Patents by Inventor David L. AKEY

David L. AKEY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SINGLE-CHAIN ANTIBODY AGAINST FLAVIVIRUS NS1 PROTEIN
    Publication number: 20240002479
    Abstract: The disclosure is directed to binding agents, e.g., a single chain variable fragment (scFv) that specifically binds to a flavivirus NS1 protein, as well as compositions comprising the binding agent and a method of using such compositions to induce an immune response against a flavivirus (e.g., a dengue virus). The disclosure also provides a conjugate comprising the binding agent, and a recombinant NS1 antigen.
    Type: Application
    Filed: November 23, 2021
    Publication date: January 4, 2024
    Inventors: Janet L. Smith, David L. Akey, William Clay Brown, Eva Harris, Scott B. Biering, P. Robert Beatty
  • Vaccine compositions and uses thereof
    Patent number: 10046045
    Abstract: The present disclosure relates to nonstructural protein 1 (NS1) from flaviviruses and uses thereof. In particular, the present invention relates to diagnostic and therapeutic uses of NS1 to treat and prevent disease caused by flaviviruses.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: August 14, 2018
    Assignees: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, PURDUE RESEARCH FOUNDATION
    Inventors: Janet L. Smith, David L. Akey, W. Clay Brown, Richard J Kuhn
  • VACCINE COMPOSITIONS AND USES THEREOF
    Publication number: 20160317644
    Abstract: The present disclosure relates to nonstructural protein 1 (NS1) from flaviviruses and uses thereof. In particular, the present invention relates to diagnostic and therapeutic uses of NS1 to treat and prevent disease caused by flaviviruses.
    Type: Application
    Filed: December 19, 2014
    Publication date: November 3, 2016
    Inventors: Janet L. SMITH, David L. AKEY, W. Clay BROWN, Richard J KUHN