Patents by Inventor David Joy

David Joy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240420490
    Abstract: Methods and systems described herein may allow for the classification of microglial morphology at single cell resolution. Microglial cell states may be determined, and a biological sample from which the microglial cells are obtained may be classified based on the microglial cell states. Classifying microglial cells may involving segmenting microglia cells into soma and processes in immunofluorescence microscopy images. Additionally, a feature bank may be generated. Values of the features in the feature bank may be measured for an image. Cells may be clustered using the values of the features in the feature bank. The cells in a cluster may be compared to a reference cell with a known state and having known morphological properties. The cluster in the cell may then be assigned the same state as a reference cell. The amount of cells having the state may then be used to determine properties of the biological sample.
    Type: Application
    Filed: October 19, 2022
    Publication date: December 19, 2024
    Applicant: Denali Therapeutics Inc.
    Inventors: Meredith Calvert, David Joy
  • Publication number: 20240295544
    Abstract: Provided herein are methods and compositions useful for identifying compounds that can inhibit SARS-CoV-2 infection or the effects thereof, especially in cardiomyocytes (CMs), which are highly infectible by SARS-CoV-2 corona viruses.
    Type: Application
    Filed: August 24, 2021
    Publication date: September 5, 2024
    Inventors: Todd C. McDevitt, Bruce Conklin, Melanie Ott, Juan Perez-Bermejo, Michael Sungwon Kang, Sarah Rockwood, Camille Simoneau, Gokul Ramadoss, David Joy
  • Publication number: 20070100931
    Abstract: A distributed managed system including targets, clients, and a management processor. Each client is adapted to originate commands with at least some commands having a desired destination of one or more targets. The management processor is adapted to receive commands originated by the clients and generate a context value for each received command having a desired destination. The context value indicates a particular client that originated the command. The management processor adds the context value to each corresponding command to create commands with context and dispatches commands with context to the desired destination. At least one target is adapted to receive the commands with context, interpret the context value to identify the particular client that originated the command, and process the commands with context.
    Type: Application
    Filed: October 28, 2005
    Publication date: May 3, 2007
    Inventors: Keith Kinnan, Darren Cepulis, Jeffrey Hilland, David Joy