Abstract: The present disclosure is directed towards an absorbent binder composition that includes a hydrophilic polymer which has the capability of post-application, moisture-induced cross-linking. The absorbent binder composition can include 1) a superabsorbent polymer material which can include at least 15 mass percent monoethylenically unsaturated polymer, such as carboxylic acid, sulphonic acid, or phosphoric acid, or salts thereof, and an acrylate or methacrylate ester that contains an alkoxysilane functionality and 2) a polyvalent metal cation having a valence of at least two. Upon loss of water by evaporation, the alkoxysilane functionality forms a silanol functional group which condenses to form a crosslinked polymer. Upon exposure of the absorbent binder composition to a biological material, such as urine, blood, or feces, the biological material can interact with the polyvalent metal cation and can serve as a catalyst to accelerate the polymer cross-linking and gelation of the polymer.

Abstract: A laminate having health-benefit agents therein is made by particle stabilization within the lamination process. By changing the substrate type (tissue, nonwoven, film) and/or the physical composition and/or attributes of the laminate layers, the release of the health-benefit agents can be controlled. The laminate, sometimes referred to as a liner, may be used in personal absorbent articles such as diapers, feminine pads, bandages, bed pads, and the like.

Abstract: A laminate having health-benefit agents therein is made by particle stabilization within the lamination process. By changing the substrate type (tissue, nonwoven, film) and/or the physical composition and/or attributes of the laminate layers, the release of the health-benefit agents can be controlled. The laminate, sometimes referred to as a liner, may be used in personal absorbent articles such as diapers, feminine pads, bandages, bed pads, and the like.

Abstract: The present invention relates to compositions and absorbent articles including compositions for protecting the skin barrier. The compositions can be applied to the bodyfacing surfaces of absorbent articles so that the compositions come into contact with the skin. The compositions of the invention provide several benefits including prevention and alleviation of skin irritations associated with the use of absorbent articles. The compositions can include hydrophilic and non-aqueous components as well as extracted botanical actives.

Abstract: The present invention relates to MMP regulators that comprise new synthetic peptides, that comprise amino acid sequences structurally similar to those of MMP binding region of TIMPs, coupled to zinc chelators. The invention also relates to methods for making these MMP regulators and their use for the treatment of chronic and acute wounds and for the treatment of angiogenesis-associated diseases.

Abstract: A tampon adapted to deliver a therapeutic agent includes a body having a proximal end and a distal end. The body includes an absorbency zone adjacent the distal end, wherein the absorbency zone includes absorbent material; an application zone adjacent the proximal end and spaced apart from the distal end; and a therapeutic agent positioned substantially within the application zone. A method produces a device for delivering a therapeutic agent. The method includes manufacturing a tampon having a body with a distal end, a proximal end, an absorbency zone adjacent the distal end, and an application zone adjacent the proximal end; and locating a therapeutic agent substantially within the application zone.

Abstract: An absorbent personal care device, such as an interlabial pad, tampon, sanitary pad or liner, or incontinence product adapted to deliver a therapeutic agent to the vaginal epithelium for systemic and topical treatment, the tampon including absorbent material and a formulation including a therapeutic agent, wherein the therapeutic agent is a botanical. The botanical may be, but is not limited to, Agnus castus, aloe vera, comfrey, calendula, dong quai, black cohosh, chamomile, evening primrose, Hypericum perforatum, licorice root, black currant seed oil, St. John's wort, tea extracts, lemon balm, capsicum, rosemary, Areca catechu, mung bean, borage seed oil, witch hazel, fenugreek, lavender, soy, heath, cranberries, blueberries, azaleas, red onion skin, short red bell peppers, long red bell peppers, beet root extract, capsanthin, whortleberry, lingenberry, chokeberry, sweet rowan, rowanberry, seabuckhrouberry, crowberry, strawberries, or gooseberries.

Abstract: The present invention provides fibers, foams, films and nonwoven fabrics having more than one skin treatment benefit and/or improved skin treatment benefit(s) and to products incorporated such fibers, foams, films and fabrics. The present invention also provides a method of forming fibers, nonwoven fabrics, porous films and foams with multiple skin treatment additives that impart a number of skin health attributes.

Abstract: The present invention relates to absorbent articles including non-aqueous compositions for protecting the barrier function of the skin. The compositions can be applied to the bodyfacing surfaces of absorbent articles so that the compositions come into contact with the skin. The compositions of the invention have improved stability on the bodyfacing surfaces after processing. The compositions of the invention provide several benefits including prevention and alleviation of skin irritations associated with the use of absorbent articles. The compositions can include emollients, viscosity enhancers and extracted botanical actives.

Abstract: The present invention relates to compositions and absorbent articles including compositions for protecting the skin barrier. The compositions can be applied to the bodyfacing surfaces of absorbent articles so that the compositions come into contact with the skin. The compositions of the invention provide several benefits including prevention and alleviation of skin irritations associated with the use of absorbent articles. The compositions can include hydrophilic and non-aqueous components as well as extracted botanical actives.

Abstract: The present invention relates to a system for improving the skin health of wearers of absorbent articles. Wet wipes are typically used in conjunction with absorbent articles for cleansing. It has been discovered that non-aqueous skin care compositions are best delivered from a bodyfacing surface of an absorbent article and that hydrophilic skin care solutions are capable of delivering anti-irritants to the skin. It has further been discovered that the combination of an absorbent article having a skin care composition and a wet wipe having a skin care solution provides improved transfer of skin care ingredients to the skin.

Abstract: Sensors for detecting catabolic proteinase enzymes and proenzymes in the fluid of a human or animal and methods for detecting the enzymes and then providing treatment that is specific for the detected enzyme are disclosed. The sensors of the present invention can be used to detect catabolic proteinase enzymes and proenzymes in the fluid of chronic wounds of humans and animals. Upon detection of any proteinase enzyme, the wound can be treated with an inhibiting complex that is specific for the detected enzyme or proenzyme. Enzymes such as matrix metalloproteinases and human neutrophil elastase in the active and proenzyme form can be detected and treatment provided with inhibitors for the detected enzyme.

Abstract: An absorbent device configured for partial disposition within the vestibule of a wearer, and adapted to deliver a therapeutic agent, the device including a fluid-absorbent body having an application region for projection within the vestibule; and a formulation including a therapeutic agent positioned substantially within the application region. Also, a method for producing an absorbent device configured for partial disposition within the vestibule of a wearer, and adapted to deliver a therapeutic agent, the method including manufacturing an absorbent device having a fluid-absorbent body having an application region for projection within the vestibule; and locating a formulation including the therapeutic agent substantially within the application region.

Abstract: An absorbent personal care device, such as an interlabial pad, tampon, sanitary pad or liner, or incontinence product adapted to deliver a therapeutic agent to the vaginal epithelium for systemic and topical treatment, the tampon including absorbent material and a formulation including a therapeutic agent, wherein the therapeutic agent is a botanical. The botanical may be, but is not limited to, Agnus castus, aloe vera, comfrey, calendula, dong quai, black cohosh, chamomile, evening primrose, Hypericum perforatum, licorice root, black currant seed oil, St. John's wort, tea extracts, lemon balm, capsicum, rosemary, Areca catechu, mung bean, borage seed oil, witch hazel, fenugreek, lavender, soy, heath, cranberries, blueberries, azaleas, red onion skin, short red bell peppers, long red bell peppers, beet root extract, capsanthin, whortleberry, lingenberry, chokeberry, sweet rowan, rowanberry, seabuckhrouberry, crowberry, strawberries, or gooseberries.

Abstract: A breast pad assembly is disclosed wherein one face of the breast pad which faces the breast during use contains a composition comprising a skin benefit ingredient for improving the skin health of a woman's breast and nipple skin. In one embodiment of the invention, the skin health benefit ingredient comprises omega-3 fatty acids which can replace lipids lost from the breast and nipple during breast feeding. The omega-3 fatty acids can also be ingested by the infant to improve systemic development in the infant. In another embodiment, the skin benefit ingredient comprises omega-3 fatty acids and essential fatty acids.

Abstract: The present invention relates to a method of sequestering skin irritants with a skin irritant sequestering composition comprising a substrate, a hydrophilic skin irritant sequestering agent and a hydrophobic skin irritant sequestering agent. In one embodiment the sequestering agents are comprised of modified and non-modified clays. The present invention further also provides a method of sequestering skin irritants comprising administering to the stratum corneum of an individual's skin a skin irritant sequestering composition comprising a substrate, a skin irritant sequestering amount of a combination of hydrophilic and hydrophobic skin irritant sequestering agents. In one embodiment the skin irritants are bound to sequestering agents present on a substrate. In another embodiment the skin irritants are bound to sequestering agents present on the skin.

Abstract: The present invention relates to MMP regulators that comprise new synthetic peptides, that comprise amino acid sequences structurally similar to those of MMP binding region of TIMPs, coupled to zinc chelators. The invention also relates to methods for making these MMP regulators and their use for the treatment of chronic and acute wounds and for the treatment of angiogenesis-associated diseases.

Abstract: A tampon is adapted to deliver a therapeutic agent, the tampon including a body having a proximal end and a distal end, the body including an absorbency zone adjacent the distal end, wherein the absorbency zone includes absorbent material; an application zone adjacent the proximal end and spaced apart from the distal end; and a therapeutic agent positioned substantially within the application zone. A method produces a device for delivering a therapeutic agent, the method including manufacturing a tampon having a body with a distal end, a proximal end, an absorbency zone adjacent the distal end, and an application zone adjacent the proximal end; and locating a therapeutic agent substantially within the application zone.

Abstract: The present invention provides a method of sequestering nasal secretion skin irritants comprising administering to the stratum corneum of an individual's skin a facial tissue comprising a tissue substrate, a nasal secretion skin irritant sequestering amount of a combination of hydrophilic and hydrophobic nasal secretion skin irritant sequestering agents. In one embodiment the sequestering agents are comprised of modified and non-modified clays. In one embodiment the skin irritants are bound to sequestering agents present on a substrate. In another embodiment the skin irritants are bound to sequestering agents present on the skin.

Abstract: Facial tissue is provided comprising a tissue substrate, a hydrophilic nasal secretion skin irritant sequestering agent and a hydrophobic nasal secretion skin irritant sequestering agent. In one embodiment the sequestering agents are comprised of modified and non-modified clays. In one embodiment the skin irritants are bound to sequestering agents present on a substrate. In another embodiment the skin irritants are bound to sequestering agents present on the skin.