Abstract: An electrically conductive component is provided for a near-wafer environment of an ion implantation system, where the component has a carbon-based substrate having a microscopically textured surface overlying a macroscopically textured surface. The macroscopically textured surface is a mechanically, chemically, or otherwise roughened surface. The microscopically textured surface can be a converted surface formed by a chemical reaction forming a non-stoichiometric silicon and carbon surface. The one or more components can be a dose cup, exit aperture, and tunnel wall. The carbon-based substrate can be graphite. The microscopically textured surface can be a modified graphite surface. No defined interface layer exists between the microscopically textured surface and macroscopically textured surface. The carbon-based graphite is selected based on a final porosity and grain size of the graphite.

Abstract: An electrically conductive component is provided for a near-wafer environment of an ion implantation system, where the component has a carbon-based substrate having a microscopically textured surface overlying a macroscopically textured surface. The macroscopically textured surface is a mechanically, chemically, or otherwise roughened surface. The microscopically textured surface can be a converted surface formed by a chemical reaction forming a non-stoichiometric silicon and carbon surface. The one or more components can be a dose cup, exit aperture, and tunnel wall. The carbon-based substrate can be graphite. The microscopically textured surface can be a modified graphite surface. No defined interface layer exists between the microscopically textured surface and macroscopically textured surface. The carbon-based graphite is selected based on a final porosity and grain size of the graphite.

Abstract: The present invention broadly relates to the synergistic attenuation of vesicular stomatitis virus (VSV), More particularly, the invention relates to the identification of combined mutation classes which synergistically attenuate the pathogenicity of VSV vectors in mammals and immunogenic compositions thereof.

Abstract: The present invention broadly relates to the synergistic attenuation of vesicular stomatitis virus (VSV), More particularly, the invention relates to the identification of combined mutation classes which synergistically attenuate the pathogenicity of VSV vectors in mammals and immunogenic compositions thereof.

Abstract: The present invention relates to genetically engineered recombinant respiratory syncytial viruses and viral vectors which contain deletions of various viral accessory gene(s) either singly or in combination. In accordance with the present invention, the recombinant respiratory syncytial viral vectors and viruses are engineered to contain complete deletions of the M2-2, NS1, NS2, or SH viral accessory genes or various combinations thereof. In addition, the present invention relates to the attenuation of respiratory syncytial virus by mutagenisis of the M2-1 gene.

Abstract: The present invention broadly relates to the synergistic attenuation of vesicular stomatitis virus (VSV). More particularly, the invention relates to the identification of combined mutation classes which synergistically attenuate the pathogenicity of VSV vectors in mammals and immunogenic compositions thereof.

Abstract: The present invention relates to ion sources (14) comprising a cathode (20) and a counter-cathode (44) that are suitable for ion implanters (10). Typically, the ion source is held under vacuum and produces ions using a plasma generated within an arc chamber (16). Plasma ions are extracted from the arc chamber and subsequently implanted in a semiconductor wafer (12). The ion source according to the present invention further comprises a cathode (40) arranged to emit electrons into the arc chamber; an electrode (44) positioned in the arc chamber such that electrons emitted by the cathode are incident thereon; one or more voltage potential sources (76) arranged to bias the electrode; and a voltage potential adjuster (82) operable to switch between the voltage potential source biasing the electrode positively thereby to act as an anode and the voltage potential source biasing the electrode negatively thereby to act as a counter-cathode.

Abstract: The present invention relates to genetically engineered recombinant respiratory syncytial viruses and viral vectors which contain deletions of various viral accessory gene(s) either singly or in combination. In accordance with the present invention, the recombinant respiratory syncytial viral vectors and viruses are engineered to contain complete deletions of the M2-2, NS1, NS2, or SH viral accessory genes or various combinations thereof. In addition, the present invention relates to the attenuation of respiratory syncytial virus by mutagenisis of the M2-1 gene.

Abstract: This invention is directed to a pole for supporting an intravenous bag for use in the field on uneven or soft terrain. The pole has a pointed tip which may be pressed into soft ground, mud, tundra or ice. The pole is inexpensive to make, collapsible for storage and may be easily transported.

Abstract: The present invention relates to genetically engineered recombinant respiratory syncytial viruses and viral vectors which contain deletions of various viral accessory gene(s) either singly or in combination. In accordance with the present invention, the recombinant respiratory syncytial viral vectors and viruses are engineered to contain complete deletions of the M2-2, NS1, NS2, or SH viral accessory genes or various combinations thereof. In addition, the present invention relates to the attenuation of respiratory syncytial virus by mutagenisis of the M2-1 gene.

Abstract: The present invention relates to ion sources (14) comprising a cathode (20) and a counter-cathode (44) that are suitable for ion implanters (10). Typically, the ion source is held under vacuum and produces ions using a plasma generated within an arc chamber (16). Plasma ions are extracted from the arc chamber and subsequently implanted in a semiconductor wafer (12). The ion source according to the present invention further comprises a cathode (40) arranged to emit electrons into the arc chamber; an electrode (44) positioned in the arc chamber such that electrons emitted by the cathode are incident thereon; one or more voltage potential sources (76) arranged to bias the electrode; and a voltage potential adjuster (82) operable to switch between the voltage potential source biasing the electrode positively thereby to act as an anode and the voltage potential source biasing the electrode negatively thereby to act as a counter-cathode.

Abstract: Modular system for platform and shelving structures. In an assembled configuration, a module has a central vertical member hingedly-coupled to a second vertical member extending perpendicular to a first side of the central member, and a horizontal member hingedly-coupled to the central member and extending perpendicular to a second side of the central vertical member. The upper edges of the central vertical member and the second vertical member of a first module provide support to a horizontal member of a second module, whereby various structures can be formed from a plurality of modules. Each module is stowable by rotating the second vertical member and the horizontal member about their hinged edges toward the central vertical member. One or more of the members can include key portions adapted to interlock with a member of an adjacent module when in an assembled configuration.

Abstract: Modular system for constructing platform and shelving structures. Each module is configurable in either a stowable or assembled configuration. In the assembled configuration, a module has a central vertical member hingedly-coupled to a second vertical member extending perpendicular to a first side of the central member, and a horizontal member hingedly-coupled to the central member and extending perpendicular to a second side of the central vertical member. The upper edges of the central vertical member and the second vertical member of a first module provide support to a horizontal member of a second module, whereby various structures can be formed from a plurality of modules. Each module is easily stowable by rotating the second vertical member and the horizontal member about their hinged edges toward the central vertical member until they are substantially parallel and adjacent thereto, whereby a plurality of modules in the stowable configuration can be stored in substantially the minimum possible space.

Abstract: The present invention is directed to a method for generating an antigen-specific immune response in a subject in general and in particular to administering a priming dose of an immunogenic composition of a recombinant mumps virus (rMuV) that encodes an antigen followed by administering a boosting dose of recombinant vesicular stomatitis virus (rVSV) encoding an antigen.

Abstract: Modular system for platform and shelving structures. In an assembled configuration, a module has a central vertical member hingedly-coupled to a second vertical member extending perpendicular to a first side of the central member, and a horizontal member hingedly-coupled to the central member and extending perpendicular to a second side of the central vertical member. The upper edges of the central vertical member and the second vertical member of a first module provide support to a horizontal member of a second module, whereby various structures can be formed from a plurality of modules. Each module is stowable by rotating the second vertical member and the horizontal member about their hinged edges toward the central vertical member. One or more of the members can include key portions adapted to interlock with a member of an adjacent module when in an assembled configuration.

Abstract: Modular system for constructing platform and shelving structures. Each module is configurable in either a stowable or assembled configuration. In the assembled configuration, a module has a central vertical member hingedly-coupled to a second vertical member extending perpendicular to a first side of the central member, and a horizontal member hingedly-coupled to the central member and extending perpendicular to a second side of the central vertical member. The upper edges of the central vertical member and the second vertical member of a first module provide support to a horizontal member of a second module, whereby various structures can be formed from a plurality of modules. Each module is easily stowable by rotating the second vertical member and the horizontal member about their hinged edges toward the central vertical member until they are substantially parallel and adjacent thereto, whereby a plurality of modules in the stowable configuration can be stored in substantially the minimum possible space.

Abstract: The present invention relates to genetically engineered recombinant RS viruses and viral vectors which contain heterologous genes which for the use as vaccines. In accordance with the present invention, the recombinant RS viral vectors and viruses are engineered to contain heterologous genes, including genes of other viruses, pathogens, cellular genes, tumor antigens, or to encode combinations of genes from different strains of RSV.

Abstract: An improved web page in which a hyperlink object on the web page is linked to a search engine which will search all or any specified web pages to identify those in which that object occurs, or which contains subject matter relevant to that object and these can then be displayed to a user. This allows the user to identify a plurality of relevant web pages which might be of interest rather than being directed only to one specific page, as with a conventional hyperlink.

Abstract: Recombinant negative strand virus RNA templates which may be used to express heterologous gene products and/or to construct chimeric viruses are described. Influenza viral polymerase, which was prepared depleted of viral RNA, was used to copy small RNA templates prepared from plasmid-encoded sequences. Template constructions containing only the 3' end of genomic RNA were shown to be efficiently copied, indicative that the promoter lay solely within the 15 nucleotide 3' terminus. Sequences not specific for the influenza viral termini were not copied, and, surprisingly, RNAs containing termini identical to those from plus sense cRNA were copied at low levels. The specificity for recognition of the virus-sense promoter was further defined by site-specific mutagenesis. It was also found that increased level of viral protein were required in order to catalyze both the cap-endonuclease primed and primer-free RNA synthesis from these model templates as well as from genomic length RNAs.