Patents by Inventor David K. Miller

David K. Miller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240115701
    Abstract: Provided herein are methods of separating host cell lipases from a production protein in chromatographic processes and methods of improving polysorbate-80 stability in a production protein formulation by separating host cell lipases from the production protein using chromatographic processes. Also provided herein are compositions comprising antibodies or antigen binding fragments thereof that bind to cytotoxic T lymphocyte associated antigen 4 (CTLA4). In another aspect, such compositions further comprise a reduced level of host cell proteins and/or increased level of polysorbate-80 (PS-80) stability.
    Type: Application
    Filed: September 18, 2020
    Publication date: April 11, 2024
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Rebecca A. Chmielowski, Francis K. Insaidoo, Justin B. Miller, David J. Roush, Darshini Shah, John P. Welsh
  • Patent number: 5344023
    Abstract: A three piece egg container assembly is provided which includes a rectangular base member having a bottom wall, sidewalls and an open top, an egg tray with a plurality of egg receiving receptacles receivable within the base member and a removable lid for the base member. The lid is configured with a peripheral lip such that one side of the lid conforms to the base member bottom wall, the open top of the base member and the egg tray such that the first surface of the lid could receive any of those elements. A second side of the lid conforms to the opening of the base member such that the lid can be received in the opening either in an upright position or an inverted position. Stacking of numerous base members with intervening inverted lids or stacking of the egg tray on the lid is thereby accommodated by this construction.
    Type: Grant
    Filed: December 30, 1993
    Date of Patent: September 6, 1994
    Assignee: Whirlpool Corporation
    Inventors: Patricia A. Cox, David K. Miller
  • Patent number: 4490784
    Abstract: A high-speed data transfer unit that transfers data between a central processing unit in a data processing system and an external device such as a disk drive. The transfer unit has two control units, one that controls transfers with the central processing unit under control of port control commands from the processor, and the other that controls transfers with the external device under control of operational commands.
    Type: Grant
    Filed: April 21, 1982
    Date of Patent: December 25, 1984
    Inventors: David C. Ives, David K. Miller, Simon Steely, Jr.
  • Patent number: 4435810
    Abstract: A self-supporting laser diffuser flow energizer is described for improving the performance of radial flow lasers by providing novel means for pressure recovery, and comprises a self-sustaining suction means communicating with the laser cavity for changing the supersonic shock front configuration existing within a radial laser diffuser and thereby promoting the flow of gaseous laser medium within the laser cavity.
    Type: Grant
    Filed: September 10, 1981
    Date of Patent: March 6, 1984
    Assignee: The United States of America as represented by the Secretary of the Air Force
    Inventors: Siegfried H. Hasinger, James M. Howard, David K. Miller
  • Patent number: 4058141
    Abstract: A supersonic diffuser having a plurality of blades therein for dividing the diffuser channel into a plurality of approximately axisymmetric ducts wherein a portion of said ducts ingest a boundary layer along at least one of the walls of the supersonic diffuser. The blades in the diffuser channel have their upstream ends bent away from the wall having the boundary layer to redirect the flow into the ducts. In one embodiment the wall between the duct having the boundary layer and the duct adjacent to the duct having the boundary layer is made in two sections with both sections being bent away from the wall having the boundary layer, to provide internal redistribution between the two ducts.
    Type: Grant
    Filed: July 19, 1976
    Date of Patent: November 15, 1977
    Assignee: The United States of America as represented by the Secretary of the Air Force
    Inventors: Siegfried H. Hasinger, David K. Miller