Abstract: Disclosed herein are active agents, compositions containing them, unit dosage forms containing them, and methods of their use, e.g., for treating a metabolic disorder or nonalcoholic fatty liver disease or for modulating a metabolic marker or nonalcoholic fatty liver disease marker.

Abstract: Disclosed are conjugates including a recognition element covalently bonded to or linked through a linker to a payload. The payload is a pharmaceutical agent (e.g., an antineoplastic agent, anti-infective agent, or anti-inflammatory agent) or a diagnostic agent. Also disclosed are methods of using the conjugates.

Abstract: Disclosed herein are disposable devices for measuring sweat having low dead volumes and allowing a quick sensory response. Also disclosed herein are methods of making and using such devices.

Abstract: Porous and microporous parts prepared by additive manufacturing as disclosed herein are useful in medical and non-medical applications. The parts are prepared from a composition containing both a solvent soluble component and a solvent insoluble component. After a part is printed by an additive manufacturing process it is exposed to solvent to extract solvent soluble component away front the printed part, resulting in a part having surface cavities.

Abstract: A battery pack suitable for handheld appliance, the battery pack including a plurality of cells and a circuit board associated with the cells, wherein a power terminal is associated with the circuit board and configured to transmit power to an appliance, in use, the battery pack further including a momentary switch operatively connected to the circuit board and movable between closed and open positions by an actuator wherein, when in the open position the power terminal is configured by the circuit to a power delivery state and, when in the closed position, the power terminal is configured by the circuit to a power disabled state.

Abstract: A system for use in installation of blown fiber for detecting a signal indicative of presence of at least one of a gas flow or an optical fiber at a remote location, comprising a gas vibration detector configured to acoustically couple with an installation duct through which the signal can travel after its generation at the remote location, and a processor arranged to receive an input from the vibration detector and to process the input to identify the signal present within the input; and a sensor for generating the signal upon sensing the presence of at least one of the gas flow or the optical fiber at the remote location. The signal can be provided by a whistle mounted on the remote end of the installation duct. The vibration sensor is typically a microphone.

Abstract: A device for use with a conduit having a first conduit end and a conduit second end, into which conduit a cable can be installed using a flow of air into the first conduit end, the device being suitable for confirming that the flow of air is exiting the second conduit end, the device including a housing, means to enable connection of the device to the second conduit end, a light source, a detector arranged to detect a presence or absence of a light signal, and a light shield, wherein in use, the flow of air entering the device causes the light shield and at least one of the light source or the detector, to move to and to stay at a position relative to the other, permitting the detector to detect detections including one or more of a presence or absence of the light signal, an intensity level of the light signal, a change in the presence or absence of the light signal, or a change in the intensity level of the light signal.

Abstract: A device for use with a conduit having a first conduit end and a conduit second end, into which conduit a cable can be installed using a flow of air into the first conduit end, the device being suitable for confirming that the air is flowing out from the second conduit end. In an embodiment, the device includes a housing, means to enable connection of the device to the second conduit end, a detector arranged to detect an electrical property change, and an actuator for causing an electrical property change detectable by the detector, wherein in use, the air flowing into the device causes the detector and the actuator to move relative to each other, causing an electrical property change detectable by the detector.

Abstract: A magnetically-activatable sheet product is provided comprising a pair of laminated outer sheets at least one of which is provided with a pigment/binder primer coat on its inward facing surface, between which is a magnetic layer comprising magnetically-activatable particles in a binder matrix, the outer sheets having sufficient opacity to mask the appearance of the magnetic layer.

Abstract: A system for use in installation of blown fiber for detecting a signal indicative of presence of at least one of a gas flow or an optical fiber at a remote location, comprising a gas vibration detector configured to acoustically couple with an installation duct through which the signal can travel after its generation at the remote location, and a processor arranged to receive an input from the vibration detector and to process the input to identify the signal present within the input; and a sensor for generating the signal upon sensing the presence of at least one of the gas flow or the optical fiber at the remote location. The signal can be provided by a whistle mounted on the remote end of the installation duct. The vibration sensor is typically a microphone.

Abstract: A device for use with a conduit having a first conduit end and a conduit second end, into which conduit a cable can be installed using a flow of air into the first conduit end, the device being suitable for confirming that the flow of air is exiting the second conduit end, the device including a housing, means to enable connection of the device to the second conduit end, a light source, a detector arranged to detect a presence or absence of a light signal, and a light shield, wherein in use, the flow of air entering the device causes the light shield and at least one of the light source or the detector, to move to and to stay at a position relative to the other, permitting the detector to detect detections including one or more of a presence or absence of the light signal, an intensity level of the light signal, a change in the presence or absence of the light signal, or a change in the intensity level of the light signal.

Abstract: A magnetically-activatable sheet product is provided comprising a pair of laminated outer sheets at least one of which is provided with a pigment/binder primer coat on its inward facing surface, between which is a magnetic layer comprising magnetically-activatable particles in a binder matrix, the outer sheets having sufficient opacity to mask the appearance of the magnetic layer.

Abstract: A device for use with a conduit having a first conduit end and a conduit second end, into which conduit a cable can be installed using a flow of air into the first conduit end, the device being suitable for confirming that the air is flowing out from the second conduit end. In an embodiment, the device includes a housing, means to enable connection of the device to the second conduit end, a detector arranged to detect an electrical property change, and an actuator for causing an electrical property change detectable by the detector, wherein in use, the air flowing into the device causes the detector and the actuator to move relative to each other, causing an electrical property change detectable by the detector.

Abstract: The invention provides an axial flow pump (1) for accurately injecting supernatant liquid (2) from adjacent the liquid surface (3) of a thickening tank (not shown) to dilute liquid in a feedwell (4). The pump (1) includes a cup shaped receiving vessel (5) submerged in the supernatant liquid. The pump also includes a submerged impeller (6) mounted on a rotatable shaft (7) for drawing liquid from the vessel (5) and injecting it into the feedwell (4). The shaft (7) is driven by a motor and associated gearbox (not shown). The pump is responsive to system parameters for adjusting the flow rate of the supernatant liquid.