Patents by Inventor David L. Shelton

David L. Shelton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5910574
    Abstract: The invention concerns human trkB and trkC receptors and their functional derivatives. The invention further concerns immunoadhesins comprising trk receptor sequences fused to immunoglobulin sequences.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: June 8, 1999
    Assignee: Genentech, Inc.
    Inventors: Leonard G. Presta, David L. Shelton, Roman Urfer
  • Patent number: 5900696
    Abstract: An incandescent lamp with shock resisting supports having filament, first support rod, envelope, spacer, spacer, cap seal, and block is disclosed. The incandescent lamp with shock resisting supports yielding an incandescent lamp with a heavy filament structure supported by two support rods protected by a shock conditioning spacer and spring.
    Type: Grant
    Filed: November 3, 1993
    Date of Patent: May 4, 1999
    Assignee: Osramisylvania Inc.
    Inventors: Jeffrey P. Buschmann, David L. Shelton
  • Patent number: 5891650
    Abstract: An assay for measuring activation (i.e., autophosphorylation) of a tyrosine kinase receptor of interest is disclosed.(a) A first solid phase is coated with a substantially homogeneous population of cells so that the cells adhere to the first solid phase. The cells have either an endogenous tyrosine kinase receptor or have been transformed with DNA encoding a receptor or "receptor construct" and the DNA has been expressed so that the receptor or receptor construct is presented in the cell membranes of the cells.(b) A ligand is then added to the solid phase having the adhering cells, such that the tyrosine kinase receptor is exposed to the ligand.(c) Following exposure to the ligand, the adherent cells are solubilized, thereby releasing cell lysate.(d) A second solid phase is coated with a capture agent which binds specifically to the tyrosine kinase receptor, or, in the case of a receptor construct, to the flag polypeptide.
    Type: Grant
    Filed: May 15, 1995
    Date of Patent: April 6, 1999
    Assignee: Genentech Incorporated
    Inventors: Paul J. Godowski, Melanie R. Mark, Michael D. Sadick, David L. Shelton, Wai Lee Tan Wong
  • Patent number: 5877016
    Abstract: The invention concerns human trkB and trkC receptors and their functional derivatives. The invention further concerns inmunoadhesins comprising trk receptor sequences fused to immunoglobulin sequences.
    Type: Grant
    Filed: August 5, 1994
    Date of Patent: March 2, 1999
    Assignee: Genentech, Inc.
    Inventors: Leonard G. Presta, David L. Shelton, Roman Urfer
  • Patent number: 5844092
    Abstract: The invention concerns human trkB and trkC receptors and their functional derivatives. The invention further concerns immunoadhesins comprising trk receptor sequences fused to immunoglobulin sequences.
    Type: Grant
    Filed: December 20, 1994
    Date of Patent: December 1, 1998
    Assignee: Genentech, Inc.
    Inventors: Leonard G. Presta, David L. Shelton, Roman Urfer
  • Patent number: 5766863
    Abstract: An assay for measuring activation (i.e., autophosphorylation) of a tyrosine kinase receptor of interest is disclosed.(a) A first solid phase is coated with a substantially homogeneous population of cells so that the cells adhere to the first solid phase. The cells have either an endogenous tyrosine kinase receptor or have been transformed with DNA encoding a receptor or "receptor construct" and the DNA has been expressed so that the receptor or receptor construct is presented in the cell membranes of the cells.(b) A ligand is then added to the solid phase having the adhering cells, such that the tyrosine kinase receptor is exposed to the ligand.(c) Following exposure to the ligand, the adherent cells are solubilized, thereby releasing cell lysate.(d) A second solid phase is coated with a capture agent which binds specifically to the tyrosine kinase receptor, or, in the case of a receptor construct, to the flag polypeptide.
    Type: Grant
    Filed: August 5, 1995
    Date of Patent: June 16, 1998
    Assignee: Genentech, Inc.
    Inventors: Paul J. Godowski, Melanie R. Mark, Michael D. Sadick, David L. Shelton, Wai Lee Tan Wong
  • Patent number: 5057241
    Abstract: Disclosed are thickened single phase detergent compositions for cleaning the body which have modified pseudoplastic characteristics because they contain a combination of two polymers which make them especially suitable for dispensing from containers which impart shear to the composition during dispensing and to methods for making such compositions. The compositions contain from about 1-20% anionic, nonionic and/or amphoteric surfactants and preferably contain anionic surfactants. The polymer imparting pseudoplastic characteristics is about 0.3 to 1.5% of an addition polymer of a C.sub.3 -C.sub.8 alpha, beta-monoethylenically unsaturated mono- or dicarboxylic acid, at least one monoethylenically unsaturated copolymerizable monomer lacking surfactant capacity and at least one monomer possessing surfactant capacity which is the reaction product of a monoethylenically unsaturated monomer with a nonionic surfactant compound.
    Type: Grant
    Filed: November 16, 1988
    Date of Patent: October 15, 1991
    Assignee: S. C. Johnson & Son, Inc.
    Inventors: Colleen M. Merritt, Jerry L. Newman, David L. Shelton, Sheng-Liang Tsaur
  • Patent number: 4822604
    Abstract: A clear, therapeutic hair care composition is presented having a low pH and useful in the local treatment of dandruff, seborrheic dermatitis and psoriasis of the scalp which resists oxidative decomposition. The shampoo is comprised of a detergent shampoo base, a therapeutic amount of a keratolytic agent and a keratolytic stabilizing agent to stabilize the keratolytic agent against oxidative decoloration decomposition catalyzed by ultraviolet radiation exposure. The keratolytic agent is preferably a salicylate and preferably salicylic acid and the keratolytic stabilizing agent is a tertiary amine.
    Type: Grant
    Filed: May 20, 1985
    Date of Patent: April 18, 1989
    Assignee: S. C. Johnson & Son, Inc.
    Inventors: Donald W. Knoll, David L. Shelton, Thomas J. Szymczak
  • Patent number: 4504465
    Abstract: Stable, single phase soap gel cosmetic stick compositions comprising a polyhydric aliphatic alcohol, an ethylene oxide and/or propylene oxide condensation product and soap. Such cosmetic sticks are easily processed as well as being stable.
    Type: Grant
    Filed: June 30, 1980
    Date of Patent: March 12, 1985
    Assignee: The Proctor & Gamble Company
    Inventors: Ronald L. Sampson, David L. Shelton
  • Patent number: 4370319
    Abstract: Skin conditioning compositions comprising an alkali metal phosphoric acid ester salt of a partial glyceride, silicone fluid, a long chain alkyl ester of a fatty acid, an emollient material, an emulsifier and water. The phosphated glyceride and the dimethicone fluid serve to provide greater retention of the conditioning composition on the skin.
    Type: Grant
    Filed: March 20, 1981
    Date of Patent: January 25, 1983
    Assignee: The Procter & Gamble Company
    Inventors: Carole N. Chapin, Gary R. Kelm, David L. Shelton
  • Patent number: 4202879
    Abstract: Stable, three-phase antiperspirant stick compositions having (1) a solid, shearable antiperspirant phase, (2) a gel phase comprising a polyhydric aliphatic alcohol gelled with soap, and (3) a barrier phase of specified minimum thickness separating the antiperspirant and gel phases comprising a water-insoluble, alcohol-insoluble, high melting point wax and liquid emollient and which is relatively free of particulate materials. Such antiperspirant sticks provide effective antiperspirant performance as well as desirable application characteristics.
    Type: Grant
    Filed: July 13, 1978
    Date of Patent: May 13, 1980
    Assignee: The Procter & Gamble Company
    Inventor: David L. Shelton