Abstract: A medical device for treating aortic insufficiency (and associated aneurysms or defects of any other vessel associated with a valve) includes a support structure, a stent, a prosthetic valve and a deflector. Generally, the support structure is configured to cooperate with the prosthetic valve to pinch the native valve therebetween and provide an anchor for the stent which extends into the aorta and supports the deflector which is positioned to abate blood flow against the aneurysm.

Abstract: A method of capturing and macerating particles in a blood vessel is provided. A vascular filter device is implanted in the blood vessel at a treatment site. The vascular filter device comprises a filter body and an agitation member disposed within the filter body. Movement of the agitation member acts on particles trapped within the filter body for enhancing the dissolution of the particles, thereby reducing the likelihood of filter occlusion and improving the flow of blood through the vessel. The vascular filter device is preferably collapsible for percutaneous delivery to a treatment site. The agitation member is preferably rotatably coupled to the filter body. A power source is provided for moving the agitation member. In various examples, the power source may take the form of an energy storage device, a drive catheter, or a magnetic field.

Abstract: Methods for treating a defective mitral valve are provided. One preferred method comprises attaching opposing ends of a tether to opposing regions of the mitral valve annulus. The tether is advanced percutaneously into the left atrium by a therapy catheter. Vacuum ports may be provided on the therapy catheter for grasping tissue along the mitral valve annulus. The therapy catheter may also include advanceable needles for passing the tether through the tissue. Alternatively, the ends of the tether may be attached to fastener elements which are secured to the tissue. Tension in the tether pulls the opposing regions of the mitral valve annulus into closer proximity for improving mitral valve function.

Abstract: A prosthetic insert member for improving the function of a mitral valve is disclosed. The insert member is configured for insertion between leaflets of mitral valve. The insert member has an elongated cross-sectional profile for conforming to the opening in the mitral valve. The device also includes an anchoring member for attachment to heart tissue for maintaining the insert member in the mitral valve. In operation, the insert member fills the opening between the leaflets of the mitral valve and reduces regurgitation while preferably allowing the leaflets to function in a substantially normal manner. In one embodiment, the insert member is formed with a valve member disposed in a passageway for allowing blood to pass through the insert member in one direction.

Abstract: A method of reducing ventricular dilation comprises placing one or more cardiac bridges into vessels extending along a length of the ventricle. Each cardiac bridge preferably includes a pair of anchors and a bridge member secured therebetween. The tension in the bridge member compresses the ventricle and thereby reduces the dilation along the ventricle wall. In another embodiment, the bridge member is tensioned to reshape the left ventricle for reducing tension on the chordae tendinae in the heart for improving valve function.

Abstract: A device and method for reducing ventricular dilation by placing one or more cardiac bridges into vessels extending along a length of the ventricle. Each cardiac bridge preferably includes a pair of anchors and a bridge member secured therebetween. The tension in the bridge member is increased to compress the ventricle and thereby reduce the dilation. In another embodiment, the bridge member is tensioned to reshape the left ventricle for reducing tension on the chordae tendinae in the heart to improve valve function.

Abstract: Devices and methods for reshaping a mitral valve annulus are provided. One preferred device is configured for deployment in the right atrium and is shaped to apply a force along the atrial septum. The device causes the atrial septum to deform and push the anterior leaflet of the mitral valve in a posterior direction for reducing mitral valve regurgitation. Another preferred device is deployed in the left ventricular outflow tract at a location adjacent the aortic valve. The device is expandable for urging the anterior leaflet toward the posterior leaflet. Another preferred device comprises a tether configured to be attached to opposing regions of the mitral valve annulus.

Abstract: A method of capturing and macerating particles in a blood vessel is provided. A vascular filter device is implanted in the blood vessel at a treatment site. The vascular filter device comprises a filter body and an agitation member disposed within the filter body. Movement of the agitation member acts on particles trapped within the filter body for enhancing the dissolution of the particles, thereby reducing the likelihood of filter occlusion and improving the flow of blood through the vessel. The vascular filter device is preferably collapsible for percutaneous delivery to a treatment site. The agitation member is preferably rotatably coupled to the filter body. A power source is provided for moving the agitation member. In various examples, the power source may take the form of an energy storage device, a drive catheter, or a magnetic field.

Abstract: A vascular filter for capturing and breaking apart particles in the blood. The vascular filter includes a filter body and an agitation member disposed within the filter body. Movement of the agitation member acts on particles trapped within the filter body for enhancing the dissolution of the particles, thereby reducing the likelihood of filter occlusion and improving the flow of blood through the vessel. The vascular filter is preferably collapsible for percutaneous delivery to a treatment site. The agitation member is preferably rotatably coupled to the filter body and a flow receiving member is provided for causing the agitation member to rotate. A clutch mechanism may be provided such that the agitation member only rotates when a particle, such as a blood clot, is trapped within the filter body.

Abstract: Devices and methods for reshaping a mitral valve annulus are provided. One preferred device is configured for deployment in the right atrium and is shaped to apply a force along the atrial septum. The device causes the atrial septum to deform and push the anterior leaflet of the mitral valve in a posterior direction for reducing mitral valve regurgitation. Another preferred device is deployed in the left ventricular outflow tract at a location adjacent the aortic valve. The device is expandable for urging the anterior leaflet toward the posterior leaflet. Another preferred device comprises a tether configured to be attached to opposing regions of the mitral valve annulus.

Abstract: A device and method for reducing ventricular dilation by placing one or more cardiac bridges into vessels extending along a length of the ventricle. Each cardiac bridge preferably includes a pair of anchors and a bridge member secured therebetween. The tension in the bridge member is increased to compress the ventricle and thereby reduce the dilation. In another embodiment, the bridge member is tensioned to reshape the left ventricle for reducing tension on the chordae tendinae in the heart to improve valve function.

Abstract: An apparatus, system, and method for repairing openings such as septal defects includes advancing a catheter to the site of the defect, grasping opposing edges of the defect, passing one or more suture lines through the opposing edges, tightening the suture lines, and deploying and expanding a fastener to secure the suture lines and close the defect. The fastener can include tissue-growth-inducing materials to encourage tissue growth onto or into the fastener and/or suture. The fastener includes a locking clip portion and a plug portion, which may be an expandable portion and/or tissue-growth-inducing portion.

Abstract: A device and methods for improving the function of a heart valve, such as an aortic valve, is disclosed. In one embodiment, the device includes an insert member configured for insertion between leaflets of an aortic valve. The insert member preferably includes three radial arms extending outwardly from a central portion. The device also includes an anchoring member which is coupled to the insert member and configured for maintaining the insert member within the heart valve. In operation, each of the arms fills gaps between heart valve leaflets, thereby minimizing or preventing regurgitation through the heart valve.

Abstract: A central database provides a location for creating and storing samples of known television commercials. The database of commercial samples is downloaded to a set-top box via a communicate link. The set-top box incorporates a processor for comparing a television signal with the database of known commercial messages to detect the presence of commercial messages. The set-top box may be used to control a recording unit to stop recording for the duration of the commercial message or flag the commercial message for muting or manual skipping during playback. Using this system, the user has the ability to positively detect commercial messages and eliminate the commercials from viewing if desired.