Patents by Inventor David K. Male

David K. Male has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoparticle delivery compositions
    Patent number: 10300022
    Abstract: Nanoparticle delivery systems for use in targeting biologically active agents to the central nervous system comprise a composition comprising (a) a nanoparticle comprising: (i) a core comprising a metal and/or a semiconductor; and (ii) a corona comprising a plurality of ligands covalently linked to the core, wherein said ligands comprise a carbohydrate, insulin and/or a glutathione; and (b) the at least one agent to be delivered to the CNS. Methods of treatment and diagnosing CNS disorders utilizing the nanoparticle delivery systems and related screening methods are also disclosed.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: May 28, 2019
    Assignee: Midatech Ltd.
    Inventors: Thomas Rademacher, David K. Male
  • NANOPARTICLE DELIVERY COMPOSITIONS
    Publication number: 20140227186
    Abstract: Nanoparticle delivery systems for use in targeting biologically active agents to the central nervous system comprise a composition comprising (a) a nanoparticle comprising: (i) a core comprising a metal and/or a semiconductor; and (ii) a corona comprising a plurality of ligands covalently linked to the core, wherein said ligands comprise a carbohydrate, insulin and/or a glutathione; and (b) the at least one agent to be delivered to the CNS. Methods of treatment and diagnosing CNS disorders utilising the nanoparticle delivery systems and related screening methods are also disclosed.
    Type: Application
    Filed: February 7, 2014
    Publication date: August 14, 2014
    Inventors: Thomas Rademacher, David K. Male