Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.

Abstract: A defoaming composition comprising an organo siloxane polymer, an aliphatic alcohol such as 2-ethylhexanol and, optionally, a liquid carrier which can be added to a coking drum in a delayed coking process to reduce foaming. In cases where the feed stock used in the delayed coking process contains greater than one half percent total sulfur, defoaming in the coking drum can be accomplished by adding an aliphatic alcohol such as 2-ethylhexanol.

Abstract: A tank having an outlet conduit is provided with a valve assembly for controlling the flow of a fluid through the outlet conduit. The valve assembly includes a first valve element cooperating with a first valve seat formed by the conduit to provide a first valve. A second valve element cooperates with a second valve seat formed by the first valve element to provide a second valve. Valve opening means are pivotal on the tank to selectively open the second valve or the first and second valve to permit the discharge of fluid volumes of different magnitudes.Both the first and second valve elements can be heavier than equivalent volumes of the fluid so a first float is provided to maintain the first valve in its open state and a second float is provided to maintain the second valve in its open state. As the surface of the fluid descends, the respective floats close their respective valves at fluid levels dependent upon the initial height of the floats in the tank.