Patents by Inventor David K.Y Poon

David K.Y Poon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES WITH ENHANCED OR SUPPRESSED EFFECTOR FUNCTION
    Publication number: 20160159921
    Abstract: Rationally designed antibodies and polypeptides that comprise multiple Fc region amino acid substitutions that synergistically provide enhanced selectivity and binding affinity to a target Fc receptor are provided. The polypeptides are mutated at multiple positions to make them more effective when incorporated in antibody therapeutics than those having wild-type Fc components.
    Type: Application
    Filed: February 17, 2016
    Publication date: June 9, 2016
    Inventors: Igor D'Angelo, Dustin Bleile, Stacey A.L. Tom-Yew, Eric Escobar-Cabrera, Paula I. Lario, Anders Ohrn, David K.Y. Poon, Surjit B. Dixit
  • Antibodies with enhanced or suppressed effector function
    Patent number: 9296815
    Abstract: Rationally designed antibodies and polypeptides that comprise multiple Fc region amino acid substitutions that synergistically provide enhanced selectivity and binding affinity to a target Fc receptor are provided. The polypeptides are mutated at multiple positions to make them more effective when incorporated in antibody therapeutics than those having wild-type Fc components.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: March 29, 2016
    Assignee: Zymeworks Inc.
    Inventors: Igor D'Angelo, Dustin Bleile, Stacey A. L. Tom-Yew, Eric Escobar-Cabrera, Paula I. Lario, Anders Ohrn, David K. Y. Poon, Surjit B. Dixit
  • Antibodies with Enhanced or Suppressed Effector Function
    Publication number: 20130108623
    Abstract: Rationally designed antibodies and polypeptides that comprise two Fc region amino acid substitutions that synergistically provide enhanced selectivity and binding affinity to a target Fc receptor are provided. The polypeptides comprise Fc region mutations at two positions that synergistically make the polypeptides more effective when incorporated in antibody therapeutics than those having wild-type Fc components.
    Type: Application
    Filed: March 28, 2011
    Publication date: May 2, 2013
    Applicant: ZYMEWORKS INC
    Inventors: Igor D'Angelo, Dustin Bleile, Stacey A.L. Tom-Yew, Eric Escobar-Cabrera, Paula I. Lario, Anders Ohrn, David K.Y. Poon, Surjit B. Dixit
  • Antibodies with Enhanced or Suppressed Effector Function
    Publication number: 20130089541
    Abstract: Rationally designed antibodies and polypeptides that comprise multiple Fc region amino acid substitutions that synergistically provide enhanced selectivity and binding affinity to a target Fc receptor are provided. The polypeptides are mutated at multiple positions to make them more effective when incorporated in antibody therapeutics than those having wild-type Fc components.
    Type: Application
    Filed: March 28, 2011
    Publication date: April 11, 2013
    Applicant: ZYMEWORKS INC
    Inventors: Igor D'Angelo, Dustin Bleile, Stacey A.L. Tom-Yew, Eric Escobar-Cabrera, Paula I. Lario, Anders Ohrn, David K.Y Poon, Surjit B. Dixit