Abstract: The present invention provides animal cells that have been engineered to express one or more viral antigens. The engineered cells can be formulated into cultured meat products that can be used as edible vaccines.

Abstract: Restricting peripheral device protocols in confidential compute architectures, the method including: receiving a first address translation request from a peripheral device supporting a first protocol, wherein the first protocol supports cache coherency between the peripheral device and a processor cache; determining that a confidential compute architecture is enabled; and providing, in response to the first address translation request, a response including an indication to the peripheral device to not use the first protocol.

Abstract: Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial entities, are described herein. The probiotic compositions may optionally contain or be used in conjunction with one or more prebiotics. Uses of the probiotic compositions to treat or prevent disorders of the local or systemic microbiome in a subject are also provided.

Abstract: The disclosure relates to pheromone extracts from nematode growth medium, and methods of using such nematode extracts to increase the abundance of fungal and bacterial microbials in the soil to promote plant growth, plant health, and to protect plants from environmental stresses including abiotic and biotics stresses.

Abstract: The present disclosure provides binding agents that modulate the interaction between liver-expressed antimicrobial peptide 2 (LEAP2) and growth hormone secretagogue receptor (GHSR). Specifically, the present disclosure provides binding agents, such as LEAP2 peptides that bind GHSR and methods of their use to treat or ameliorate a neuroendocrine and/or metabolic disease or disorder such as obesity, diabetes, acromegaly, gigantism and/or Prader-Willi syndrome. The present disclosure also provides binding agents, such as antibodies, that bind LEAP2, and methods of their use to, e.g., treat or ameliorate a neuroendocrine and/or metabolic disease or disorder such as cachexia, anorexia, or other wasting syndromes, increase growth hormone levels, or increase GHSR activity.

Abstract: Gasket assemblies and related system and methods. An apparatus includes a system, a flow cell, and a plurality of gasket assemblies. The system includes a flow cell interface and the flow cell has one or more channels. Each channel has a first channel opening and a second channel opening. The first channel openings are positioned at a first end of the flow cell and the second channel openings are positioned at a second end of the flow cell. A gasket assembly coupled at each second channel opening. Each gasket assembly includes an adhesive stack and a gasket. The adhesive stack includes a first side bonded to the gasket and a second side bonded to the flow cell. The flow cell interface is engagable with the corresponding gaskets to establish a fluidic coupling between system and the flow cell.

Abstract: Disclosed herein are biopolymer-based coatings and products incorporating such coatings. Related methods and use are also provided.

Abstract: A method for generating three dimensional indicators for the visually impaired. The method includes selecting one or more pre-designed symbols from a plurality of pre-designed symbols. The pre-designed symbols represent standard building layout features and are sized to be readable via a physical touch. The method further includes inserting the one or more selected symbols into a two dimensional digital layout, and generating one or more of an orientation object and a legend object into the two dimensional digital layout. The method further includes converting the two dimensional digital layout into a three dimensional digital model, and generating an output file including the three dimensional model in a format compatible with a three dimensional printing device.

Abstract: A computing system may implement a split random number generator that may use a random number generator to generate and store seed values in a memory for retrieval and use by one or more core processors to generate random numbers for secure processes within each core processor.

Abstract: The disclosed system provides an adaptive control system technique generally related to distributed energy resources (DERs) located in distribution circuits. More specifically, the system technique relates to a DER with both active and reactive generation capability. In an embodiment, the system measures a voltage phase angle and a current phase angle of distribution feeder circuit, and measures a voltage value output by a power converter. The system calculates an active power setpoint value and a reactive power setpoint value of the power converter based on the measured voltage value, and the measured voltage phase angle and current phase angle. The system then sets the active and reactive power setpoint values on the power converter. The disclosed system automatically adjusts the setpoints to real-time load characteristics of the distribution feeder circuit, increases distribution feeder hosting capacity, and enables DERs to integrate in distribution feeders more efficiently.

Abstract: In some embodiments, the present invention provides methods for making resorbable ear tubes including the steps of providing a silk fibroin solution, and forming a silk ear tube from the silk fibroin solution, wherein the silk ear tube is less than 2 mm in length and has an outer diameter of less than 1.5 mm, and wherein the silk ear tube is resorbable. In some embodiments, the present invention also provides methods for treating otitis media including the step of introducing a silk ear tube into the ear canal of a subject, wherein the silk ear tube is less than 2 mm in length and has an outer diameter of less than 1.5 mm, and wherein the silk ear tube is resorbed by the subject.

Abstract: A method includes establishing an isolated execution environment for executing a platform firmware operating mode subroutine in a platform firmware operating mode. In response to receiving an interrupt, the platform firmware operating mode subroutine is executed in the isolated execution environment. In response to detecting an attempted access of a hardware resource resulting from execution of the platform firmware operating mode subroutine, the attempted access is blocked when the attempted access violates a security policy.

Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind ILT2, ILT4, or both ILT2 and ILT4, as well as compositions comprising the binding agents, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising the binding agents.

Abstract: Disclosed herein are biopolymer-based coatings and products incorporating such coatings. Related methods and use are also provided.

Abstract: Systems and devices for cooling and dispensing a beverage fluid are disclosed herein. One beverage dispensing system includes a beverage tower comprising a tower body, a shank, and a faucet. In some implementations, a coolant line is routed proximal to a beverage supply line through the tower body, through the shank, and into the faucet. In these and other implementations, the faucet includes a removable nozzle having a supplemental portion of the coolant line. In these and still other implementations, the faucet include a removable nozzle having a second coolant line. The coolant line and the second coolant line are configured to transport a coolant medium proximal to a beverage fluid in the beverage supply line to maintain or adjust the temperature of the beverage fluid. Many other features are described herein.

Abstract: In some embodiments, the present invention provides methods for making resorbable ear tubes including the steps of providing a silk fibroin solution, and forming a silk ear tube from the silk fibroin solution, wherein the silk ear tube is less than 2 mm in length and has an outer diameter of less than 1.5 mm, and wherein the silk ear tube is resorbable. In some embodiments, the present invention also provides methods for treating otitis media including the step of introducing a silk ear tube into the ear canal of a subject, wherein the silk ear tube is less than 2 mm in length and has an outer diameter of less than 1.5 mm, and wherein the silk ear tube is resorbed by the subject.

Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind ILT3, including human ILT3, as well as compositions comprising the binding agents, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising the binding agents.

Abstract: Systems and devices for cooling and dispensing a beverage fluid are disclosed herein. One beverage dispensing system includes a beverage tower comprising a tower body, a shank, and a faucet. In some implementations, a coolant line is routed proximal to a beverage supply line through the tower body, through the shank, and into the faucet. In these and other implementations, the faucet includes a removable nozzle having a supplemental portion of the coolant line. In these and still other implementations, the faucet include a removable nozzle having a second coolant line. The coolant line and the second coolant line are configured to transport a coolant medium proximal to a beverage fluid in the beverage supply line to maintain or adjust the temperature of the beverage fluid. Many other features are described herein.

Abstract: A virtualized computing environment is protected from a malicious hypervisor by restricting the hypervisor's access to one or more portions of an event (interrupt or exception) handling pathway of a guest virtual machine, wherein the guest virtual machine includes both a secure layer to manage security for the guest and one or more non-secure layers to handle event processing. The hypervisor is restricted from providing normal exception information to the guest virtual machine (referred to simply as a “guest” herein), and instead is only permitted to provide an event signal to the secure layer of the guest. In response to the event signal, the secure layer of the guest accesses a specified region of memory for the event information, reviews the information, and provides the information to another, non-secure, layer of the guest for processing only if the event information complies with specified security protocols.

Abstract: The present disclosure provides binding agents that modulate the interaction between LEAP2 and GHSR. Specifically, the present disclosure provides binding agents, such as LEAP2 peptides that bind GHSR and methods of their use to treat, ameliorate, or prevent a neuroendocrine and/or metabolic disease or disorder such as obesity, diabetes, acromegaly, gigantism and/or Prader-Willi syndrome. The present disclosure also provides binding agents, such as antibodies, that bind LEAP2, and methods of their use, to treat, ameliorate, or prevent a neuroendocrine and/or metabolic disease or disorder such as cachexia, anorexia, or other wasting syndromes.