Abstract: A beverage preparation capsule containing a beverage preparation ingredient, having a body with side walls formed from one or more substantially air- and liquid-impermeable sheet materials defining a chamber containing a beverage preparation ingredient and further defining an outlet channel having an upstream end in fluid communication with the chamber for escape of beverage from the chamber. At least a region of the outlet channel is filled by a filtration material for filtering the beverage escaping from the chamber. Also provided is a clamp assembly for preparing a beverage from such a capsule, the clamp assembly comprising two or more clamp members, wherein an inner wall of at least one of the clamp members comprises a concave base surface for receiving the capsule and one or more pressure pads projecting from the concave base surface for selectively constricting a region of the capsule.

Abstract: A beverage preparation capsule containing a beverage preparation ingredient, having a body with side walls formed from one or more substantially air- and liquid-impermeable sheet materials defining a chamber containing a beverage preparation ingredient and further defining an outlet channel having an upstream end in fluid communication with the chamber for escape of beverage from the chamber. At least a region of the outlet channel is filled by a filtration material for filtering the beverage escaping from the chamber. Also provided is a clamp assembly for preparing a beverage from such a capsule, the clamp assembly comprising two or more clamp members, wherein an inner wall of at least one of the clamp members comprises a concave base surface for receiving the capsule and one or more pressure pads projecting from the concave base surface for selectively constricting a region of the capsule.

Abstract: A method for making and/or dispensing a beverage may be provided. For example, a beverage may be selected from a user interface of a beverage dispensing apparatus. A beverage pressure value may be provided. A package containing a beverage preparation ingredient may be inserted into the beverage dispensing apparatus. A type of the inserted package may be detected. A package pressure value for the inserted package may be determined based on the type of the inserted package. If the package pressure value corresponds to the beverage pressure value, the beverage dispensing apparatus may inject a liquid into the inserted package at the beverage pressure value. If the package pressure value does not correspond to the beverage pressure value, the beverage dispensing apparatus may inject the liquid into the inserted package at the package pressure value. The selected beverage and/or the modified beverage may be dispensed into a drinking vessel.

Abstract: A method, apparatus, and/or system may be provided for dispensing a beverage. In an example, a beverage preparation machine may include a container compartment for receiving a beverage packet comprising beverage ingredients. An outlet may be configured to dispense a beverage flavored by the beverage packet. A communication interface may be configured to receive a wireless signal from an electronic device, the wireless signal comprising an identifier of the electronic device. A processor may be operably coupled to the communication interface. The processor may be configured to receive the identifier of the electronic device; associate the identifier of the electronic device with a user and a beverage preference of the user; and cause the beverage dispensed by the outlet to be based on the beverage preference of the user.

Abstract: The subject disclosure presents systems and computer-implemented methods for assessing a risk of cancer recurrence in a patient based on a holistic integration of large amounts of prognostic information for said patient into a single comparative prognostic dataset. A risk classification system may be trained using the large amounts of information from a cohort of training slides from several patients, along with survival data for said patients. For example, a machine-learning-based binary classifier in the risk classification system may be trained using a set of granular image features computed from a plurality of slides corresponding to several cancer patients whose survival information is known and input into the system. The trained classifier may be used to classify image features from one or more test patients into a low-risk or high-risk group.

Abstract: The subject disclosure presents systems and computer-implemented methods for assessing a risk of cancer recurrence in a patient based on a holistic integration of large amounts of prognostic information for said patient into a single comparative prognostic dataset. A risk classification system may be trained using the large amounts of information from a cohort of training slides from several patients, along with survival data for said patients. For example, a machine-learning-based binary classifier in the risk classification system may be trained using a set of granular image features computed from a plurality of slides corresponding to several cancer patients whose survival information is known and input into the system. The trained classifier may be used to classify image features from one or more test patients into a low-risk or high-risk group.

Abstract: A beverage-ingredient container to be used in the preparation of a beverage by a beverage dispensing apparatus. The container has a first optical code on the first surface of the container, wherein the first optical code is positioned on a first surface to be read by an optical scanner of the beverage dispensing apparatus when the container is received by the apparatus in a first orientation, and a second optical code on a second surface of the container, wherein the second optical code is positioned on the second surface to be read by the optical scanner of the beverage dispensing apparatus when the container is in a second orientation. The first optical code and the second optical code each stores container-related information including a container identifier which, when read by the optical scanner of the beverage dispensing apparatus, can be used by the beverage dispensing apparatus to control beverage preparation.

Abstract: Compounds comprising phosphorescent metal complexes comprising cyclometallated ligands having a structure of In the vgs3, each of the E1 atoms is selected from C and N, except that E1g is selected from C, N, and S. The E1 atoms collectively comprise an 18 pi-electron system, provided that E1a and E1p are different. The R1 substituents are each, independently, H, hydrocarbyl, heteroatom substituted hydrocarbyl, cyano, fluoro, OR2a, SR2a, NR2aR2b, BR2aR2b, or SiR2aR2bR2c, where the R2 substituents are each, independently, hydrocarbyl or heteroatom substituted hydrocarbyl. Any of the R1 or R2 substituents can be linked to form a saturated or unsaturated, aromatic or non-aromatic ring, provided that the R1 substituents are not present when the corresponding one of E atoms is N or S. Organic light emitting diode devices comprising these compounds are also described.

Abstract: A beverage preparation capsule including front and back sheets that are bonded together along a top edge, first and second side edges, and a bottom edge. A region of bonding along the bottom edge may be releasable to allow escape of beverage from the capsule during beverage preparation. There may be a transverse seal that is interrupted by a gap that provides fluid communication between a beverage ingredient chamber located above said gap and a beverage outlet chamber located below said gap. A folded filter strip extending across the capsule includes a fold extending transversely below said transverse seal and front and back side panels extending upwardly through said transverse seal that are bonded to the front and back sheets of the capsule, respectively. The front and back side panels may not extend more than about 10 mm into said beverage ingredient chamber above said transverse seal.

Abstract: A beverage preparation apparatus for preparation of a beverage from a capsule in a clamp assembly (30). The clamp assembly has a first clamp member (31) and a second clamp member, where the inner surfaces of the first clamp member and the second clamp member form a clamp chamber (33) for substantially enclosing and supporting a capsule (10) during beverage preparation. The second clamp member comprises a rigid peripheral frame (32) having a central void and a resilient layer (37) extending across said central void. There is a piston (36) positioned in the central void and resiliently coupled to the peripheral frame (32) to allow limited resilient movement of the rigid peripheral frame (32) relative to the piston (36).

Abstract: Compounds comprising phosphorescent metal complexes comprising cyclometallated ligands having a structure of In the vgs3, each of the E1 atoms is selected from C and N, except that E1g is selected from C, N, and S. The E1 atoms collectively comprise an 18 pi-electron system, provided that E1a and E1p are different. The R1 substituents are each, independently, H, hydrocarbyl, heteroatom substituted hydrocarbyl, cyano, fluoro, OR2a, SR2a, NR2aR2b, BR2aR2b, or SiR2aR2bR2c, where the R2 substituents are each, independently, hydrocarbyl or heteroatom substituted hydrocarbyl. Any of the R1 or R2 substituents can be linked to form a saturated or unsaturated, aromatic or non-aromatic ring, provided that the R1 substituents are not present when the corresponding one of E atoms is N or S. Organic light emitting diode devices comprising these compounds are also described.

Abstract: Compounds comprising phosphorescent metal complexes comprising cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1?,2?-c]quinazoline ligands, or isoelectronic or benzannulated analogs thereof, are described. Organic light emitting diode devices comprising these compounds are also described.

Abstract: A beverage preparation capsule containing a beverage preparation ingredient, having a body with side walls formed from one or more substantially air- and liquid-impermeable sheet materials defining a chamber containing a beverage preparation ingredient and further defining an outlet channel having an upstream end in fluid communication with the chamber for escape of beverage from the chamber. At least a region of the outlet channel is filled by a filtration material for filtering the beverage escaping from the chamber. Also provided is a clamp assembly for preparing a beverage from such a capsule, the clamp assembly comprising two or more clamp members, wherein an inner wall of at least one of the clamp members comprises a concave base surface for receiving the capsule and one or more pressure pads projecting from the concave base surface for selectively constricting a region of the capsule.

Abstract: The subject disclosure presents systems and computer-implemented methods for assessing a risk of cancer recurrence in a patient based on a holistic integration of large amounts of prognostic information for said patient into a single comparative prognostic dataset. A risk classification system may be trained using the large amounts of information from a cohort of training slides from several patients, along with survival data for said patients. For example, a machine-learning-based binary classifier in the risk classification system may be trained using a set of granular image features computed from a plurality of slides corresponding to several cancer patients whose survival information is known and input into the system. The trained classifier may be used to classify image features from one or more test patients into a low-risk or high-risk group.

Abstract: A beverage preparation capsule containing a beverage preparation ingredient, having a body with side walls formed from one or more substantially air- and liquid-impermeable sheet materials defining a chamber containing a beverage preparation ingredient and further defining an outlet channel having an upstream end in fluid communication with the chamber for escape of beverage from the chamber. At least a region of the outlet channel is filled by a filtration material for filtering the beverage escaping from the chamber. Also provided is a clamp assembly for preparing a beverage from such a capsule, the clamp assembly comprising two or more clamp members, wherein an inner wall of at least one of the clamp members comprises a concave base surface for receiving the capsule and one or more pressure pads projecting from the concave base surface for selectively constricting a region of the capsule.

Abstract: The subject disclosure presents systems and computer-implemented methods for assessing a risk of cancer recurrence in a patient based on a holistic integration of large amounts of prognostic information for said patient into a single comparative prognostic dataset. A risk classification system may be trained using the large amounts of information from a cohort of training slides from several patients, along with survival data for said patients. For example, a machine-learning-based binary classifier in the risk classification system may be trained using a set of granular image features computed from a plurality of slides corresponding to several cancer patients whose survival information is known and input into the system. The trained classifier may be used to classify image features from one or more test patients into a low-risk or high-risk group.

Abstract: Compounds comprising phosphorescent metal complexes comprising cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1?,2?-c]quinazoline ligands, or isoelectronic or benzannulated analogs thereof, are described. Organic light emitting diode devices comprising these compounds are also described.

Abstract: Compounds comprising phosphorescent metal complexes comprising cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1?,2?-c]quinazoline ligands, or isoelectronic or benzannulated analogs thereof, are described. Organic light emitting diode devices comprising these compounds are also described.

Abstract: Compounds comprising phosphorescent metal complexes comprising cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1?,2?-c]quinazoline ligands, or isoelectronic or benzannulated analogs thereof, are described. Organic light emitting diode devices comprising these compounds are also described.

Abstract: Compounds comprising phosphorescent metal complexes comprising cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1?,2?-c]quinazoline ligands, or isoelectronic or benzannulated analogs thereof, are described. Organic light emitting diode devices comprising these compounds are also described.