Patents by Inventor David Knowles
David Knowles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12258205Abstract: A beverage preparation capsule containing a beverage preparation ingredient, having a body with side walls formed from one or more substantially air- and liquid-impermeable sheet materials defining a chamber containing a beverage preparation ingredient and further defining an outlet channel having an upstream end in fluid communication with the chamber for escape of beverage from the chamber. At least a region of the outlet channel is filled by a filtration material for filtering the beverage escaping from the chamber. Also provided is a clamp assembly for preparing a beverage from such a capsule, the clamp assembly comprising two or more clamp members, wherein an inner wall of at least one of the clamp members comprises a concave base surface for receiving the capsule and one or more pressure pads projecting from the concave base surface for selectively constricting a region of the capsule.Type: GrantFiled: June 5, 2023Date of Patent: March 25, 2025Assignee: Luigi Lavazza S.p.A.Inventors: Peter Austin, Paul Fletcher, David Knowles, Sam Hyde
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Patent number: 12157625Abstract: A beverage-ingredient container to be used in the preparation of a beverage by a beverage dispensing apparatus. The container has a first optical code on the first surface of the container, wherein the first optical code is positioned on a first surface to be read by an optical scanner of the beverage dispensing apparatus when the container is received by the apparatus in a first orientation, and a second optical code on a second surface of the container, wherein the second optical code is positioned on the second surface to be read by the optical scanner of the beverage dispensing apparatus when the container is in a second orientation. The first optical code and the second optical code each stores container-related information including a container identifier which, when read by the optical scanner of the beverage dispensing apparatus, can be used by the beverage dispensing apparatus to control beverage preparation.Type: GrantFiled: August 16, 2019Date of Patent: December 3, 2024Assignee: Luigi Lavazza S.p.A.Inventors: David Knowles, Stephen Hobden, David Hay, Maciej Dykier
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Publication number: 20240385027Abstract: A system and a method include a container configured to retain one or more liquids. A liquid level sensor is disposed within the container. The liquid level sensor includes a plurality of sensing elements configured to sense a level of the one or more liquids within the container. In at least one example, the sensing elements are optical fibers.Type: ApplicationFiled: October 3, 2023Publication date: November 21, 2024Applicants: THE BOEING COMPANY, ADVANCED FIBREOPTICS ENGINEERING LTDInventors: John Alfred Weidler, Elaine Cheng Wright, Timothy James Wheeler, John Everett Groat, Christopher John Lewins, Mark Robert Johnson, Patrick David Knowles, Marco Zanola
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Patent number: 12100146Abstract: The subject disclosure presents systems and computer-implemented methods for assessing a risk of cancer recurrence in a patient based on a holistic integration of large amounts of prognostic information for said patient into a single comparative prognostic dataset. A risk classification system may be trained using the large amounts of information from a cohort of training slides from several patients, along with survival data for said patients. For example, a machine-learning-based binary classifier in the risk classification system may be trained using a set of granular image features computed from a plurality of slides corresponding to several cancer patients whose survival information is known and input into the system. The trained classifier may be used to classify image features from one or more test patients into a low-risk or high-risk group.Type: GrantFiled: March 2, 2022Date of Patent: September 24, 2024Assignees: Ventana Medical Systems, Inc., The Board of Trustees of the Leland Stanford Junior UniversityInventors: Michael Barnes, Srinivas Chukka, David Knowles
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Patent number: 11667464Abstract: A beverage preparation capsule containing a beverage preparation ingredient, having a body with side walls formed from one or more substantially air- and liquid-impermeable sheet materials defining a chamber containing a beverage preparation ingredient and further defining an outlet channel having an upstream end in fluid communication with the chamber for escape of beverage from the chamber. At least a region of the outlet channel is filled by a filtration material for filtering the beverage escaping from the chamber. Also provided is a clamp assembly for preparing a beverage from such a capsule, the clamp assembly comprising two or more clamp members, wherein an inner wall of at least one of the clamp members comprises a concave base surface for receiving the capsule and one or more pressure pads projecting from the concave base surface for selectively constricting a region of the capsule.Type: GrantFiled: January 3, 2020Date of Patent: June 6, 2023Assignee: LAVAZZA PROFESSIONAL NORTH AMERICA, LLCInventors: Peter Austin, Paul Fletcher, David Knowles, Sam Hyde
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Publication number: 20220189016Abstract: The subject disclosure presents systems and computer-implemented methods for assessing a risk of cancer recurrence in a patient based on a holistic integration of large amounts of prognostic information for said patient into a single comparative prognostic dataset. A risk classification system may be trained using the large amounts of information from a cohort of training slides from several patients, along with survival data for said patients. For example, a machine-learning-based binary classifier in the risk classification system may be trained using a set of granular image features computed from a plurality of slides corresponding to several cancer patients whose survival information is known and input into the system. The trained classifier may be used to classify image features from one or more test patients into a low-risk or high-risk group.Type: ApplicationFiled: March 2, 2022Publication date: June 16, 2022Inventors: Michael Barnes, Srinivas Chukka, David Knowles
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Patent number: 11288795Abstract: The subject disclosure presents systems and computer-implemented methods for assessing a risk of cancer recurrence in a patient based on a holistic integration of large amounts of prognostic information for said patient into a single comparative prognostic dataset. A risk classification system may be trained using the large amounts of information from a cohort of training slides from several patients, along with survival data for said patients. For example, a machine-learning-based binary classifier in the risk classification system may be trained using a set of granular image features computed from a plurality of slides corresponding to several cancer patients whose survival information is known and input into the system. The trained classifier may be used to classify image features from one or more test patients into a low-risk or high-risk group.Type: GrantFiled: October 21, 2019Date of Patent: March 29, 2022Assignee: Ventana Medical Systems, Inc.Inventors: Michael Barnes, Srinivas Chukka, David Knowles
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Patent number: 10978649Abstract: Compounds comprising phosphorescent metal complexes comprising cyclometallated ligands having a structure of In the vgs3, each of the E1 atoms is selected from C and N, except that E1g is selected from C, N, and S. The E1 atoms collectively comprise an 18 pi-electron system, provided that E1a and E1p are different. The R1 substituents are each, independently, H, hydrocarbyl, heteroatom substituted hydrocarbyl, cyano, fluoro, OR2a, SR2a, NR2aR2b, BR2aR2b, or SiR2aR2bR2c, where the R2 substituents are each, independently, hydrocarbyl or heteroatom substituted hydrocarbyl. Any of the R1 or R2 substituents can be linked to form a saturated or unsaturated, aromatic or non-aromatic ring, provided that the R1 substituents are not present when the corresponding one of E atoms is N or S. Organic light emitting diode devices comprising these compounds are also described.Type: GrantFiled: July 13, 2020Date of Patent: April 13, 2021Assignee: UNIVERSAL DISPLAY CORPORATIONInventors: David Knowles, Chun Lin, Peter Mackenzie, Jui-Yi Tsai, Robert W. Walters, Scott Beers, Cory S. Brown, Walter Yeager
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Patent number: 10863856Abstract: A beverage preparation apparatus for preparation of a beverage from a capsule in a clamp assembly (30). The clamp assembly has a first clamp member (31) and a second clamp member, where the inner surfaces of the first clamp member and the second clamp member form a clamp chamber (33) for substantially enclosing and supporting a capsule (10) during beverage preparation. The second clamp member comprises a rigid peripheral frame (32) having a central void and a resilient layer (37) extending across said central void. There is a piston (36) positioned in the central void and resiliently coupled to the peripheral frame (32) to allow limited resilient movement of the rigid peripheral frame (32) relative to the piston (36).Type: GrantFiled: October 23, 2015Date of Patent: December 15, 2020Assignee: Lavazza Professional North America, LLCInventors: Paul Fletcher, David Knowles, Mark Thompson, Philip Mould, Peter Austin
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Patent number: 10749121Abstract: Compounds comprising phosphorescent metal complexes comprising cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1?,2?-c]quinazoline ligands, or isoelectronic or benzannulated analogs thereof, are described. Organic light emitting diode devices comprising these compounds are also described.Type: GrantFiled: July 15, 2019Date of Patent: August 18, 2020Assignee: UNIVERSAL DISPLAY CORPORATIONInventors: David Knowles, Chun Lin, Peter Mackenzie, Jui-Yi Tsai, Robert W. Walters, Scott Beers, Cory S. Brown, Walter Yeager
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Publication number: 20200126222Abstract: The subject disclosure presents systems and computer-implemented methods for assessing a risk of cancer recurrence in a patient based on a holistic integration of large amounts of prognostic information for said patient into a single comparative prognostic dataset. A risk classification system may be trained using the large amounts of information from a cohort of training slides from several patients, along with survival data for said patients. For example, a machine-learning-based binary classifier in the risk classification system may be trained using a set of granular image features computed from a plurality of slides corresponding to several cancer patients whose survival information is known and input into the system. The trained classifier may be used to classify image features from one or more test patients into a low-risk or high-risk group.Type: ApplicationFiled: October 21, 2019Publication date: April 23, 2020Inventors: Michael Barnes, Srinivas Chukka, David Knowles
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Patent number: 10543979Abstract: A beverage preparation capsule containing a beverage preparation ingredient, having a body with side walls formed from one or more substantially air- and liquid-impermeable sheet materials defining a chamber containing a beverage preparation ingredient and further defining an outlet channel having an upstream end in fluid communication with the chamber for escape of beverage from the chamber. At least a region of the outlet channel is filled by a filtration material for filtering the beverage escaping from the chamber. Also provided is a clamp assembly for preparing a beverage from such a capsule, the clamp assembly comprising two or more clamp members, wherein an inner wall of at least one of the clamp members comprises a concave base surface for receiving the capsule and one or more pressure pads projecting from the concave base surface for selectively constricting a region of the capsule.Type: GrantFiled: June 26, 2017Date of Patent: January 28, 2020Assignee: Lavazza Professional North America, LLCInventors: Peter Austin, Paul Fletcher, David Knowles, Sam Hyde
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Patent number: 10489904Abstract: The subject disclosure presents systems and computer-implemented methods for assessing a risk of cancer recurrence in a patient based on a holistic integration of large amounts of prognostic information for said patient into a single comparative prognostic dataset. A risk classification system may be trained using the large amounts of information from a cohort of training slides from several patients, along with survival data for said patients. For example, a machine-learning-based binary classifier in the risk classification system may be trained using a set of granular image features computed from a plurality of slides corresponding to several cancer patients whose survival information is known and input into the system. The trained classifier may be used to classify image features from one or more test patients into a low-risk or high-risk group.Type: GrantFiled: December 9, 2016Date of Patent: November 26, 2019Assignees: Ventana Medical Systems, Inc., The Board of Trustees of the Leland Stanford Junior UniversityInventors: Michael Barnes, Srinivas Chukka, David Knowles
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Patent number: 10403831Abstract: Compounds comprising phosphorescent metal complexes comprising cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1?,2?-c]quinazoline ligands, or isoelectronic or benzannulated analogs thereof, are described. Organic light emitting diode devices comprising these compounds are also described.Type: GrantFiled: October 16, 2018Date of Patent: September 3, 2019Assignee: Universal Display CorporationInventors: David Knowles, Chun Lin, Peter Mackenzie, Jui-Yi Tsai, Robert W. Walters, Scott Beers, Cory S. Brown, Walter Yeager
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Patent number: 10158090Abstract: Compounds comprising phosphorescent metal complexes comprising cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1?,2?-c]quinazoline ligands, or isoelectronic or benzannulated analogs thereof, are described. Organic light emitting diode devices comprising these compounds are also described.Type: GrantFiled: January 3, 2018Date of Patent: December 18, 2018Assignee: UNIVERSAL DISPLAY CORPORATIONInventors: David Knowles, Chun Lin, Peter Mackenzie, Jui-Yi Tsai, Robert W. Walters, Scott Beers, Cory S. Brown, Walter Yeager
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Patent number: 9893306Abstract: Compounds comprising phosphorescent metal complexes comprising cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1?,2?-c]quinazoline ligands, or isoelectronic or benzannulated analogs thereof, are described. Organic light emitting diode devices comprising these compounds are also described.Type: GrantFiled: July 26, 2017Date of Patent: February 13, 2018Assignee: Universal Display CorporationInventors: David Knowles, Chun Lin, Peter Mackenzie, Jui-Yi Tsai, Robert W. Walters, Scott Beers, Cory S. Brown, Walter Yeager
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Publication number: 20170340160Abstract: A beverage preparation apparatus for preparation of a beverage from a capsule in a clamp assembly (30). The clamp assembly has a first clamp member (31) and a second clamp member, where the inner surfaces of the first clamp member and the second clamp member form a clamp chamber (33) for substantially enclosing and supporting a capsule (10) during beverage preparation. The second clamp member comprises a rigid peripheral frame (32) having a central void and a resilient layer (37) extending across said central void. There is a piston (36) positioned in the central void and resiliently coupled to the peripheral frame (32) to allow limited resilient movement of the rigid peripheral frame (32) relative to the piston (36).Type: ApplicationFiled: October 23, 2015Publication date: November 30, 2017Inventors: Paul Fletcher, David Knowles, Mark Thompson, Philip Mould, Peter Austin
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Publication number: 20170291759Abstract: A beverage preparation capsule containing a beverage preparation ingredient, having a body with side walls formed from one or more substantially air- and liquid-impermeable sheet materials defining a chamber containing a beverage preparation ingredient and further defining an outlet channel having an upstream end in fluid communication with the chamber for escape of beverage from the chamber. At least a region of the outlet channel is filled by a filtration material for filtering the beverage escaping from the chamber. Also provided is a clamp assembly for preparing a beverage from such a capsule, the clamp assembly comprising two or more clamp members, wherein an inner wall of at least one of the clamp members comprises a concave base surface for receiving the capsule and one or more pressure pads projecting from the concave base surface for selectively constricting a region of the capsule.Type: ApplicationFiled: June 26, 2017Publication date: October 12, 2017Inventors: Peter Austin, Paul Fletcher, David Knowles, Sam Hyde
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Patent number: 9722193Abstract: Compounds comprising phosphorescent metal complexes comprising cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1?,2?-c]quinazoline ligands, or isoelectronic or benzannulated analogs thereof, are described. Organic light emitting diode devices comprising these compounds are also described.Type: GrantFiled: November 30, 2016Date of Patent: August 1, 2017Assignee: Universal Display CorporationInventors: David Knowles, Chun Lin, Peter MacKenzie, Jui-Yi Tsai, Robert W. Walters, Scott Beers, Cory S. Brown, Walter Yeager
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Patent number: 9687107Abstract: A beverage preparation capsule containing a beverage preparation ingredient, having a body with side walls formed from one or more substantially air- and liquid-impermeable sheet materials defining a chamber containing a beverage preparation ingredient and further defining an outlet channel having an upstream end in fluid communication with the chamber for escape of beverage from the chamber. At least a region of the outlet channel is filled by a filtration material for filtering the beverage escaping from the chamber. Also provided is a clamp assembly for preparing a beverage from such a capsule, the clamp assembly comprising two or more clamp members, wherein an inner wall of at least one of the clamp members comprises a concave base surface for receiving the capsule and one or more pressure pads projecting from the concave base surface for selectively constricting a region of the capsule.Type: GrantFiled: June 22, 2012Date of Patent: June 27, 2017Assignee: Mars, IncorporatedInventors: Peter Austin, Paul Fletcher, David Knowles, Sam Hyde