Abstract: There is described a method of preparing solid particles of a material, said method comprising controlling provision of a first liquid phase, wherein said first liquid phase comprises a solution of a first material through a membrane, said membrane defining a plurality of pores; and controlling provision of a second liquid phase, wherein said second liquid phase comprises a solution of a second material; reacting the first a second materials to produce a third liquid phase comprising a solution of a third material; and supersaturating the third liquid phase to form solid particles of the third material.

Abstract: The present invention generally relates to novel pharmaceutical formulations containing 2-[3,5-Bis(trifluoromethyl)phenyl]-N-{4-(4-fluoro-2-methylphenyl)-6-[(7S,9aS)-7-(hydroxymethyl) hexahydropyrazino [2,1-c] [1,4]oxazin-8(1H)-yl]-3-pyridinyl}-N,2-dimethylpropanamide, methods of preparation thereof and their use in medical therapy.

Abstract: Some implementations relate to methods, systems, and computer-readable media for providing audio for virtual experiences. In some implementations, a method includes receiving, at a server, a request to generate a plurality of sounds for a user device, wherein the request includes a prioritization value of at least one sound source of a plurality of sound sources, and wherein the user device is associated with a virtual experience hosted by the server, obtaining, by the server, sound source data for the plurality of sound sources, each sound source associated with a particular sound of the plurality of sounds, generating, by the server, an audio mix of the plurality of sounds based on the sound source data and the prioritization value of the at least one sound source of the plurality of sound sources, and transmitting the audio mix to the user device for playback at the user device.

Abstract: An aircraft system (10) for an aircraft (1) including a controller (100) configured to receive at least one signal during a take-off procedure of the aircraft. The signal includes information representative of at least one parameter of the aircraft. The controller is configured to determine whether a current or future aircraft climb rate associated with the take-off procedure meets a criterion, on the basis of the at least one signal. The controller is configured to determine at least one remedial action to be taken, such as performance of at least a portion of a procedure to retract a landing gear of the aircraft, when the controller determines that the aircraft climb rate does not meet the criterion.

Abstract: Apparatuses, systems, and techniques to perform computational operations in response to one or more compute uniform device architecture (CUDA) programs. In at least one embodiment, one or more computational operations are to cause one or more other computational operations to wait until a portion of matrix multiply-accumulate (MMA) operations have been performed.

Abstract: A method, apparatus, and computer readable medium for facilitating communication between a merchant and a client are provided. An example method may include creating a beautician identification record for a beautician, receiving an information related to an interaction between the beautician and a client, determining at least one product or service for the client from the information, and creating, using a processor, a communication to the client. The communication may include an indication of the at least one product or service. The method may also include sending the prescription to the client. Example systems, apparatuses, and computer readable media are also provided.

Abstract: The present invention relates to N-(2-aminophenyl)-4-(1-[(1,3-dimethyl-1H-pyrazol-4-yl)methyl]piperidin-4-yl)benzamide (CXD101), or a pharmaceutically acceptable salt thereof, for use as an anti-inflammatory agent, in particular for use in the treatment of immune checkpoint inhibitor-induced colitis.

Abstract: The invention provides an assay useful in predicting risk of 5-fluorouracil (FU) toxicity in a subject. The subject may be screened for the presence of at least one TYMS polymorphism and/or at least one DPYD polymorphism. Suitable TYMS and DPYD polymorphisms are provided. The presence of one or more of the polymorphisms indicates an increased risk of developing FU toxicity; a negative result may indicate a decreased risk of developing FU toxicity.

Abstract: A hub device that monitors characteristics of a transportation platform, such as a tractor trailer used for transporting goods, may establish connections with a plurality of external sensors. In order to simplify the pairing process between the hub devices and the external sensors, the hub device may be receiving IDs of the sensors to pair to from a remote server. A technician may physically scan tags, for example a barcode or an NFC tag, of the sensors and hub device, which are then transmitted to the remote server in order to identify which hub and sensors should be paired.

Abstract: Quantitative analysis of a tissue sample includes carrying out a ploidy measurement on a plurality of nuclei of the sample to determine the ploidy type of a sample and also carrying out a stroma measurement on a section to determine the stroma type of a sample. The ploidy type, e.g. diploid or non-diploid, and the stroma type, high or low stroma, give an improved patient survival estimate than the ploidy type alone.

Abstract: The invention provides an assay useful in predicting risk of 5-fluorouracil (FU) toxicity in a subject. The subject may be screened for the presence of at least one TYMS polymorphism and/or at least one DPYD polymorphism. Suitable TYMS and DPYD polymorphisms are provided. The presence of one or more of the polymorphisms indicates an increased risk of developing FU toxicity; a negative result may indicate a decreased risk of developing FU toxicity.

Abstract: A new pump design is described. The pump features a casing with a continuous enclosure extending from a power end of the casing to a fluid end of the casing for housing the reciprocating assembly of the pump, which includes a crankshaft, a plurality of control rods coupled to the crankshaft, and a plurality of crossheads coupled to the control rods. A detachable lid is attached to the casing at the power end and the fluid end of the casing, and encloses the reciprocating assembly. An alignment plate oriented substantially parallel to a stroke axis of the pump maintains alignment of the crossheads.

Abstract: A new pump design is described. The pump features a casing with a continuous enclosure extending from a power end of the casing to a fluid end of the casing for housing the reciprocating assembly of the pump, which includes a crankshaft, a plurality of control rods coupled to the crankshaft, and a plurality of crossheads coupled to the control rods. A detachable lid is attached to the casing at the power end and the fluid end of the casing, and encloses the reciprocating assembly. An alignment plate oriented substantially parallel to a stroke axis of the pump maintains alignment of the crossheads.

Abstract: In one aspect, the invention relates to a method of performing upsampling, that includes the steps of: receiving an input image; generating an initial upsampled image using the input image; generating a low-passed image using the input image; and performing self-similarity upsampling using the upsampled image and the low-passed image.

Abstract: Disclosed is a method of performing upscaling that includes the steps of: parsing an input video; breaking the input video into individual frames; performing upscaling on the individual frames to produce upscaled frames; and stitching the upscaled frames together to produce an upscaled video.

Abstract: Quantitative analysis of a tissue sample includes carrying out a ploidy measurement on a plurality of nuclei of the sample to determine the ploidy type of a sample and also carrying out a stroma measurement on a section to determine the stroma type of a sample. The ploidy type, e.g. diploid or non-diploid, and the stroma type, high or low stroma, give an improved patient survival estimate than the ploidy type alone.

Abstract: A new pump design is described. The pump features a casing with a continuous enclosure extending from a power end of the casing to a fluid end of the casing for housing the reciprocating assembly of the pump, which includes a crankshaft, a plurality of control rods coupled to the crankshaft, and a plurality of crossheads coupled to the control rods. A detachable lid is attached to the casing at the power end and the fluid end of the casing, and encloses the reciprocating assembly. An alignment plate oriented substantially parallel to a stroke axis of the pump maintains alignment of the crossheads.

Abstract: A new pump design is described. The pump features a casing with a continuous enclosure extending from a power end of the casing to a fluid end of the casing for housing the reciprocating assembly of the pump, which includes a crankshaft, a plurality of control rods coupled to the crankshaft, and a plurality of crossheads coupled to the control rods. A detachable lid is attached to the casing at the power end and the fluid end of the casing, and encloses the reciprocating assembly. An alignment plate oriented substantially parallel to a stroke axis of the pump maintains alignment of the crossheads.