Patents by Inventor David Koes

David Koes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROFILIN1:ACTIN INHIBITOR AS AN ANTI-ANGIOGENIC COMPOUND
    Publication number: 20230293490
    Abstract: Disclosed are anti-angiogenic agents that target Pfn1:actin interaction. Also disclosed are compounds for treating ocular diseases or conditions. Further disclosed are compounds for treating cancer.
    Type: Application
    Filed: August 12, 2021
    Publication date: September 21, 2023
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, Sorbonne Université, Centre National de la Recherche Scientifique, INSERM (Institut de la Sante er de la Recherche Medicale)
    Inventors: Partha Roy, Lee McDermott, Abigail E. Allen, David Koes, David M. Gau, Paul G. Francoeur, Xavier Guillonneau
  • 20-HETE FORMATION INHIBITORS
    Publication number: 20220144797
    Abstract: This disclosure provides novel heterocyclic compounds and methods for inhibiting the enzyme CYP4. Further disclosed methods include: a method of inhibiting the biosynthesis of 20-hydroxyeicosatetraenoic acid (20-HETE) in a subject in need thereof and a method of producing neuroprotection and decreased brain damage by preventing cerebral microvascular blood flow impairment and anti-oxidant mechanisms in a subject experiencing or having experienced an ischemic event.
    Type: Application
    Filed: February 7, 2020
    Publication date: May 12, 2022
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Lee Apostle McDermott, David Koes, Samuel M. Poloyac, Shabber Mohammed