Abstract: This document provides materials and methods for identifying and quantifying AIM polypeptides in a sample using mass spectrometry techniques. For example, methods of using mass spectrometry to identify and quantify AIM polypeptides in a serum sample are provided. In some cases, quantification of AIM polypeptides can be used to diagnose and/or treat patients having a disease or disorder characterized by altered (e.g., increased or decreased) AIM polypeptide levels.

Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.

Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.

Abstract: This document relates to methods for identifying one or more immunoglobulin free light chains in a sample using mass spectrometry. For example, this document relates to a method for identifying one or more immunoglobulin free light chains in a sample that includes (a) providing a sample; (b) subjecting the sample to a mass spectrometry technique to obtain a mass spectrum of the sample; and (c) identifying the presence of the one or more immunoglobulin free light chains.

Abstract: This document relates to materials and methods for identifying and monitoring immunoglobulin cleavage (e.g., IgG cleavage) in a sample, such as a biological sample, using mass spectrometry techniques.

Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.

Abstract: This document provides materials and methods for identifying and quantifying AIM polypeptides in a sample using mass spectrometry techniques. For example, methods of using mass spectrometry to identify and quantify AIM polypeptides in a serum sample are provided. In some cases, quantification of AIM polypeptides can be used to diagnose and/or treat patients having a disease or disorder characterized by altered (e.g., increased or decreased) AIM polypeptide levels.

Abstract: This document relates to materials and methods for identifying and monitoring immunoglobulin J chains in a sample, such as a biological sample, using mass spectrometry techniques.

Abstract: This document provides materials and methods for identifying and/or quantifying immunoglobulin heavy chains (e.g., IgG heavy chains) in a sample, such as a biological sample, using mass spectrometry techniques. For example, mass spectrometry techniques that can be used to identify and/or quantify IgG heavy chain acid hydrolysis products in a serum sample without the need for any IgG cleavage reagents (e.g., enzymes) are provided.

Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.

Abstract: This document relates to methods for quantifying antibody therapeutics using mass spectrometry techniques.

Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.

Abstract: This document relates to materials and methods for identifying and monitoring immunoglobulin cleavage (e.g., IgG cleavage) in a sample, such as a biological sample, using mass spectrometry techniques.

Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.

Abstract: An anti-immunoglobulin specific antibody (or fragment thereof), characterised that the antibody or fragment thereof comprises one or more non-disulphide cross-links between at least one heavy chain or fragment thereof and at least one light chain or fragment thereof of the antibody or fragment thereof. A method purifying an anti-immunoglobulin specific antibody (or fragment thereof), characterised that the antibody or fragment thereof comprises one or more non-disulphide cross-links between at least one heavy chain or fragment thereof and at least one light chain or fragment thereof of the antibody or fragment thereof.

Abstract: This document relates to methods for identifying one or more immunoglobulin free light chains in a sample using mass spectrometry. For example, this document relates to a method for identifying one or more immunoglobulin free light chains in a sample that includes (a) providing a sample; (b) subjecting the sample to a mass spectrometry technique to obtain a mass spectrum of the sample; and (c) identifying the presence of the one or more immunoglobulin free light chains.

Abstract: This document relates to methods for quantifying antibody therapeutics using mass spectrometry techniques.

Abstract: This document relates to methods for detecting and quantifying heavy and light chains of immunoglobulin using mass spectrometry techniques.

Abstract: Disclosure herein are methods for determining whether or not an immunoglobulin is present above the polyclonal background level in a biological sample, and methods for determining whether an immunoglobulin contains a kappa or lambda light chain. These methods are useful for screening biological samples for the presence or absence of monoclonal gammopathy, and for diagnosing and monitoring monoclonal gammopathy in a subject.

Abstract: A mass flow grain monitor is located adjacent the upper end of the clean grain elevator assembly of a harvester and includes a load cell having a member that is subject to slight deformation under loads for use in generating an output signal that is proportional to the load. As the grain flow reaches the top of the elevator assembly, its direction is changed such that a centrifugal force is exerted by the moving flow that is proportional to the mass of the grain flow at that instant. Such centrifugal force is directed vertically against the deformable member of the load cell which is itself generally horizontally disposed when the harvester is on level ground so that the entire weight of the deformable member can be treated as tare and zeroed out of the system when it is calibrated with the harvester on level ground.