Abstract: Provided are combination dosing regimens comprising administering an antibody-drug conjugate and hyaluronidase. Combinations and compositions containing the antibody-drug conjugate and hyaluronidase are provided. The dosing regimens and combinations are for treating or preventing cancer.

Abstract: Systems and methods for mapping a planar surface to a curved surface. One such method comprises providing a planar lattice pattern having identical regular polygon shapes which can be truss support modules for supporting a curved surface structure. Method further include determining respective positions of the nodal points of the identical polygon shapes by placing a starting nodal point on an axis of symmetry of the planar lattice pattern and iteratively positioning each nodal point in relation to already placed neighboring nodes to make a distance between a currently positioned nodal point optimally close with a set value of the planar lattice pattern. Method still further comprises forming a curved lattice pattern of the truss support module based on the positions of the nodal points of the identical polygon shapes.

Abstract: A system and associated methods for organizing, representing, finding, discovering, and using data. Embodiments represent information and data in the form of a data structure termed a Feature Graph, that includes nodes and edges, where the edges serve to connect a node to one or more other nodes. A node in a Feature Graph may represent a variable, such as a measurable object, characteristic, or factor of a study. An edge in a Feature Graph may represent a measure of a statistical association between a node and one or more other nodes. Datasets that demonstrate or support the statistical association or measure the associated variable may be accessed through an identifier in a Feature Graph. An application may traverse a Feature Graph and aggregate and process data associated with a set of nodes or edges.

Abstract: Systems and methods for improving the accuracy of information obtained using a large language model. In one embodiment, this involves augmenting the capabilities of a graph generated from unstructured data with information from an external source using Retrieval Augmented Generation (RAG). In one embodiment, expert knowledge is used to review clustering and cluster summarizations derived from the results of a search over the graph data and information prior to application of RAG to generate additional information to augment the search results.

Abstract: A system and associated methods for organizing, representing, finding, discovering, and using data. Embodiments represent information and data in the form of a data structure termed a Feature Graph, that includes nodes and edges, where the edges serve to connect a node to one or more other nodes. A node in a Feature Graph may represent a variable, such as a measurable object, characteristic, or factor of a study. An edge in a Feature Graph may represent a measure of a statistical association between a node and one or more other nodes. Datasets that demonstrate or support the statistical association or measure the associated variable may be accessed through an identifier in a Feature Graph. An application may traverse a Feature Graph and aggregate and process data associated with a set of nodes or edges.

Abstract: An integrated circuit includes a set of N unit analog-to-digital converters (ADCs) having a common architecture, and which provide an aggregate data rate. Moreover, the integrated circuit includes control logic that selects subsets of the set of N unit ADCs in order to realize sub-ADCs of different data rates that can each be an arbitrary integer multiple of an inverse of N times the aggregate data rate of the N unit ADCs. Furthermore, the control logic may dynamically select the subsets on the fly or on a frame-by-frame basis. This dynamically selection may occur at boot time and/or a runtime. Additionally, the given different data rate may correspond to one or more phases of a multi-phase clock in the integrated circuit, where the multiphase clock may include a number of phases corresponding to a number of possible subsets, and given selected subsets may not use all of the available phases.

Abstract: An integrated circuit includes a set of N unit analog-to-digital converters (ADCs) having a common architecture, and which provide an aggregate data rate. Moreover, the integrated circuit includes control logic that selects subsets of the set of N unit ADCs in order to realize sub-ADCs of different data rates that can each be an arbitrary integer multiple of an inverse of N times the aggregate data rate of the N unit ADCs. Furthermore, the control logic may dynamically select the subsets on the fly or on a frame-by-frame basis. This dynamically selection may occur at boot time and/or a runtime. Additionally, the given different data rate may correspond to one or more phases of a multi-phase clock in the integrated circuit, where the multiphase clock may include a number of phases corresponding to a number of possible subsets, and given selected subsets may not use all of the available phases.

Abstract: Embodiments disclosed herein generally relate to a system and method for personalization of advertisement content. A computing system receives an HTTP request to access a webpage. The HTTP request includes a visitor identifier. The computing system parses the HTTP request to identify the visitor identifier contained therein. The computing system transfers the visitor identifier to a remote advertisement server. The computing system receives an advertisement call from a web browser executing on the remote computing system. The advertisement call includes the visitor identifier. The computing system generates a customized advertisement based at least on content accessed by the remote computing system on the webpage. The computing system transmits the customized advertisement to the web browser for display with the website on the remote computing system. The website is hosted by the third-party web server.

Abstract: A system and methods for improving the ability of a business or other entity to monitor business related metrics (such as KPIs) and the evaluation of the quality of the underlying data used to generate those metrics.

Abstract: An integrated circuit includes a set of N unit analog-to-digital converters (ADCs) having a common architecture, and which provide an aggregate data rate. Moreover, the integrated circuit includes control logic that selects subsets of the set of N unit ADCs in order to realize sub-ADCs of different data rates that can each be an arbitrary integer multiple of an inverse of N times the aggregate data rate of the N unit ADCs. Furthermore, the control logic may dynamically select the subsets on the fly or on a frame-by-frame basis. This dynamically selection may occur at boot time and/or a runtime. Additionally, the given different data rate may correspond to one or more phases of a multi-phase clock in the integrated circuit, where the multiphase clock may include a number of phases corresponding to a number of possible subsets, and given selected subsets may not use all of the available phases.

Abstract: A system and associated methods for organizing, representing, finding, discovering, and using data. Embodiments represent information and data in the form of a data structure termed a Feature Graph, that includes nodes and edges, where the edges serve to connect a node to one or more other nodes. A node in a Feature Graph may represent a variable, such as a measurable object, characteristic, or factor of a study. An edge in a Feature Graph may represent a measure of a statistical association between a node and one or more other nodes. Datasets that demonstrate or support the statistical association or measure the associated variable may be accessed through an identifier in a Feature Graph. An application may traverse a Feature Graph and aggregate and process data associated with a set of nodes or edges.

Abstract: An integrated circuit includes a set of N unit analog-to-digital converters (ADCs) having a common architecture, and which provide an aggregate data rate. Moreover, the integrated circuit includes control logic that selects subsets of the set of N unit ADCs in order to realize sub-ADCs of different data rates that can each be an arbitrary integer multiple of an inverse of N times the aggregate data rate of the N unit ADCs. Furthermore, the control logic may dynamically select the subsets on the fly or on a frame-by-frame basis. This dynamically selection may occur at boot time and/or a runtime. Additionally, the given different data rate may correspond to one or more phases of a multi-phase clock in the integrated circuit, where the multiphase clock may include a number of phases corresponding to a number of possible subsets, and given selected subsets may not use all of the available phases.

Abstract: An integrated circuit includes a set of N unit analog-to-digital converters (ADCs) having a common architecture, and which provide an aggregate data rate. Moreover, the integrated circuit includes control logic that selects subsets of the set of N unit ADCs in order to realize sub-ADCs of different data rates that can each be an arbitrary integer multiple of an inverse of N times the aggregate data rate of the N unit ADCs. Furthermore, the control logic may dynamically select the subsets on the fly or on a frame-by-frame basis. This dynamically selection may occur at boot time and/or a runtime. Additionally, the given different data rate may correspond to one or more phases of a multi-phase clock in the integrated circuit, where the multiphase clock may include a number of phases corresponding to a number of possible subsets, and given selected subsets may not use all of the available phases.

Abstract: The present disclosure describes systems and methods for mapping a planar surface to a curved surface. One such method comprises providing a planar lattice pattern having identical regular polygon shapes which can be truss support modules for supporting a curved surface structure. Method further include determining respective positions of the nodal points of the identical polygon shapes by placing a starting nodal point on an axis of symmetry of the planar lattice pattern and iteratively positioning each nodal point in relation to already placed neighboring nodes to make a distance between a currently positioned nodal point optimally close with a set value of the planar lattice pattern. Method still further comprises forming a curved lattice pattern of the truss support module based on the positions of the nodal points of the identical polygon shapes.

Abstract: The seam welder conductive mechanism is the main part of the resistance seam welding machine. When the electrode wheel rolling on the welded parts, the Seam welder conductive mechanism will withstand the high press of electrode force and pass the high welding current from welding transformer to the electrode wheels of seam welding machine. Because of these two characteristics the following factors must be considered during the design of seam welder conductive mechanism. First of all, in order to withstand the high press of electrode force two bearings are introduced in the mechanism, the bearing should be lubricated and also isolated from the welding current in order to get long working time without damaging the bearing. Second of all, in order to pass the high welding current, the conductive pair with relative motion must be keep conduction all the time with certain surface pressure and lubrication, the conductive pair without relative motion must be keep conduction all the time with big surface pressure.

Abstract: Embodiments disclosed herein generally relate to a system and method for personalization of advertisement content. A computing system receives an HTTP request to access a webpage. The HTTP request includes a visitor identifier. The computing system parses the HTTP request to identify the visitor identifier contained therein. The computing system transfers the visitor identifier to a remote advertisement server. The computing system receives an advertisement call from a web browser executing on the remote computing system. The advertisement call includes the visitor identifier. The computing system generates a customized advertisement based at least on content accessed by the remote computing system on the webpage. The computing system transmits the customized advertisement to the web browser for display with the website on the remote computing system. The website is hosted by the third-party web server.

Abstract: The present invention provides infusion devices and methods for subcutaneous delivery of high viscosity fluids. The devices and methods described are innovative subcutaneous infusion systems that allow for the rapid delivery of viscous therapeutic fluids while avoiding adverse side effects and promoting patient comfort. The devices and methods described are also useful for rapid delivery of high volumes of therapeutic fluids.

Abstract: A system for detecting the envelope of a signal is provided. The system includes a first envelope detector generating a first envelope signal of an input RF signal, such as an envelope signal representing the positive peak envelope of the input RF signal. A second envelope detector generates a second envelope signal of the input RF signal, such as an envelope signal representing the negative peak envelope of the input RF signal. A signal combiner receives the first envelope signal and the second envelope signal and generates an even-order harmonic compensated envelope signal, such as by compensating for the difference between the positive peak envelope and the negative peak envelope.

Abstract: A fully-integrated tuner for performing signal channel selection and image rejection in an analog cable television system is provided. Various embodiments disclose a tuner including an analog RF section to process an analog RF input signal and generate complex low intermediate frequency digital signals, and a signal processing section configured to reduce image and signal leakage in the complex low intermediate frequency signals. The signal processing section selects a signal channel of the complex low intermediate frequency signals and suppresses channel components adjacent to the signal channel. In one embodiment, the signal processing section includes a complex digital signal channel select filter to select the signal channel and suppress the adjacent channel components. In other embodiments, the complex digital signal channel select filter selects the signal channel, shapes the selected signal channel to generate a shaped signal channel, and equalizes a group delay of the shaped signal channel.

Abstract: A tuner and demodulator performing image rejection in an analog cable television system. Various embodiments disclose a tuner including an analog RF section to generate a complex intermediate frequency digital signal, an image rejection module configured to perform image rejection on the complex intermediate frequency digital signal to generate an enhanced image rejection signal, a signal channel select filter configured to perform digital on-chip filtering on the enhanced image rejection signal to generate a filtered signal, and a demodulator configured to demodulate the filtered signal to generate digital output signals. In some embodiments, the tuner is substantially or fully monolithic. In some embodiments, the tuner performs image rejection by applying an algorithm to estimate a signal correlation between the signal band and the image band of the complex intermediate frequency digital signal, and providing adaptive filtering to reduce signal leakage and image leakage.