    Publication date: June 19, 2008
    Applicant: Neose Technologies, Inc.
    Inventors: Shawn DeFrees, David A. Zopf, Robert J. Bayer, Caryn Bowe, David James Hakes, Xi Chen