Patents by Inventor David L. Tennent
David L. Tennent has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8062881Abstract: Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm2 are achieved by: (1) applying a coating solution composed of a solvent and a non-ionic surfactant having a HLB number of less than 5 to the surface; and (2) drying the surface to remove the solvent and thereby bring the surfactant into direct contact with the hydrophobic polymer. The combination of a low HLB number and the drying step have been found to produce low binding surfaces which can withstand multiple washes with water and/or protein-containing solutions Alternatively, the low binding surfaces can be produced by applying the non-ionic surfactant to the mold surfaces which contact molten polymer and form the polymer into a desired shape, e.g., into a multi-well plate, a pipette tip, or the like. Further, the low binding surfaces may be produced by incorporating non-soluble, non-ionic surfactants having an HLB number of less than or equal to 10 into a polymer blend prior to molding the article.Type: GrantFiled: July 8, 2010Date of Patent: November 22, 2011Assignee: Corning IncorporatedInventors: Dana Craig Bookbinder, Edward John Fewkes, Jr., James Arthur Griffin, Frances M. Smith, David L. Tennent
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Publication number: 20100280174Abstract: Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm2 are achieved by: (1) applying a coating solution composed of a solvent and a non-ionic surfactant having a HLB number of less than 5 to the surface; and (2) drying the surface to remove the solvent and thereby bring the surfactant into direct contact with the hydrophobic polymer. The combination of a low HLB number and the drying step have been found to produce low binding surfaces which can withstand multiple washes with water and/or protein-containing solutions Alternatively, the low binding surfaces can be produced by applying the non-ionic surfactant to the mold surfaces which contact molten polymer and fault the polymer into a desired shape, e.g., into a multi-well plate, a pipette tip, or the like. Further, the low binding surfaces may be produced by incorporating non-soluble, non-ionic surfactants having an HLB number of less than or equal to 10 into a polymer blend prior to molding the article.Type: ApplicationFiled: July 8, 2010Publication date: November 4, 2010Inventors: Dana Craig Bookbinder, Edward John Fewkes, JR., James Arthur Griffin, Frances M. Smith, David L. Tennent
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Patent number: 7776572Abstract: Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm2 are achieved by: (1) applying a coating solution composed of a solvent and a non-ionic surfactant having a HLB number of less than 5 to the surface; and (2) drying the surface to remove the solvent and thereby bring the surfactant into direct contact with the hydrophobic polymer. The combination of a low HLB number and the drying step have been found to produce low binding surfaces which can withstand multiple washes with water and/or protein-containing solutions Alternatively, the low binding surfaces can be produced by applying the non-ionic surfactant to the mold surfaces which contact molten polymer and form the polymer into a desired shape, e.g., into a multi-well plate, a pipette tip, or the like. Further, the low binding surfaces may be produced by incorporating non-soluble, non-ionic surfactants having an HLB number of less than or equal to 10 into a polymer blend prior to molding the article.Type: GrantFiled: February 16, 2007Date of Patent: August 17, 2010Assignee: Corning IncorporatedInventors: Dana Craig Bookbinder, Edward John Fewkes, Jr., James Arthur Griffin, Frances M. Smith, David L. Tennent
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Publication number: 20080145280Abstract: Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm2 are achieved by: (1) applying a coating solution composed of a solvent and a non-ionic surfactant having a HLB number of less than 5 to the surface; and (2) drying the surface to remove the solvent and thereby bring the surfactant into direct contact with the hydrophobic polymer. The combination of a low HLB number and the drying step have been found to produce low binding surfaces which can withstand multiple washes with water and/or protein-containing solutions. Alternatively, the low binding surfaces can be produced by applying the non-ionic surfactant to the mold surfaces which contact molten polymer and form the polymer into a desired shape, e.g., into a multi-well plate, a pipette tip, or the like. Further, the low binding surfaces may be produced by incorporating non-soluble, non-ionic surfactants having an HLB number of less than or equal to 10 into a polymer blend prior to molding the article.Type: ApplicationFiled: October 30, 2007Publication date: June 19, 2008Inventors: Dana Craig Bookbinder, Edward John Fewkes, James Arthur Griffin, Frances M. Smith, David L. Tennent
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Patent number: 7312057Abstract: Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm2 are achieved by: (1) applying a coating solution composed of a solvent and a non-ionic surfactant having a HLB number of less than 5 to the surface; and (2) drying the surface to remove the solvent and thereby bring the surfactant into direct contact with the hydrophobic polymer. The combination of a low HLB number and the drying step have been found to produce low binding surfaces which can withstand multiple washes with water and/or protein-containing solutions Alternatively, the low binding surfaces can be produced by applying the non-ionic surfactant to the mold surfaces which contact molten polymer and form the polymer into a desired shape, e.g., into a multi-well plate, a pipette tip, or the like. Further, the low binding surfaces may be produced by incorporating non-soluble, non-ionic surfactants having an HLB number of less than or equal to 10 into a polymer blend prior to molding the article.Type: GrantFiled: March 3, 2003Date of Patent: December 25, 2007Assignee: Corning IncorporatedInventors: Dana Craig Bookbinder, Edward John Fewkes, Jr., James Arthur Griffin, Frances M. Smith, David L. Tennent
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Patent number: 6732551Abstract: A method for making silica includes delivering a silica precursor comprising a pseudohalogen to a conversion site and passing the silica precursor through a flame to produce silica soot.Type: GrantFiled: May 4, 2001Date of Patent: May 11, 2004Assignee: Corning IncorporatedInventors: David L. Tennent, Joseph M. Whalen
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Patent number: 6698247Abstract: A method for making silica includes delivering a silica precursor comprising a perfluorinated group to a conversion site and passing the silica precursor through a conversion flame to produce silica soot.Type: GrantFiled: May 4, 2001Date of Patent: March 2, 2004Assignee: Corning IncorporatedInventors: David L. Tennent, Joseph M. Whalen
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Publication number: 20030199065Abstract: Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm2 are achieved by: (1) applying a coating solution composed of a solvent and a non-ionic surfactant having a HLB number of less than 5 to the surface; and (2) drying the surface to remove the solvent and thereby bring the surfactant into direct contact with the hydrophobic polymer. The combination of a low HLB number and the drying step have been found to produce low binding surfaces which can withstand multiple washes with water and/or protein-containing solutions Alternatively, the low binding surfaces can be produced by applying the non-ionic surfactant to the mold surfaces which contact molten polymer and form the polymer into a desired shape, e.g., into a multi-well plate, a pipette tip, or the like. Further, the low binding surfaces may be produced by incorporating non-soluble, non-ionic surfactants having an HLB number of less than or equal to 10 into a polymer blend prior to molding the article.Type: ApplicationFiled: March 3, 2003Publication date: October 23, 2003Applicant: Corning IncorporatedInventors: Dana Craig Bookbinder, Edward John Fewkes, James Arthur Griffin, Frances M. Smith, David L. Tennent
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Patent number: 6565789Abstract: Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm2 are achieved by: (1) applying a coating solution composed of a solvent and a non-ionic surfactant having a HLB number of less than 5 to the surface; and (2) drying the surface to remove the solvent and thereby bring the surfactant into direct contact with the hydrophobic polymer. The combination of a low HLB number and the drying step have been found to produce low binding surfaces which can withstand multiple washes with water and/or protein-containing solutions. Alternatively, the low binding surfaces can be produced by applying the non-ionic surfactant to the mold surfaces which contact molten polymer and form the polymer into a desired shape, e.g., into a multi-well plate, a pipette tip, or the like. Further, the low binding surfaces may be produced by incorporating non-soluble, non-ionic surfactants having an HLB number of less than or equal to 10 into a polymer blend prior to molding the article.Type: GrantFiled: February 18, 2000Date of Patent: May 20, 2003Assignee: Corning IncorporatedInventors: Dana Craig Bookbinder, Edward John Fewkes, Jr., James Arthur Griffin, Frances M. Smith, David L. Tennent
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Publication number: 20030073067Abstract: Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm2 are achieved by: (1) applying a coating solution composed of a solvent and a non-ionic surfactant having a HLB number of less than 5 to the surface; and (2) drying the surface to remove the solvent and thereby bring the surfactant into direct contact with the hydrophobic polymer. The combination of a low HLB number and the drying step have been found to produce low binding surfaces which can withstand multiple washes with water and/or protein-containing solutions Alternatively, the low binding surfaces can be produced by applying the non-ionic surfactant to the mold surfaces which contact molten polymer and form the polymer into a desired shape, e.g., into a multi-well plate, a pipette tip, or the like. Further, the low binding surfaces may be produced by incorporating non-soluble, non-ionic surfactants having an HLB number of less than or equal to 10 into a polymer blend prior to molding the article.Type: ApplicationFiled: February 18, 2000Publication date: April 17, 2003Inventors: Dana Craig Bookfinder, Edward John Fewkes, James Arthur Griffin, Frances M. Smith, David L. Tennent
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Publication number: 20020162357Abstract: A method for making silica includes delivering a silica precursor comprising a perfluorinated group to a conversion site and passing the silica precursor through a conversion flame to produce silica soot.Type: ApplicationFiled: May 4, 2001Publication date: November 7, 2002Inventors: David L. Tennent, Joseph M. Whalen
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Publication number: 20020162359Abstract: A method for making silica includes delivering a silica precursor comprising a pseudohalogen to a conversion site and passing the silica precursor through a flame to produce silica soot.Type: ApplicationFiled: May 4, 2001Publication date: November 7, 2002Inventors: David L. Tennent, Joseph M. Whalen
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Patent number: 6379746Abstract: Methods for temporarily protecting a surface of a glass article by coating the surface are provided. The methods include forming a stable, hydrophobic, removable film on the surface at the end of the glass manufacturing process while the glass is still at an elevated temperature (e.g., above 175° C.). The film reduces chip adhesion to the surface as a result of cutting and grinding. After cutting and grinding, the film is removed allowing the glass to be used in such processes as the manufacture of liquid crystal displays (LCDs).Type: GrantFiled: January 31, 2000Date of Patent: April 30, 2002Assignee: Corning IncorporatedInventors: William Birch, Dana C. Bookbinder, Alain R. E. Carre, David L. Tennent
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Patent number: 6319664Abstract: Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm2 are achieved by: (1) applying to a hydrophobic polymer surface a coating solution composed of a solvent and a non-ionic surfactant having a HLB number of less than 5 and at least one hydrophilic element which can extend into an aqueous solution; and (2) drying the surface to remove the solvent and thereby bring the surfactant into direct contact with the hydrophobic polymer. The combination of a low HLB number and the drying step have been found to produce low binding surfaces which can withstand multiple washes with water and/or protein-containing solutions. Alternatively, the low binding surfaces can be produced by applying the non-ionic surfactant to mold surfaces which contact molten polymer and form the polymer into a desired shape, e.g., into a multi-well plate, a pipette tip, or the like.Type: GrantFiled: February 18, 2000Date of Patent: November 20, 2001Assignee: Corning IncorporatedInventors: Dana Craig Bookbinder, Edward John Fewkes, Jr., James Arthur Griffin, Frances M. Smith, David L. Tennent
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Patent number: 6233972Abstract: A method of providing a protective layer for a glass sheet. The protective layer provided by depositing a solution of a polymer and water on a glass sheet at a temperature high enough to provide a layer that is insoluble in water below a temperature of about 20° C. The layer is soluble in water at a temperature above about 60° C., so that the protective layer can be removed by rinsing in hot water.Type: GrantFiled: August 24, 1999Date of Patent: May 22, 2001Assignee: Corning IncorporatedInventors: Michelle R. Foster, David L. Tennent
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Patent number: 6093559Abstract: Hydrophobic polymer surfaces whose level of protein binding is less than about 50-80 ng/cm.sup.2 are achieved by: (1) applying to a hydrophobic polymer surface a coating solution composed of a solvent and a non-ionic surfactant having a HLB number of less than 5 and at least one hydrophilic element which can extend into an aqueous solution; and (2) drying the surface to remove the solvent and thereby bring the surfactant into direct contact with the hydrophobic polymer. The combination of a low HLB number and the drying step have been found to produce low binding surfaces which can withstand multiple washes with water and/or protein-containing solutions. Alternatively, the low binding surfaces can be produced by applying the non-ionic surfactant to mold surfaces which contact molten polymer and form the polymer into a desired shape, e.g., into a multi-well plate, a pipette tip, or the like.Type: GrantFiled: August 26, 1997Date of Patent: July 25, 2000Assignee: Corning IncorporatedInventors: Dana Craig Bookbinder, Edward John Fewkes, Jr., James Arthur Griffin, Frances M. Smith, David L. Tennent
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Patent number: 4892857Abstract: An apparatus for use in liquid-phase, gas-phase and mixed-phase reactions is disclosed for providing an efficient flow-through design within which results a low pressure drop. The apparatus may be used as a catalyst or electrocatalyst and consists essentially of a ceramic substrate having thin walls with open porosity wherein said walls define a plurality of cells extending substantially longitudinally parallel through-and-through the substrate. The substrate includes an electrically conductive layer, having a resistivity of no greater than about 100 ohm-cm. The apparatus exhibits an improved structural geometry and provides greater meniscus control.Type: GrantFiled: May 20, 1987Date of Patent: January 9, 1990Assignee: Corning IncorporatedInventors: David L. Tennent, Gerald D. Fong, Christine L. Hoaglin
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Patent number: 4522924Abstract: The present invention relates to an immobilized enzyme composite having a mica carrier. More particularly, the composite comprises a mixture of an enzyme and a water-swelling mica selected from fluorohectorite, boron fluorophlogopite, hydroxyl boron phlogopite and solid solutions of at least one mica and a structurally compatible species selected from talc, fluorotalc, polylithonite, fluoropolylithonite, phlogopite, and fluorophlogopite.Type: GrantFiled: March 29, 1984Date of Patent: June 11, 1985Assignee: Corning Glass WorksInventors: David L. Tennent, Bhavender P. Sharma