Abstract: This application describes systems and methods for generating machine learning models (MLMs). An exemplary method includes obtaining a sample and user input data characterizing a product or service. A subset of the data is selected from the sample based on sampling the sample according to the user input data. An MLM is trained by applying the data subset as training input to the MLM, thereby providing a trained MLM to emulate a customer selection process unique to the product or service. A user interface (UI) configured to receive other user input data and cause the trained MLM to execute on the other user input data, thereby testing the trained MLM, is presented. A summary of results from the execution of the trained MLM is generated and presented in the UI. The summary of results indicates a contribution to the trained MLM of each of a plurality of features.

Abstract: In some implementations, an optical device includes a one-way mirror formed by a polarization selective mirror and an absorptive polarizer. The absorptive polarizer has a transmission axis aligned with the transmission axis of the reflective polarizer. The one-way mirror may be provided on the world side of a head-mounted display system. Advantageously, the one-way mirror may reflect light from the world, which provides privacy and may improve the cosmetics of the display. In some implementations, the one-way mirror may include one or more of a depolarizer and a pair of opposing waveplates to improve alignment tolerances and reduce reflections to a viewer. In some implementations, the one-way mirror may form a compact integrated structure with a dimmer for reducing light transmitted to the viewer from the world.

Abstract: In some implementations, an optical device includes a one-way mirror formed by a polarization selective mirror and an absorptive polarizer. The absorptive polarizer has a transmission axis aligned with the transmission axis of the reflective polarizer. The one-way mirror may be provided on the world side of a head-mounted display system. Advantageously, the one-way mirror may reflect light from the world, which provides privacy and may improve the cosmetics of the display. In some implementations, the one-way mirror may include one or more of a depolarizer and a pair of opposing waveplates to improve alignment tolerances and reduce reflections to a viewer. In some implementations, the one-way mirror may form a compact integrated structure with a dimmer for reducing light transmitted to the viewer from the world.

Abstract: An eyepiece and waveguide for viewing a projected image in a virtual reality and augmented reality imaging and visualization system. The waveguide may include a substrate for guiding light. The waveguide may also include an incoupling diffractive element disposed within or on the substrate and configured to diffract an incoupled light related to the projected image into the substrate. The waveguide may further include a first grating disposed within or on the substrate and configured to manipulate the diffracted incoupled light from the incoupling diffractive element so as to multiply the projected image and to direct the multiplied projected image to a second grating. The second grating may be disposed within or on the substrate and may be configured to outcouple the manipulated diffracted incoupled light from the waveguide. The first grating and the second grating may occupy a same region of the waveguide.

Abstract: Diseases associated with the tissues in the posterior segment of the eye can be effectively treated by administering therapeutic agents transsclerally to those tissues. Compositions, devices, and methods for delivering therapeutic agents so that they cross the sclera and reach these tissues include injecting solutions or suspensions adjacent to or within the sclera and implanting solid structures containing the therapeutic agent adjacent to or within the sclera. These methods may be used for administering rapamycin or related compounds to treat choroidal neovascularization associated with age-related macular degeneration.

Abstract: Described herein are formulations and methods for treating, inhibiting, preventing, delaying onset, or causing regression of a disease or condition relating to vascular permeability.

Abstract: An integrated cooker-strainer system for food preparation. The device includes a pot assembly operatively associated with a strainer assembly. The integrated system has a first position wherein a handle and container of the strainer assembly is substantially engaged in a handle and container of the pot assembly. In both the first and second position, a sealed mating portion between the strainer and pot maintains contact between the surfaces, preventing the leakage of liquid at this point. The integrated system may be used for a variety of other purposes, for example, as a meat strainer, colander, steamer, and produce shaker. The integrated system may be used for baking, microwave or stovetop cooking. A hand-operated pressing mechanism can be employed to accelerate drainage of liquid from food.

Abstract: Diseases associated with the tissues in the posterior segment of the eye can be effectively treated by administering therapeutic agents transsclerally to those tissues. Compositions, devices, and methods for delivering therapeutic agents so that they cross the sclera and reach these tissues include injecting solutions or suspensions adjacent to or within the sclera and implanting solid structures containing the therapeutic agent adjacent to or within the sclera. These methods may be used for administering rapamycin or related compounds to treat choroidal neovascularization associated with age-related macular degeneration.

Abstract: A network-based diagnosis server for monitoring and diagnosing a system, the server being remote from the system it is observing, comprises a sensor for generating signals indicative of a characteristic of a component of the system, a network-interfaced sensor agent coupled to the sensor for receiving signals therefrom, a broker module coupled to the network for sending signals to and receiving signals from the sensor agent, a handler application connected to the broker module for transmitting signals to and receiving signals therefrom, a reasoner application in communication with the handler application for processing, and responding to signals received from the handler application, wherein the sensor agent, broker module, handler application, and reasoner applications operate simultaneously relative to each other, such that the present invention diagnosis server performs continuous monitoring and diagnosing of said components of the system in real time.