Abstract: Delivery devices for an occlusive implant and method for making and using delivery devices are disclosed. An example delivery device may include a delivery sheath having a proximal region, a distal tip region, and a lumen formed therein. A core wire may be slidably disposed in the lumen. The core wire may include a central shaft, a first region having a first coil assembly disposed along the central shaft, a second region having a second coil assembly disposed along the central shaft, and a distal implant securing region. An occlusive implant may be coupled to the distal implant securing region.

Abstract: An example occlusive implant is disclosed. The example occlusive implant includes an expandable framework configured to shift between a first configuration and an expanded configuration and a fixation member disposed along the expandable framework. The fixation member includes a first engagement portion and an anchor portion. Further, the first engagement portion is designed to be secured to the expandable framework and the anchor portion extends away from an outer surface of the expandable framework.

Abstract: Delivery devices for an occlusive implant and method for making and using delivery devices are disclosed. An example delivery device may include a delivery sheath having a proximal region and a laser cut distal tip region. A reinforcing member may extend along the proximal region. The laser cut distal tip region may have one or more laser cuts formed therein that form a patterned distal section. The patterned distal section may be configured to shift between a delivery configuration and an expanded configuration. A core member may be slidably disposed within the delivery sheath. An occlusive implant may be releasably coupled to the core member.

Abstract: Delivery devices for an occlusive implant and method for making and using delivery devices are disclosed. An example delivery device may include a delivery sheath having a proximal region and a distal tip region. A reinforcing member may extend along the proximal region. The distal tip region may include a grooved distal section. The grooved distal section may be configured to shift between a delivery configuration and an expanded configuration. A core member may be slidably disposed within the delivery sheath. An occlusive implant may be releasably coupled to the core member.

Abstract: Delivery devices for an occlusive implant and method for making and using delivery devices are disclosed. An example delivery device may include a delivery sheath having a proximal region, a garage region, and a distal tip region. The proximal region may have a proximal inner diameter. The garage region may have a garage inner diameter larger than the proximal inner diameter. A reinforcing member may extend along the proximal region, the garage region, or both. A core member may be slidably disposed within the delivery sheath. An occlusive implant releasably coupled to the core member.

Abstract: Delivery devices for an occlusive implant and method for making and using delivery devices are disclosed. An example delivery device may include a delivery sheath having a sheath body and a distal tip region. A tip reinforcing member may be coupled to the distal tip region. The tip reinforcing member may define a plurality of distal arm segments. The distal arm segments are configured to shift between a first configuration and an expanded configuration. A core member may be slidably disposed within the delivery sheath. An occlusive implant may be releasably coupled to the core member.

Abstract: An example occlusive implant is disclosed. The example occlusive implant includes an expandable framework configured to shift between a collapsed configuration and an expanded configuration, an occlusive member disposed along at least a portion of the expandable framework and a sealing member disposed along the occlusive member.

Abstract: A delivery system for an occlusive implant may include a delivery sheath having a delivery lumen extending proximally from a distal end of the delivery sheath, the delivery sheath being formed from a polymeric material, and a core wire slidably disposed within the delivery lumen. The core wire may be configured to releasably engage the occlusive implant. The delivery sheath may include a circumferential ring monolithically formed therewith at the distal end of the delivery sheath and a plurality of longitudinal slots disposed proximal of the circumferential ring. An occlusive implant system may include an occlusive implant configured to shift between a delivery configuration and a deployed configuration, and the delivery system for the occlusive implant. The occlusive implant may be disposed within a distal portion of the delivery lumen in the delivery configuration.

Abstract: An example occlusive implant is disclosed. The example occlusive implant includes an expandable framework configured to shift between a collapsed configuration and an expanded configuration, an occlusive member disposed along at least a portion of the expandable framework and a sealing member disposed along the occlusive member.

Abstract: An implantable medical device such as a left atrial appendage closure (LAAC) device includes an expandable frame that is moveable between a collapsed configuration for delivery and an expanded configuration for deployment. One or more space filling elements that are adapted to facilitate thrombus formation are secured to the expandable frame. An expandable element spans at least part of the expandable frame.

Abstract: An example medical device for occluding the left atrial appendage includes an expandable member having a first end region, a second end region and an inflation cavity. The medical device also includes a plurality of spine members coupled to the expandable member, the plurality of spine members spaced circumferentially around an outer surface of the expandable member. Additionally, the medical device includes a valve member extending at least partially into the inflation cavity, wherein the plurality of spine members are configured to position the medical device within an opening of the left atrial appendage and wherein the expandable member is configured to expand and seal the opening of the left atrial appendage.

Abstract: An example medical device for occluding the left atrial appendage is disclosed. The example medical device for occluding the left atrial appendage includes an expandable member having a first end region, a second end region and an inflation cavity. The example medical device includes at least one fixation member having a first end and a second end coupled to the expandable member. The at least one fixation member is configured to move from a delivery configuration to a deployed configuration in response to an expansion of the expandable member. Additionally, the example medical device includes a valve member extending at least partially into the inflation cavity and the expandable member is configured to expand and seal the opening of the left atrial appendage.

Abstract: An occlusive implant system may include an access device including a handle and an access sheath extending distally therefrom. The access device includes a working lumen extending longitudinally therethrough. A proximal portion of the working lumen defines a garage section and a distal portion of the working lumen extends distally of the garage section. The occlusive implant system may include an occlusive implant device including a delivery sheath configured to be received within the garage section, the delivery sheath having a delivery lumen, a core wire disposed therein, and an occlusive implant releasably attached to the core wire. The garage section has a first inner diameter and the distal portion of the working lumen has a second inner diameter less than the first inner diameter. The delivery sheath has an outer diameter less than the first inner diameter and greater than the second inner diameter.

Abstract: An example occlusive implant is disclosed. The example occlusive implant includes an expandable framework configured to shift between a first configuration and a second expanded configuration, an occlusive member disposed along at least a portion of an outer surface of the expandable framework and a resilient member coupled to the occlusive member. Further, the resilient member is configured to keep the occlusive member taut against an outer surface of the expandable member in both the first configuration and the second configuration.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include an elongate shaft having a proximal end region and a distal end region. A first lumen may be defined in the shaft. A second lumen may be defined in the shaft. The distal end region may include a common lumen region in fluid communication with the first lumen and the second lumen. A deflectable member may be disposed within the shaft. The deflectable member may be designed to shift between a first configuration where the deflectable member directs a first medical device disposed within the common lumen region into the first lumen and a second configuration where the deflectable member allows a second medical device to move between the common lumen region and the second lumen.

Abstract: A medical device for left atrial appendage closure includes a support frame with a proximal collar and a distal collar, where the support frame is actuatable from a first constrained configuration to a second radially expanded configuration. A membrane is disposed on at least a portion of the support frame, and an engagement element is coupled to the distal end region of the support frame. The engagement element extends distally from the support frame and is configured to engage an inner surface of the left atrial appendage and prevent the support frame from sliding along the inner surface of the left atrial appendage during implantation.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include an elongate shaft having a proximal end region and a distal end region. A first lumen may be defined in the shaft. A second lumen may be defined in the shaft. The distal end region may include a common lumen region in fluid communication with the first lumen and the second lumen. A deflectable member may be disposed within the shaft. The deflectable member may be designed to shift between a first configuration where the deflectable member directs a first medical device disposed within the common lumen region into the first lumen and a second configuration where the deflectable member allows a second medical device to move between the common lumen region and the second lumen.

Abstract: An example occlusive implant is disclosed. The example occlusive implant includes an expandable framework configured to shift between a first configuration and an expanded configuration and a fixation member disposed along the expandable framework. The fixation member includes a first engagement portion and an anchor portion. Further, the first engagement portion is designed to be secured to the expandable framework and the anchor portion extends away from an outer surface of the expandable framework.

Abstract: An example medical device for occluding the left atrial appendage is disclosed. The example medical device for occluding the left atrial appendage includes an expandable member having a first end region and a second end region. The expandable member comprises at least one inflation cavity and at least one valve member configured to selectively seal the inflation cavity. A first inflation media may be disposed within the at least one inflation cavity and a second inflation media may be disposed within the at least one inflation cavity. The second inflation media may be different from the first inflation media. The expandable member may be configured to expand and seal the opening of the left atrial appendage.

Abstract: An example medical device delivery system is disclosed. The delivery system includes an inflation shaft having a first lumen, a second lumen and a distal end region, the distal end region including an elongated tip. The delivery system also includes a detachment shaft extending along a portion of the inflation shaft. The delivery system also include a delivery shaft having a proximal end region, a distal end region and a lumen extending therein. The delivery system also includes an occlusive member positioned within at least a portion of the lumen of the delivery shaft, wherein the occlusive member is configured to expand and seal the opening of a left atrial appendage. Further, a portion of the elongated tip is removeably engaged with the occlusive member.