Abstract: The present invention relates to a nasogastric formulation comprising an amino acid source, a carbohydrate source, a lipid source, and a fatty acid delivery agent wherein the fatty acid has a bond hydrolysable in the colon to deliver free fatty acids such as short chain fatty acid acetate without having an adverse affect on the capacity to pass through a tube for tube feeding.

Abstract: Delivery to the colon of fatty acids especially Short Chain Fatty Acids (SCFA) can be effected by covalently linking SCFA to a carrier that is preferably a form of carbohydrate, by an ester link. The SCFA is protected by its link with the carbohydrate through the small intestine, and where the carbohydrate is digestible in the small intestine such as a digestible starch, the starch can also be protected from digestion in the small intestine by the substitution. Levels of SCFA such as acetate, propionate and butyrate may be elevated to have beneficial effects in the prevention of colonic disorders such as rectal cancer, diverticulities, colitis, diarrhea and constipation.