Patents by Inventor David Kasler
David Kasler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250051709Abstract: An apparatus produces a target metabolite in a bioreaction. The apparatus has a reactor vessel that contains a bulk liquor in which the bioreaction is conducted, with a headspace provided above the bulk liquor. In some instances, the target metabolite is favorably partitioned into a foam formed at an interface of the bulk liquor and the headspace. A foam collector is arranged to receive this foam from the bioreactor and break it into a condensed foam liquid, from which the target metabolite may be isolated and purified. In one exemplary application, Paenibacillin is produced by fermentation of a medium by Paenibacillus polymyxa OSY-DF, and is preferentially concentrated in the foam. In another exemplary application, fermentation of a medium by Bacillus velezensis GF610 produces amyloliquecidin GF610 is which is preferentially concentrated in the foam.Type: ApplicationFiled: October 31, 2024Publication date: February 13, 2025Inventors: Ahmed Yousef, David Kasler, Emily Campbell
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Patent number: 12163116Abstract: An apparatus produces a target metabolite in a bioreaction. The apparatus has a reactor vessel that contains a bulk liquor in which the bioreaction is conducted, with a headspace provided above the bulk liquor. In some instances, the target metabolite is favorably partitioned into a foam formed at an interface of the bulk liquor and the headspace. A foam collector is arranged to receive this foam from the bioreactor and break it into a condensed foam liquid, from which the target metabolite may be isolated and purified. In one exemplary application, paenibacillin is produced by fermentation of a medium by Paenibacillus polymyxa OSY-DF, and is preferentially concentrated in the foam. In another exemplary application, fermentation of a medium by Bacillus velezensis GF610 produces amyloliquecidin GF610 is which is preferentially concentrated in the foam.Type: GrantFiled: August 21, 2020Date of Patent: December 10, 2024Assignee: Ohio State Innovation FoundationInventors: Ahmed Yousef, David Kasler, Emily Campbell
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Publication number: 20200377840Abstract: An apparatus produces a target metabolite in a bioreaction. The apparatus has a reactor vessel that contains a bulk liquor in which the bioreaction is conducted, with a headspace provided above the bulk liquor. In some instances, the target metabolite is favorably partitioned into a foam formed at an interface of the bulk liquor and the headspace. A foam collector is arranged to receive this foam from the bioreactor and break it into a condensed foam liquid, from which the target metabolite may be isolated and purified. In one exemplary application, paenibacillin is produced by fermentation of a medium by Paenibacillus polymyxa OSY-DF, and is preferentially concentrated in the foam. In another exemplary application, fermentation of a medium by Bacillus velezensis GF610 produces amyloliquecidin GF610 is which is preferentially concentrated in the foam.Type: ApplicationFiled: August 21, 2020Publication date: December 3, 2020Inventors: Ahmed YOUSEF, David KASLER, Emily CAMPBELL
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Patent number: 10466188Abstract: A thermal simulator simulates the thermal behavior of items such as eggs for which the actual internal temperature profile is difficult to measure. A yolk body simulates the egg yolk, an albumen body surrounds the yolk body and simulates the egg albumen, and a shell layer surrounds the albumen body to simulate the shell. The thermal properties of the materials forming the egg body, albumen body and shell layer are tuned to match the thermal properties of the egg yolk, egg albumen and egg shell. Thermometric devices are positioned within the egg body and egg albumen along with communication devices which process signals from the thermometric devices indicative of temperature and communicate these signals to a computer for further processing and display.Type: GrantFiled: January 6, 2017Date of Patent: November 5, 2019Assignee: OHIO STATE INNOVATION FOUNDATIONInventors: Ahmed Yousef, David Kasler, Mohammad Shavezipur
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Publication number: 20170115244Abstract: A thermal simulator simulates the thermal behavior of items such as eggs for which the actual internal temperature profile is difficult to measure. A yolk body simulates the egg yolk, an albumen body surrounds the yolk body and simulates the egg albumen, and a shell layer surrounds the albumen body to simulate the shell. The thermal properties of the materials forming the egg body, albumen body and shell layer are tuned to match the thermal properties of the egg yolk, egg albumen and egg shell. Thermometric devices are positioned within the egg body and egg albumen along with communication devices which process signals from the thermometric devices indicative of temperature and communicate these signals to a computer for further processing and display.Type: ApplicationFiled: January 6, 2017Publication date: April 27, 2017Applicant: OHIO STATE INNOVATION FOUNDATIONInventors: Ahmed Yousef, David Kasler, Mohammad Shavezipur
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Patent number: 9568457Abstract: A thermal simulator simulates the thermal behavior of items such as eggs for which the actual internal temperature profile is difficult to measure. A yolk body simulates the egg yolk, an albumen body surrounds the yolk body and simulates the egg albumen, and a shell layer surrounds the albumen body to simulate the shell. The thermal properties of the materials forming the egg body, albumen body and shell layer are tuned to match the thermal properties of the egg yolk, egg albumen and egg shell. Thermometric devices are positioned within the egg body and egg albumen along with communication devices which process signals from the thermometric devices indicative of temperature and communicate these signals to a computer for further processing and display.Type: GrantFiled: June 18, 2013Date of Patent: February 14, 2017Assignee: THE OHIO STATE UNIVERSITYInventors: Ahmed Yousef, David Kasler, Mohammad Shavezipur
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Patent number: 9113640Abstract: Coatings for shell eggs improve the strength and shatter resistance of processed eggs. The coatings include food grade natural resins such as shellac, mixtures of paraffin and beeswax, and food grade polymer emulsions such as polyvinyl acetate.Type: GrantFiled: September 12, 2013Date of Patent: August 25, 2015Assignee: Ohio State Innovation FoundationInventors: Ahmed E. Yousef, Tarik A. Yousef, David Kasler
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Publication number: 20150072050Abstract: Coatings for shell eggs improve the strength and shatter resistance of processed eggs. The coatings include food grade natural resins such as shellac, mixtures of paraffin and beeswax, and food grade polymer emulsions such as polyvinyl acetate.Type: ApplicationFiled: September 12, 2013Publication date: March 12, 2015Inventors: Ahmed E. Yousef, Tarik A. Yousef, David Kasler
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Publication number: 20140369383Abstract: A thermal simulator simulates the thermal behavior of items such as eggs for which the actual internal temperature profile is difficult to measure. A yolk body simulates the egg yolk, an albumen body surrounds the yolk body and simulates the egg albumen, and a shell layer surrounds the albumen body to simulate the shell. The thermal properties of the materials forming the egg body, albumen body and shell layer are tuned to match the thermal properties of the egg yolk, egg albumen and egg shell. Thermometric devices are positioned within the egg body and egg albumen along with communication devices which process signals from the thermometric devices indicative of temperature and communicate these signals to a computer for further processing and display.Type: ApplicationFiled: June 18, 2013Publication date: December 18, 2014Inventors: Ahmed Yousef, David Kasler, Mohammad Shavezipur
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Publication number: 20130251863Abstract: Apparatus for treating items with a treatment gas to decontaminate the items includes a chamber which receives the items. The chamber has a gas inlet in fluid communication with a distribution duct positioned within the chamber. The duct distributes the treatment gas throughout the chamber to prevent gas stratification. The chamber may also have a gas outlet for exhausting the chamber, a treatment gas source providing gas, such as ozone, carbon dioxide, or other treatment gas to the chamber. A vacuum pump is used to lower the pressure within the chamber and a purge pump is used to flush the treatment gas from the chamber upon completion of the treatment. A liquid reservoir is used to maintain a desired humidity within the chamber. A heat exchanger is used to maintain a desired temperature within the chamber, and a fan is used to circulate the treatment gas within the chamber.Type: ApplicationFiled: March 20, 2012Publication date: September 26, 2013Applicant: The Ohio State University Research FoundationInventors: Ahmed Yousef, Jennifer Perry, David Kasler, Sudhir Kartikeya Sastry