Abstract: Provided herein are compounds of the Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, X1, X2, X3, X4, Ring D, and E have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.

Abstract: A computerized method and system for providing enhanced help messages for equipment operation is described herein. A device having a processor automatically detects an error condition in the device, and determines that the error condition requires operator action. An appropriate message is selected that indicates a required operator action corresponding to the error condition. The message is configured to include a scannable barcode. The scannable barcode includes a website link to a website having more detailed information to assist an operator in performing the operator action. The message is displayed on a screen so that the operator can scan the barcode with his mobile device, and see the more detailed information on how to perform the required operator action. Alternatively, the message is configured as radio frequency data to be transmitted by the equipment using near field communication (NFC) technology to a mobile device having an NFC receiver.

Abstract: A grease composition comprises an effective amount of a lubricating oil containing an imide or pyrrolidone thickening agent or an imide or pyrrolidone thickening agent comprising a metal salt of a carboxylic acid in combination with a bimetal phthalate complexing agent, such as dilithium terephthalate. The presence of the complexing agent results in a grease having properties superior to that of a similar grease without the complexing agent. Preferred complexing agents are dimetal terephthalates in which the metal is an alkali or alkaline earth metal and is the same metal as is present in the thickener. An example is a combination of a calcium or lithium salt of the reaction product of trimellitic anhydride with a hydrogenated rapeseed amine and a dilithium terephthalate complexing agent.