Abstract: Tire present invention relates to protopoiphyrinogen oxidase inhibitors of the general formula (I) where the variables are defined herein. The invention features processes and intermediates for preparing the compounds of formula (I), compositions comprising them, and their use as herbicides i.e. for controlling undesired vegetation. The invention also features methods for controlling unwanted vegetation comprising allowing an herbicidal effective amount of at least one benzoxazinone of formula (I) to act on plants, their seed, and/or their environment.

Abstract: Disclosed herein are engineered AAV VP capsid polypeptides with the ability to assemble into virus particles and having improved tissue tropism to eye tissues, for example, retinal tissues, retinal pigment epithelial cells, or photoreceptor cells. The capsids are engineered using the high throughput discovery system described herein. In certain embodiments, provided herein are recombinant adeno-associated virus (AAV) VP capsid polypeptides having at least one mutation in a 581 to 589 region of the VP capsid polypeptide, corresponding to residues 581 to residue 589 of a VP1 polypeptide of SEQ ID NO: 1.

Abstract: A scientific instrument support apparatus includes memory hardware configured to store instructions and processing hardware configured to execute the instructions.

Abstract: A method of immunizing a human female subject to decrease the risk of Group B Streptococcus (GBS) disease in an infant born to the subject, by providing a priming dose of a GBS vaccine and, more than thirty days after the priming dose, providing a boosting dose of a GBS vaccine.

Abstract: Provided is a system and method for enabling of access to a computer resource by a computer system comprising: providing to a user an interface configured to receive a request for access to a computer resource; determining if the user is permitted to access the computer resource based on a user profile; providing a user verification interface configured to receive user identity verification information; determining if the user identity verification information is valid in response to a reply to the request for user identify verification information; and in response to determining that the user is permitted access to the computer resource and that the user verification information is valid: updating a security policy to reflect that the user is permitted to access the computer resource, and providing access to the computer resource for a limited time duration.

Abstract: Systems and methods are provided for detecting a shortfall condition with respect to a subscription agreement between a publisher and a subscriber, particularly in a network environment. A method, according to one implementation, includes the steps of examining measurable aspects of real-world subscription events between a publisher and a subscriber in a distributed system. The method also includes the step of comparing the measurable aspects with a subscription agreement between the publisher and the subscriber to determine if there is a shortfall with respect to the subscription agreement.

Abstract: A coaxial cable connector assembly comprising a rear body comprising an outer body member and an inner body member, wherein the rear body is positionable in a disengaged position and an engaged position, and a coupler rotatably engaged with and positioned forward of the rear body, wherein the coupler defines an inner channel extending through the coupler between a front portion of the coupler and a rear portion of the coupler positioned opposite the front portion, a thread at the front portion of the coupler, a nominal portion defining a nominal inner span along the inner channel, and an outer conductor engagement portion that tapers inwardly from the nominal portion that extends forwardly along the inner channel to the front portion of the coupler, wherein the outer conductor engagement portion is structurally configured to contact an outer conductor of the coaxial cable.

Abstract: The present invention relates to protoporphyrinogen IX oxidase (PPO) inhibitors of the general formula (I) where the variables are defined herein. The invention features processes and intermediates for preparing the compounds of formula (I), compositions comprising them, and their use as herbicides—e.g., for controlling harmful plants. The invention also features methods for controlling unwanted vegetation comprising allowing an herbicidal effective amount of at least one PPO inhibitor of formula (I) to act on plants, their seed, and/or their habitat.

Abstract: A coaxial cable connector assembly including a rear body, a coupler rotatably engaged with the rear body, where the coupler defines an inner channel extending through the coupler between a front portion of the coupler and a rear portion of the coupler, and a nominal portion defining a nominal inner span along the inner channel, and a retainer engaged with the coupler and the rear body, where the retainer couples the coupler to the rear body, where at least one of the retainer and the coupler defines an engagement passage having a non-uniform span, where at least a portion of the engagement passage extends inwardly from the nominal portion of the coupler and is structurally configured to contact an outer conductor of the coaxial cable forming an electrical pathway between the thread of the coupler and the outer conductor of the coaxial cable.

Abstract: Provided are binding molecules, such as TCRs or antigen binding fragments thereof and antibodies and antigen-binding fragments thereof, such as those that recognize or bind human papilloma virus (HPV) 16, including HPV 16 E6 and HPV 16 E7. Also provided are engineered cells containing such binding molecules, compositions containing the binding molecules or engineered cells, and methods of treatment, such as administration of the binding molecules, engineered cells, or compositions.

Abstract: Systems and methods are provided for detecting a shortfall condition with respect to a subscription agreement between a publisher and a subscriber, particularly in a network environment. A method, according to one implementation, includes the steps of examining measurable aspects of real-world subscription events between a publisher and a subscriber in a distributed system. The method also includes the step of comparing the measurable aspects with a subscription agreement between the publisher and the subscriber to determine if there is a shortfall with respect to the subscription agreement.

Abstract: The present invention relates to protoporphyrinogen IX oxidase (PPO) inhibitors of the general formula (I) where the variables are defined herein. The invention features processes and intermediates for preparing the compounds of formula (I), compositions comprising them, and their use as herbicides—e.g., for controlling harmful plants. The invention also features methods for controlling unwanted vegetation comprising allowing an herbicidal effective amount of at least one PPO inhibitor of formula (I) to act on plants, their seed, and/or their habitat.

Abstract: A method of online event selection system incorporating a user terminal, server where the user is required to make an account distinguishing on the basis of location via location service function enabled and or user input. In the further embodiment of the invention, the system provides an interactive display allowing members to see the most populated social venues, events, and or location; in any given location with multiple novel features including but not limited to point system, allocation of points to users and locking of events for the user.

Abstract: Provided is a system and method for enabling of access to a computer resource by a computer system comprising: providing to a user an interface configured to receive a request for access to a computer resource; determining if the user is permitted to access the computer resource based on a user profile; providing a user verification interface configured to receive user identity verification information; determining if the user identity verification information is valid in response to a reply to the request for user identify verification information; and in response to determining that the user is permitted access to the computer resource and that the user verification information is valid: updating a security policy to reflect that the user is permitted to access the computer resource, and providing access to the computer resource for a limited time duration.

Abstract: The present invention relates to protoporphyrinogen oxidase inhibitors of the general formula (I) where the variables are defined herein. The invention features processes and intermediates for preparing the benzoxazinones of formula (I), compositions comprising them, and their use as herbicides—i.e. for controlling harmful plants. The invention also features methods for controlling unwanted vegetation comprising allowing an herbicidal effective amount of at least one benzoxazinone of formula (I) to act on plants, their seed, and/or their habitat.

Abstract: The present invention relates to protoporphyrinogen oxidase inhibitors of the general formula (I) where the variables are defined herein. The invention features processes and intermediates for preparing the benzoxazinones of formula (I), compositions comprising them, and their use as herbicides—i.e. for controlling harmful plants. The invention also features methods for controlling unwanted vegetation comprising allowing an herbicidal effective amount of at least one benzoxazinone of formula (I) to act on plants, their seed, and/or their habitat.

Abstract: The present invention relates to protoporphyrinogen IX oxidase (PPO) inhibitors of the general formula (I) where the variables are defined herein. The invention features processes and intermediates for preparing the compounds of formula (I), compositions comprising them, and their use as herbicides—e.g., for controlling harmful plants. The invention also features methods for controlling unwanted vegetation comprising allowing an herbicidal effective amount of at least one PPO inhibitor of formula (I) to act on plants, their seed, and/or their habitat.