Patents by Inventor David Konys

David Konys has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for mediating RNAi in vivo
    Patent number: 8148344
    Abstract: This invention relates to new formulated lipid particles (FLiPs) comprising at least one of a single or double stranded oligonucleotide, where the oligonucleotide has been conjugated to a lipophile and at least one of an emulsion or liposome to which the conjugated oligonucleotide has been aggregated, admixed or associated. These particles have surprisingly been shown to effectively deliver oligonucleotides to heart, lung and muscle where they effect gene silencing.
    Type: Grant
    Filed: March 26, 2009
    Date of Patent: April 3, 2012
    Assignees: Alnylam Pharmaceuticals, Inc., ETH Zurich
    Inventors: Akin Akinc, Tomoko Nakayama, David Konys, Markus Stoffel, Christian Wolfrum
  • COMPOSITIONS AND METHODS FOR MEDIATING RNAI IN VIVO
    Publication number: 20100003317
    Abstract: This invention relates to new formulated lipid particles (FLiPs) comprising at least one of a single or double stranded oligonucleotide, where the oligonucleotide has been conjugated to a lipophile and at least one of an emulsion or liposome to which the conjugated oligonucleotide has been aggregated, admixed or associated. These particles have surprisingly been shown to effectively deliver oligonucleotides to heart, lung and muscle where they effect gene silencing.
    Type: Application
    Filed: March 26, 2009
    Publication date: January 7, 2010
    Inventors: Akin Akinc, Tomoko Nakayama, David Konys, Markus Stoffel, Christian Wolfrum