Abstract: A pretreating device, and method, that is intuitive for the customer, ensures good penetration of the liquid laundry detergent composition into a stain, particularly greasy stains, and is suitable for washing delicate fabrics, particularly at low temperatures.

Abstract: The present invention relates to sulfonamide derivatives, of formula (I): or a pharmaceutically acceptable salts thereof, wherein X, Z, R1a, R1b, R2, R3, R4 and R5 are as defined in the description, and to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. The compounds of formula (I) are Nav1.7 inhibitors useful in the treatment of a wide range of disorders, particularly pain.

Abstract: A data processing system with data transmit capability comprising an operating system for supporting processes, such that the process are associated with one or more resources and the operating system being arranged to police the accessing by processes of resources so as to inhibit a process from accessing resources with which it is not associated. Part of this system is an interface for interfacing between each process and the operating system and a memory for storing state information for at least one process. The interface may be arranged to analyze instructions from the processes to the operating system, and upon detecting an instruction to re-initialize a process cause state information corresponding to that pre-existing state information to be stored in the memory as state information for the re-initialized process and to be associated with the resource.

Abstract: Embodiments of apparatuses and methods for separating a paraffin isomerization-zone effluent are provided. In one example, an apparatus comprises a DIB column configured for fractionating the paraffin isomerization-zone effluent to form a branched C4 hydrocarbon-rich stream. The DIB column comprises a vessel. The vessel comprises a cylindrical wall that extends vertically and that encloses an internal cylindrical volume having a lower portion extending to an upper portion. An internal swage is disposed in the lower portion of the internal cylindrical volume. A plurality of fractionation trays includes an upper fractionation tray that is disposed in the internal cylindrical volume above the internal swage and a lower fractionation tray that is disposed in the internal swage. The lower fractionation tray has a smaller diameter than the upper fractionation tray.

Abstract: A data processing system with routing tables comprising an operating system for supporting processes, such that the process are associated with one or more resources and the operating system being arranged to police the accessing by processes of resources so as to inhibit a process from accessing resources with which it is not associated. Part of this system is an interface for interfacing between each process and the operating system and a memory for storing state information for at least one process. The interface may be arranged to analyze instructions from the processes to the operating system, and upon detecting an instruction to re-initialize a process cause state information corresponding to that pre-existing state information to be stored in the memory as state information for the re-initialized process and to be associated with the resource.

Abstract: A system, server, and method are provided for delivering at least one web feed to at least one wireless device. The server subscribes to the at least one web feed. The server has a processor connected to a memory with at least one module stored in the memory for execution by the processor. The server is configured to: monitor the web feed status for an expiration of a refresh time; retrieve new content from the web feed upon expiry of the refresh time; process the new content and package the processed new content as a content package for delivery to the wireless device; and send the content package to the wireless device as a push delivery.

Abstract: Compounds of formula I wherein: R1 is and R2, R4, and R6-9 are defined herein, and pharmaceutically acceptable salts and esters thereof. These compounds inhibit PI3 kinase and mTOR, and may be used to treat diseases mediated by PI3 kinase and mTOR, such as a variety of cancers. Methods for making and using the compounds of this invention are disclosed. Various compositions containing the compounds of this invention are also disclosed.

Abstract: An exemplary radar mounting device for attaching a component to a vehicle body may include a resilient grommet secured within an opening formed in the component. The device may also have a stud for attachment to the vehicle body. The stud may have a ball portion received within the resilient grommet for attaching the component to the stud. In addition, the device may have a nut fastened to the stud to secure the component to the stud.

Abstract: A floor cleaning machine has a housing and a movable hood that covers over vacuum and liquid hoses of the machine that are visible in prior art floor cleaning machines. The vacuum and liquid hoses are each pivotally connected to a wall of the machine housing and are also pivotally connected to a transparent dome provided on the hood. These connections reduce stresses on the hoses when the hood is moved and allow the dome to pivot relative to the hood. The floor cleaning machine also has a pair of slit orifices that eject fan spray patterns of cleaning liquid that are non-coplanar and do not intersect each other. Furthermore, the floor cleaning machine has an oscillating brush assembly that includes a brush that is replaceable without using tools. The brush height can be adjusted via an adjustment member provided on the oscillating portion of the assembly.

Abstract: An adjustable tower stud assembly is disclosed for securing an object, such as a roof rack, to an external panel such as the roof of a vehicle. The object requires more support than can be provided by the external panel and it is also connected to a sub-surface support. Upper and lower collared studs are connected by a threaded connection that allows the length of the tower stud assembly to be adjusted. Stops on a lower collar ground the tower stud assembly to the sub-surface support after the tower stud assembly is adjusted to the proper length.

Abstract: The invention relates to modified polymerase enzymes which exhibit improved incorporation of nucleotide analogs bearing substituents at the 3? position of the sugar moiety that are larger in size than the naturally occurring 3? hydroxyl group. Also described are methods of using the polymerases to incorporate nucleotides into polynucleotides, particularly in the context of DNA sequencing.

Abstract: Improved recyclability of phosphors in fluorescent lamps is provided. A fluorescent lamp is constructed with phosphor particles having a specific surface area less than a certain predetermined value. During recycling, these phosphor particles are more readily separated from the basing cement used in such fluorescent lamp. A method is also provided by which such phosphors are more readily separated from the basing cement.

Abstract: A network interface device capable of communication with a data processing system supporting an operating system and at least one application, the network interface device supporting communication with the operating system by means of: two or more data channels, each data channel being individually addressable by the network interface device and being capable of carrying application-level data between the network interface device and the data processing device; and a control channel individually addressable by the network interface device and capable of carrying control data between the network interface device, the control data defining commands and the network interface being responsive to at least one command sent over the control channel to establish at least one additional data channel.

Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.

Abstract: A system and method for electrically shielding a physiological pathway from electrical noise is disclosed. The method includes the operation of implanting at least one signal microelectrode into a patient such that the signal microelectrode is proximate to the physiological pathway. An additional operation includes substantially enclosing the microelectrode and a section of the physiological pathway with an electrical shielding wrap. The electrical shielding wrap includes a plurality of holes that enable fluid communication of physiological fluids between an inside and outside of the wrap.

Abstract: A method for running a Self Organizing Network (SON) module in a communication network provides an open Application Programming Interface (API) for a SON framework and executes the SON module. The SON module accesses the functionality of the SON framework using the API. The SON module may be built by a developer other than a SON system provider and may be loaded into the SON framework by an operator other than a SON system provider. The SON module may be implemented as a state machine.

Abstract: A floor cleaning machine has a housing and a movable hood that covers over vacuum and liquid hoses of the machine that are visible in prior art floor cleaning machines. The vacuum and liquid hoses are each pivotally connected to a wall of the machine housing and are also pivotally connected to a transparent dome provided on the hood. These connections reduce stresses on the hoses when the hood is moved and allow the dome to pivot relative to the hood. The floor cleaning machine also has a pair of slit orifices that eject fan spray patterns of cleaning liquid that are non-coplanar and do not intersect each other. Furthermore, the floor cleaning machine has an oscillating brush assembly that includes a brush that is replaceable without using tools. The brush height can be adjusted via an adjustment member provided on the oscillating portion of the assembly.

Abstract: The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide.

Abstract: An automated testing system includes systems and methods to facilitate inline production testing of samples at a micro (multiple microns) or less scale with a mechanical testing instrument. In an example, the system includes a probe changing assembly for coupling and decoupling a probe of the instrument. The probe changing assembly includes a probe change unit configured to grasp one of a plurality of probes in a probe magazine and couple one of the probes with an instrument probe receptacle. An actuator is coupled with the probe change unit, and the actuator is configured to move and align the probe change unit with the probe magazine and the instrument probe receptacle. In another example, the automated testing system includes a multiple degree of freedom stage for aligning a sample testing location with the instrument. The stage includes a sample stage and a stage actuator assembly including translational and rotational actuators.