Patents by Inventor David L. Shelton

David L. Shelton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140294829
    Abstract: The present invention relates generally to methods of using anti-NGF antibodies in the treatment of various NGF-related disorders, including pain, asthma, arthritis and psoriasis. The methods are effective in treating these disorders in a patient without having a significant adverse effect on the immune system of the patient.
    Type: Application
    Filed: March 24, 2014
    Publication date: October 2, 2014
    Applicant: GENENTECH, INC.
    Inventor: David L. Shelton
  • Patent number: 8557245
    Abstract: The invention features methods and compositions for preventing or treating bone cancer pain including cancer pain associated with bone metastasis by administering an antagonist of nerve growth factor (NGF). The NGF antagonist may be an anti-NGF (such as anti-hNGF) antibody that is capable of binding hNGF.
    Type: Grant
    Filed: June 13, 2012
    Date of Patent: October 15, 2013
    Assignees: Rinat Neuroscience Corp., Regents of The University of Minnesota
    Inventors: David L. Shelton, Patrick William Mantyh
  • Publication number: 20130004495
    Abstract: The present invention relates generally to methods of using anti-NGF antibodies in the treatment of various NGF-related disorders, including pain, asthma, arthritis and psoriasis. The methods are effective in treating these disorders in a patient without having a significant adverse effect on the immune system of the patient.
    Type: Application
    Filed: September 6, 2012
    Publication date: January 3, 2013
    Applicant: Genentech, Inc.
    Inventor: David L. Shelton
  • Publication number: 20120315271
    Abstract: The invention features methods and compositions for preventing or treating bone cancer pain including cancer pain associated with bone metastasis by administering an antagonist of nerve growth factor (NGF). The NGF antagonist may be an anti-NGF (such as anti-hNGF) antibody that is capable of binding hNGF.
    Type: Application
    Filed: June 13, 2012
    Publication date: December 13, 2012
    Inventors: David L. Shelton, Patrick William Mantyh
  • Patent number: 8226951
    Abstract: The invention features methods and compositions for preventing or treating bone cancer pain including cancer pain associated with bone metastasis by administering an antagonist of nerve growth factor (NGF). The NGF antagonist may be an anti-NGF (such as anti-hNGF) antibody that is capable of binding hNGF.
    Type: Grant
    Filed: June 6, 2011
    Date of Patent: July 24, 2012
    Assignee: Pfizer Inc.
    Inventors: David L. Shelton, Patrick William Mantyh
  • Publication number: 20120045443
    Abstract: The invention concerns agonist anti-trkC monoclonal antibodies which mimic certain biological activities of NT-3, the native ligand of trkC. The invention further concerns the use of such antibodies in the prevention and/or treatment of cellular degeneration, including nerve cell damage associated with acute nervous cell system injury and chronic neurodegenerative diseases, including peripheral neuropathy.
    Type: Application
    Filed: August 5, 2011
    Publication date: February 23, 2012
    Inventors: Brigitte Devaux, Jo-Anne Hongo, Leonard G. Presta, David L. Shelton
  • Publication number: 20110268725
    Abstract: The present invention relates generally to methods of using anti-NGF antibodies in the treatment of various NGF-related disorders, including asthma, arthritis and psoriasis. The methods are effective in treating these disorder in a patient without having a significant adverse effect on the immune system of the patient.
    Type: Application
    Filed: April 19, 2011
    Publication date: November 3, 2011
    Inventor: David L. Shelton
  • Patent number: 8034346
    Abstract: The present invention features methods for treating or preventing pain comprising administering an amount of a nerve growth factor antagonist (such as an anti-NGF antibody) and an amount of an NSAID such that together they provide effective pain relief. The invention also features compositions comprising a nerve growth factor antagonist and an NSAID and kits containing the same.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: October 11, 2011
    Assignee: Rinat Neuroscience Corp.
    Inventors: David L. Shelton, German J. Vergara, Carole M. Loo
  • Publication number: 20110243961
    Abstract: The invention features methods and compositions for preventing or treating bone cancer pain including cancer pain associated with bone metastasis by administering an antagonist of nerve growth factor (NGF). The NGF antagonist may be an anti-NGF (such as anti-hNGF) antibody that is capable of binding hNGF.
    Type: Application
    Filed: June 6, 2011
    Publication date: October 6, 2011
    Inventors: David L. Shelton, Patrick William Mantyh
  • Patent number: 8007800
    Abstract: The invention features methods and compositions for preventing or treating bone cancer pain including cancer pain associated with bone metastasis by administering an antagonist of nerve growth factor (NGF). The NGF antagonist may be an anti-NGF (such as anti-hNGF) antibody that is capable of binding hNGF.
    Type: Grant
    Filed: March 16, 2009
    Date of Patent: August 30, 2011
    Assignee: Pfizer Inc.
    Inventors: David L. Shelton, Patrick William Mantyh
  • Patent number: 7985413
    Abstract: Microbiological control is achieved by continuously and inexpensively dosing water in contact with biofilm, or that comes into contact with biofilm, using a highly effective biocide that provides very effective microbiocidal control of planktonic microorganisms and of biofilm species, even where the biofilm infestations have been in existence for long periods of time and thus have encased themselves in a substantial quantity of slimy defensive polysaccharide layers or films. In addition, the biocide used makes possible significant reduction in copper and/or iron surfaces in contact with the water as compared to N,N?-bromochloro-5,5-dimethyl hydantoin. Still other advantages are made possible by the described technology.
    Type: Grant
    Filed: March 5, 2009
    Date of Patent: July 26, 2011
    Assignee: Albemarle Corporation
    Inventors: Jonathan N. Howarth, Christopher J. Nalepa, Michael J. Sanders, David L. Shelton
  • Publication number: 20100254990
    Abstract: The present invention relates generally to methods of using anti-NGF antibodies in the treatment of various NGF-related disorders, including asthma, arthritis and psoriasis. The methods are effective in treating these disorder in a patient without having a significant adverse effect on the immune system of the patient.
    Type: Application
    Filed: April 6, 2010
    Publication date: October 7, 2010
    Inventor: David L. Shelton
  • Publication number: 20100143355
    Abstract: The present invention features methods for treating or preventing pain comprising administering an amount of a nerve growth factor antagonist (such as an anti-NGF antibody) and an amount of an NSAID such that together they provide effective pain relief. The invention also features compositions comprising a nerve growth factor antagonist and an NSAID and kits containing the same.
    Type: Application
    Filed: December 22, 2009
    Publication date: June 10, 2010
    Inventors: DAVID L. SHELTON, GERMAN J. VERGARA, CAROLE M. LOO
  • Patent number: 7727527
    Abstract: The present invention relates generally to methods of using anti-NGF antibodies in the treatment of various NGF-related disorders, including asthma, arthritis and psoriasis. The methods are effective in treating these disorders in a patient without having a significant adverse effect on the immune system of the patient.
    Type: Grant
    Filed: May 9, 2002
    Date of Patent: June 1, 2010
    Assignee: Genentech, Inc.
    Inventor: David L. Shelton
  • Patent number: 7655231
    Abstract: The present invention features methods for treating or preventing pain comprising administering an amount of a nerve growth factor antagonist (such as an anti-NGF antibody) and an amount of an NSAID such that together they provide effective pain relief. The invention also features compositions comprising a nerve growth factor antagonist and an NSAID and kits containing the same.
    Type: Grant
    Filed: February 19, 2004
    Date of Patent: February 2, 2010
    Assignee: Pfizer Inc.
    Inventors: David L. Shelton, German J. Vergara, Carole M. Loo
  • Publication number: 20100003261
    Abstract: The invention concerns agonist anti-trkC monoclonal antibodies which mimic certain biological activities of NT-3, the native ligand of trkC. The invention further concerns the use of such antibodies in the prevention andior treatment of cellular degeneration, including nerve cell damage associated with acute nervous cell system injury and chronic neurodegenerative diseases, including peripheral neuropathy.
    Type: Application
    Filed: June 4, 2009
    Publication date: January 7, 2010
    Inventors: Brigitte Devaux, Jo-Anne Hongo, Leonard G. Presta, David L. Shelton
  • Patent number: 7615383
    Abstract: The invention concerns agonist anti-trkC monoclonal antibodies which mimic certain biological activities of NT-3, the native ligand of trkC. The invention further concerns the use of such antibodies in the prevention and/or treatment of cellular degeneration, including nerve cell damage associated with acute nervous cell system injury and chronic neurodegenerative diseases, including peripheral neuropathy.
    Type: Grant
    Filed: October 16, 2006
    Date of Patent: November 10, 2009
    Assignee: Genentech, Inc.
    Inventors: Brigitte Devaux, Jo-Anne Hongo, Leonard G. Presta, David L. Shelton
  • Publication number: 20090252744
    Abstract: The invention features methods and compositions for preventing or treating bone cancer pain including cancer pain associated with bone metastasis by administering an antagonist of nerve growth factor (NGF). The NGF antagonist may be an anti-NGF (such as anti-hNGF) antibody that is capable of binding hNGF.
    Type: Application
    Filed: March 16, 2009
    Publication date: October 8, 2009
    Inventors: David L. Shelton, Patrick William Mantyh
  • Patent number: 7579018
    Abstract: Microbiological control is achieved by continuously and inexpensively dosing water in contact with biofilm, or that comes into contact with biofilm, using a highly effective biocide that provides very effective microbiocidal control of planktonic microorganisms and of biofilm species, even where the biofilm infestations have been in existence for long periods of time and thus have encased themselves in a substantial quantity of slimy defensive polysaccharide layers or films. In addition, the biocide used makes possible significant reduction in copper and/or iron surfaces in contact with the water as compared to N,N?-bromochloro- 5,5-dimethyl hydantoin. Still other advantages are made possible by the described technology.
    Type: Grant
    Filed: October 17, 2003
    Date of Patent: August 25, 2009
    Assignee: Albemarle Corporation
    Inventors: Jonathan N. Howarth, Christopher J. Nalepa, Michael J. Sanders, David L. Shelton
  • Patent number: 7569364
    Abstract: The invention concerns anti-NGF antibodies (such as anti-NGF antagonist antibodies), and polynucleotides encoding the same. The invention further concerns use of such antibodies and/or polynucleotides in the treatment and/or prevention of pain, including post-surgical pain, rheumatoid arthritis pain, and osteoarthritis pain.
    Type: Grant
    Filed: April 11, 2005
    Date of Patent: August 4, 2009
    Assignee: Pfizer Inc.
    Inventors: Arnon Rosenthal, David L. Shelton, Patricia A. Walicke