Abstract: Gaming systems and methods that provide a symbol display accumulation sequence and a related accumulated symbol display use sequence, wherein the accumulation sequence includes an accumulation of symbol displays during one or more plays of one or more games during, and wherein the use sequence includes the use of the accumulated symbol displays.

Abstract: Lenses and methods are provided for improving peripheral and central vision for patients. The lenses improve vision by having an optic configured to provide optimal peripheral vision that minimizes off-axis astigmatism at, for example, 20 degree eccentricity, while maximizing on-axis visual acuity and contrast sensitivity. The method provides for the design of an IOL that reduces optical errors in an image produced at a peripheral retinal location of a patient's eye disposed at a distance from the fovea, while maximizing on-axis visual acuity and contrast sensitivity.

Abstract: Systems and methods for generating plans are disclosed, where each plan includes actions to achieve goals. An indication to add a goal is received, and a track is displayed representing the goal. For the goal, data describing the goal is received. An input is received to add a node to the track, the node representing an action or area of interest associated with the goal. Within the track, an indication of the node is displayed. One or more node characteristics can be determined and displayed. Additionally or alternatively, a resource may be associated with the node. Using the goal, the data describing the goal, the node, the node characteristics, and/or the resources, the plan is generated. The plan can be output, such as by displaying the plan in a graphical user interface.

Abstract: An apparatus includes solar panels. The apparatus includes a battery system. The top surface of the battery system attaches to a bottom surface of the solar panels, and a bottom surface of the battery system has blocks that fit through apertures within the grooves of a dumpster lid. The apparatus includes a sensor system. The sensor system is attached to a bottom surface of the battery system, and a top surface of the sensor system has a corrugated design that fits into the bottom surface of the battery system. The apparatus includes a microprocessor. The microprocessor sends electronic information to a computing device. The electronic information includes one or more electronic images, and distance information between a top surface of garbage within a dumpster and a bottom surface of the sensor system.

Abstract: The disclosure provides antibody agents that bind to a Lymphocyte Activation Gene-3 (LAG-3) protein. Particular immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide sequences are explicitly provided. Also provided are related nucleic acids, vectors, compositions, and methods of using anti-LAG-3 antibody agents to treat a disorder or disease that is responsive to LAG-3 inhibition, such as, for example, cancer or an infectious disease.

Abstract: An apparatus, comprising a camera, a motion sensor, a receiving section, gas tanks, a screen, and a computing device. The computing device is configured to control the camera to take electronic images, determine a type of food placed in a particular container, determine an amount of gas and a type of gas to fill the particular container, generate an electronic message to request placement of the particular container onto the receiving section, and inject gas into the particular container when the particular container is placed onto the receiving section. The injected gas is used to preserve food inside the container.

Abstract: The present invention provides methods of administering certain PD-1 binding agents to patients having cancer. Dosage regimens for compositions comprising a PD-1 binding agent are also explicitly provided.

Abstract: An oil field chemical-carrying material comprising polymeric particles and a process for making the same are disclosed. An oil field chemical is integrally incorporated into the granulated particle. The oil field chemical is in particular a tracer and the particle is in particular a proppant for use in hydraulic fracturing of a subterranean formation. Methods of delivering oil field chemicals, methods of monitoring subterranean formations, methods of tracing flow of fluid from hydrocarbon reservoirs and methods of hydraulic fracturing subterranean formations are also disclosed.

Abstract: The present invention provides methods of administering certain PD-1 binding agents to patients having cancer. Dosage regimens for compositions comprising a PD-1 binding agent are also explicitly provided.

Abstract: The disclosure provides antibody agents that bind to a Lymphocyte Activation Gene-3 (LAG-3) protein. Particular immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide sequences are explicitly provided. Also provided are related nucleic acids, vectors, compositions, and methods of using anti-LAG-3 antibody agents to treat a disorder or disease that is responsive to LAG-3 inhibition, such as, for example, cancer or an infectious disease.

Abstract: An oil field chemical-carrying material comprising polymeric particles and a process for making the same are disclosed. An oil field chemical is integrally incorporated into the granulated particle. The oil field chemical is in particular a tracer and the particle is in particular a proppant for use in hydraulic fracturing of a subterranean formation. Methods of delivering oil field chemicals, methods of monitoring subterranean formations, methods of tracing flow of fluid from hydrocarbon reservoirs and methods of hydraulic fracturing subterranean formations are also disclosed.

Abstract: A charged particle detector is provided. The charged particle detector includes a flexible semiconductor wafer, the semiconductor wafer being doped to form a p-n junction, and an amplifier coupled to the semiconductor wafer and configured to amplify a current or voltage across the p-n junction.

Abstract: The present invention relates to a method and apparatus for detecting radioactivity. In particular, but not exclusively, the present invention relates to the detection of radioactivity in a target fluid in a fluid communication passageway using a region of scintillator material (130) to provide light responsive to the presence of radioactive material and at least one silicon photomultiplier (SiPM) (150) for providing an output signal responsive to the light provided by the scintillator material.

Abstract: Various embodiments enable an introducer for a catheter to be rotated around an axis and/or traversed backward and/or forward along the axis. In various embodiments, positioning of an introducer may be enabled by an introducer support configured to be rotated around an axis and/or extended or retracted along the axis. The introducer may be manually operated and/or operated by motors in a nose cone of a catheter positioning system. In various embodiments, a portion of the introducer support may be configured to flex. In other embodiment, positioning of an introducer may be enabled by an adjustable nose cone of a catheter positioning system.

Abstract: Various embodiments include a catheter positioning device that may include a sled member, a sled base, an active damping system, a sensor, and a control system. The sled member may be configured to accept a handle of a catheter. The sled base may be configured to move the sled member along a length of the sled base for positioning the catheter within a patient. The active damping system may be configured to apply a force to the sled base to resist movement of the sled base in response to a control signal. The sensor may be configured to generate signals in response to a movement of the sled base. The control system may be configured to receive sensor signals from the sensor and transmit control signals to cause the active damping system to apply the force to resist movement of the sled base indicated in the received sensor signals.

Abstract: A process for cross-linking siloxane and organic polymers comprising reacting (a) a silyl hydride with (b) an unsaturated polymeric compound in the presence of (d) a platinum diene compound with a chelating dianionic ligand.

Abstract: The present disclosure relates to antibodies or fragments thereof that target at least one conformational epitope of a Notch 3 or mutant Notch 3 receptor; and compositions and methods of use thereof.

Abstract: The present invention relates to anti-FGFR2 antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.

Abstract: The present invention relates to LRP6 constructs that bind to LRP6 receptor. The LRP6 constructs comprise at least one LRP6 binding moiety and a half-life extender molecule such that the LRP6 construct inhibit the Wnt signaling pathway without potentiation of the Wnt signal. The LRP6 constructs also have an increased half-life to provide more time for the therapeutic benefit.