Patents by Inventor David Kombo

David Kombo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CFTR
    Publication number: 20220227739
    Abstract: The present disclosure is directed to disclosed compounds that modulate, e.g., address underlying defects in cellular processing of CFTR activity.
    Type: Application
    Filed: August 25, 2021
    Publication date: July 21, 2022
    Inventors: Benito Munoz, Cecilia M. Bastos, Daniel Parks, David Kombo
  • Compounds, compositions, and methods for modulating CFTR
    Patent number: 11136313
    Abstract: The present disclosure is directed to disclosed compounds that modulate, e.g., address underlying defects in cellular processing of CFTR activity.
    Type: Grant
    Filed: December 17, 2019
    Date of Patent: October 5, 2021
    Assignee: Proteostasis Therapeutics, Inc.
    Inventors: Benito Munoz, Cecilia M. Bastos, Daniel Parks, David Kombo
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CFTR
    Publication number: 20200385365
    Abstract: The present disclosure is directed to disclosed compounds that modulate, e.g., address underlying defects in cellular processing of CFTR activity.
    Type: Application
    Filed: December 17, 2019
    Publication date: December 10, 2020
    Inventors: Benito Munoz, Cecilia M. Bastos, Daniel Parks, David Kombo
  • Compounds, compositions, and methods for modulating CFTR
    Patent number: 10550106
    Abstract: The present disclosure is directed to disclosed compounds that modulate, e.g., address underlying defects in cellular processing of CFTR activity.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: February 4, 2020
    Assignee: Proteostasis Therapeutics, Inc.
    Inventors: Benito Munoz, Cecilia M. Bastos, Daniel Parks, David Kombo
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CFTR
    Publication number: 20180291006
    Abstract: The present disclosure is directed to disclosed compounds that modulate, e.g., address underlying defects in cellular processing of CFTR activity.
    Type: Application
    Filed: October 6, 2016
    Publication date: October 11, 2018
    Inventors: Benito Munoz, Cecilia M. Bastos, Daniel Parks, David Kombo
  • NICOTINIC RECEPTOR NON-COMPETITIVE ANTAGONISTS
    Publication number: 20140288169
    Abstract: The present invention relates to compounds that modulate nicotinic receptors as non-competitive antagonists, methods for their synthesis, methods for their use, and their pharmaceutical compositions.
    Type: Application
    Filed: January 5, 2012
    Publication date: September 25, 2014
    Applicant: TARGACEPT, INC.
    Inventors: Srinivasa Rao Akireddy, Scott R. Breining, Matt S. Melvin, Srinivasa V. Murthy, Anatoly A. Mazurov, Balwinder Singh Bhatti, Jon-Paul Strachan, Ronald Joseph Heemstra, Todd Showalter, Yunde Xiao, Philip S. Hammond, Lan Miao, David Kombo, Daniel Yohannes, Jason Speake
  • AMIDES OF DIAZABICYCLOOCTANES AND USES THEREOF
    Publication number: 20110263629
    Abstract: The present invention relates to compounds that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).
    Type: Application
    Filed: September 2, 2009
    Publication date: October 27, 2011
    Applicant: Targacept, Inc.
    Inventors: Jon-Paul Strachan, Balwinder Singh Bhatti, Anatoly Mazurov, Jozef Klucik, Yunde Xiao, Philip S. Hammond, David Kombo, Lan Miao, Jason Daniel Speake, Daniel Yohannes
  • DERIVATIVES OF OXABISPIDINE AS NEURONAL NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS
    Publication number: 20110257168
    Abstract: The present invention relates to compounds of formula (I) that bind to and modulate the activity of neuronal nicotinic acetylcholine receptors, to processes for preparing these compounds, to pharmaceutical compositions containing these compounds, and to methods of using these compounds for treating a wide variety of conditions and disorders, including those associated with dysfunction of the central nervous system (CNS).
    Type: Application
    Filed: July 1, 2009
    Publication date: October 20, 2011
    Applicant: Targacept, Inc.
    Inventors: Srinivasa R. Akireddy, Scott R. Breining, Nikolai Fedorov, David Kombo, Anatoly A. Mazurov, Lan Miao, Srinivasa V. Murthy, Todd Showalter, Yunde Xiao, Daniel Yohannes