Abstract: The present invention provides a system comprising PoE apparatus including midspans, switches and routers that can provide high powered PoE connections that enable the recovery of DC power in sufficient quantities that allow it to be converted to AC power by way of an inverter. The invention also provides a method for providing AC power, data and light to office workstations using a single PoE connection. The invention further comprises a common mode signalling system that operates independently of any TCP/IP signal transmitted through an Ethernet connection wherein said signalling system is adapted to communicate with and control PoE powered devices.

Abstract: A sensor assembly has a housing for mounting on a shaft of an idler roller in a belt conveyor system. The housing has one or more sensors for detecting one or more parameters of the idler roller and a processor in communication with the sensors and a wireless communication device. The sensors transmit the detected parameter data to the processor, which causes the detected parameter data to be transmitted by the wireless communication device. A monitoring system is also provided.

Abstract: The present invention provides a system comprising PoE apparatus including midspans, switches and routers that can provide high powered PoE connections that enable the recovery of DC power in sufficient quantities that allow it to be converted to AC power by way of an inverter. The invention also provides a method for providing AC power, data and light to office workstations using a single PoE connection. The invention further comprises a common mode signalling system that operates independently of any TCP/IP signal transmitted through an Ethernet connection wherein said signalling system is adapted to communicate with and control PoE powered devices.

Abstract: A delivery system, including a polymeric material for storing molecules and/or particles wherein the molecules and/or particles are substantially bound to said polymeric material through: the polymeric material comprising an electrical charge and the molecules and/or particles comprising an electrical charge opposite to the electrical charge of the polymeric material; and/or the molecules and/or particles being physically trapped within pores of the polymeric material; and an ultrasonic transducer configured to apply an ultrasonic signal to the polymeric material to release the molecules and/or particles and to transport the released molecules and/or particles through the polymeric material to a surface for delivery to an entity.

Abstract: A delivery system, including: a material for storing molecules and/or nanoparticles by substantially binding said molecules and/or nanoparticles to said material; a means for applying an electric field to said material to release said molecules and/or nanoparticles; and a means for applying an ultrasonic signal to said material to transport said molecules and/or nanoparticles through said material to a surface for delivery to an entity.

Abstract: An apparatus for disintegration (or mixing) of a solid in a receptacle containing liquid, has a control unit and an ultrasound transducer generating ultrasonic energy under control of the control unit. An annular coupling element in communication with the ultrasound transducer is adapted to receive the receptacle. Ultrasonic energy is transferred to the receptacle contents through the annular coupling element. In use, the ultrasonic energy transferred to the receptacle contents causes disintegration of the solid into the liquid. A method for disintegration of a solid in a receptacle is also described.

Abstract: An apparatus for disintegration (or mixing) of a solid in a vessel containing liquid, has a control unit and an ultrasound transducer for generating ultrasonic energy under control of the control unit. A coupling medium in communication with the ultrasound transducer is adapted to receive the vessel. Ultrasonic energy is transferred to the contents of the vessel such that in use the ultrasonic energy causes disintegration of the solid into the liquid contained in the vessel. An agitating mechanism is adapted to agitate the disintegrated solid in the liquid contained in the vessel. The agitating mechanism may include a paddle having a coating of flavouring material. A method for disintegration of a solid in a vessel is also disclosed.

Abstract: A container for holding liquid is described. The container defines an inner region inside which liquid is adapted to be held and includes one or more walls for facilitating heating or cooling of the liquid therethrough, the one or more walls being adapted for invagination by a temperature control probe such that the temperature control probe extends into the container without directly contacting contents of the inner region of the container.

Abstract: An apparatus for disintegration (or mixing) of a solid in a receptacle containing liquid, has a control unit and an ultrasound transducer generating ultrasonic energy under control of the control unit. An annular coupling element in communication with the ultrasound transducer is adapted to receive the receptacle. Ultrasonic energy is transferred to the receptacle contents through the annular coupling element. In use, the ultrasonic energy transferred to the receptacle contents causes disintegration of the solid into the liquid. A method for disintegration of a solid in a receptacle is also described.

Abstract: A delivery system, including: a material for storing molecules and/or nanoparticles by substantially binding said molecules and/or nanoparticles to said material; a means for applying an electric field to said material to release said molecules and/or nanoparticles; and a means for applying an ultrasonic signal to said material to transport said molecules and/or nanoparticles through said material to a surface for delivery to an entity.

Abstract: A container for holding liquid is described. The container defines an inner region inside which liquid is adapted to be held and includes one or more walls for facilitating heating or cooling of the liquid therethrough, the one or more walls being adapted for invagination by a temperature control probe such that the temperature control probe extends into the container without directly contacting contents of the inner region of the container.

Abstract: A delivery system, including: a material for storing molecules and/or nanoparticles by substantially binding said molecules and/or nanoparticles to said material; means for applying an electric field to said material to release said molecules and/or nanoparticles; and means for applying an ultrasonic signal to said material to transport said molecules and/or nanoparticles through said material to a surface for delivery to an entity.

Abstract: Compounds according to formula (I) wherein n is 0-3, R1 is optionally substituted C1-6 alkyl, C2-6 alkenyl, or C2-6 alkynyl, Heterocycle, Aromatic heterocycle, Aryl or hydrogen and R2, R3, R4, R5, R6, R7, R8 and R9 are each independently selected from hydrogen and optionally substituted C1-6 alkyl, or R5 and R8 are an alkylene chain, are novel.

Abstract: Compounds according to formula (I) wherein n is 0-3, R′ is optionally substituted C1-6 alkyl, C2-6 alkenyl, or C2-6 alkynyl, Heterocycle, Aromatic heterocycle, Aryl or hydrogen and R2, R3, R4, R5, R6, R7, R8 and R9 are each independently selected from hydrogen and optionally substituted C1-6 alkyl, or R5 and R8 are an alkylene chain, are novel. They are useful in the treatment of thrombotic conditions and other pathologies associated with fibrin deposition.

Abstract: An assay method for determining binding of a test compound to pyruvate dehydrogenase kinase (PDHK) at a given site comprising determining (a) the degree of polarisation of the light emitted by a PDHK complex formed by contacting in solution a known concentration of PDHK with a known concentration of a fluorescent compound known to bind to PDHK at that site, and (b) the degree of polarisation of the light emitted by a PDHK complex formed by contacting in solution the test compound, the same concentration of PDHK and the same concentration of the fluorescent compound, a lesser value of the degree of polarisation (b) than that of (a) being taken as indicative of binding of the test compound to that site.

Abstract: Compounds according to formula (I) wherein n is 0-3, R1 is optionally substituted C1-8 alkyl, C2-6 alkenyl, or C2-6 alkynyl, Heterocycle, Aromatic heterocycle, Aryl or hydrogen and R2, R3, R4, R5, R6, R7, R8 and R9 are each independently selected from hydrogen and optionally substituted C1-6 alkyl, or R5 and R8 are an alkylene chain, are novel. They are useful in the treatment of thrombotic conditions and other pathologies associated with fibrin deposition.

Abstract: Compounds according to formula (I) wherein n is 0-3, R1 is optionally substituted C1-6 alkyl, C2-6 alkenyl, or C2-6 alkynyl, Heterocycle, Aromatic heterocycle, Aryl or hydrogen and R2, R3, R4, R5, R6, R7, R8 and R9 are each independently selected from hydrogen and optionally substituted C1-6 alkyl, or R5 and R8 are an alkylene chain, are novel. They are useful in the treatment of thrombotic conditions and other pathologies associated with fibrin deposition.

Abstract: Compounds of the formula: wherein R1, Y, W, A and R2 are as defined above are inhibitors of rotamase enzymes in particular FKBP-12 and FKBP-52. The compounds therefore moderate neuronal regeneration and outgrowth and can be used for treating neurological disorders arising from neurodegenerative diseases and nerve damage.

Abstract: A method and apparatus for monitoring posture deficiencies in the spine and including a flexible body (30) encapsulating a flexible operating arm (31) cantilevered from a base moulding (34). The operating arm (31) is provided with upper (37) and lower (40) strain gauges bonded to the upper and lower faces respectively of the operating arm (31) at the point beyond the stiffening base moulding (34) to ensure that differential strain is experienced on deflection of the operating arm (31). Wire tails (41) are terminated as a PCB assembly (45) mounted to the printed circuit support (35), which assembly comprises a PC board bearing an LSI processor (46), rechargeable battery (47), vibrating motor (50) and inductive coil (51) selected to fulfil the functions of transmitting and receiving element, and inductive power supply for charging the battery (47), under the control of processor (46).

Abstract: The invention provides compounds of the formula (I) or a pharmaceutically acceptable salt thereof, wherein R is a 5-membered ring heteroaryl group containing 3 or 4 nitrogen heteroatoms which is linked to the quinoxalinedione ring by a ring carbon or nitrogen atom said group being optionally benzo-fused and optionally substituted, including in the benzo-fused portion, by 1 or 2 substituents each independently selected from C1-C4 alkyl, C2-C4 alkenyl, C3-C7 cycloalkyl, halo, hydroxy, C1-C4 alkoxy, C3-C7 cycloalkyloxy, —COOH, C1-C4 alkoxycarbonyl, —CONR3R4, —NR3R4, —S(O)p(C1-C4 alkyl), —SO2NR3R4, aryl, aryloxy, aryl(C1-C4)alkoxy, and het, said C1-C4alkyl being optionally substituted by C3-C7 cycloalkyl, halo, hydroxy, C1-C4 alkoxy, halo(C1C4)alkoxy, C3-C7 cycloalkyloxy, C3-C7 cycloalkyl (C1-C4) alkoxy, —COOH, C1-C4 alkoxycarbonyl, —CONR3R4, —NR3R4,—S(O)p(C1-C4 alkyl), —SO2(aryl), —SO2NR3R4 morpholino, aryl, aryloxy, aryl(C1-C4)