Patents by Inventor David Lai

David Lai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11971878
    Abstract: Systems and methods for supporting both batch processing and streaming data applications, to load and process data incrementally, while providing a near-constantly materialized dataset based on raw blockchain data, are described. For example, the system may receive first on-chain data in a first format via a first input stream, wherein the first on-chain data originates from a blockchain node of a blockchain network. The system may transform the first on-chain data to a second format for storage in a second dataset, wherein the second format comprises an unbounded table.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: April 30, 2024
    Assignee: Coinbase, Inc.
    Inventors: Jie Zhang, Zhicong Liang, Yaohua Yang, David Lai, Chaoqing Lu, Jinghan Xu, Xu Meng
  • Publication number: 20240115781
    Abstract: Systems and apparatuses for blood oxygenation are disclosed. A system includes a first layer defining a plurality of banks of first channels each extending in a first direction. The plurality of banks of first channels are configured to receive blood via a trunk channel. The system includes a second layer defining a bank of second channels extending in a second direction. The bank of second channels are configured to receive oxygen. The first direction is different from the second direction. The system includes a membrane disposed between the first layer and the second layer and configured to cause the oxygen to permeate from the second layer to the first layer to oxygenate the blood.
    Type: Application
    Filed: October 3, 2023
    Publication date: April 11, 2024
    Applicant: The Charles Stark Draper Laboratory, Inc.
    Inventors: Brett Isenberg, Else Vedula, David Sutherland, Diana Lewis, Jose Santos, WeiXuan Lai, Ernie Kim, Beau Landis, Jeffrey Borenstein, Bryan Teece, Samuel Blumenstiel, Joseph Urban
  • Patent number: 11954114
    Abstract: Systems and methods for a unified approach that is compatible with all blockchains, protocols, etc. The systems and methods use a bifurcated indexing system with a dynamically selected application service. The systems and methods bifurcate the indexing process into a storage layer and a compute layer.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: April 9, 2024
    Assignee: Coinbase, Inc.
    Inventors: Jie Zhang, Zhicong Liang, Yaohua Yang, David Lai, Chaoqing Lu, Jinghan Xu, Xu Meng
  • Patent number: 11939361
    Abstract: The present invention relates to compositions of peptide inhibitors of the interleukin-23 receptor (IL-23R) or pharmaceutically acceptable salt or solvate forms thereof, corresponding pharmaceutical compositions, methods and/or uses for treatment of autoimmune inflammation and related diseases and disorders.
    Type: Grant
    Filed: November 19, 2021
    Date of Patent: March 26, 2024
    Assignees: Janssen Pharmaceutica NV, Protagonist Therapeutics, Inc.
    Inventors: Giustino Di Pretoro, Dajun Sun, Gopal Rajan, Geraldine Broeckx, Nathalie Mertens, Shu Li, Felix Lai, Mohammad Masjedizadeh, Anne M. Fourie, Beverly Knight, David Polidori, Santhosh Francis Neelamkavil, Nishit Modi, Ashok Bhandari, Xiaoli Cheng
  • Publication number: 20240096387
    Abstract: A memory device comprising a programmable command-and-address (CA) interface and/or a programmable data interface is described. In an operational mode, two or more CA interfaces may be active. In another operational mode, at least one, but not all, CA interfaces may be active. In an operational mode, all of the data interfaces may be active. In another operational mode, at least one, but not all, data interfaces may be active. The memory device can include circuitry to select: an operational mode; a sub-mode within an operational mode; one or more CA interfaces as the active CA interface(s); a main CA interface from multiple active CA interfaces; and/or one or more data interfaces as the active data interfaces. The circuitry may perform these selection(s) based on one or more bits in one or more registers and/or one or more signals received on one or more pins.
    Type: Application
    Filed: September 1, 2023
    Publication date: March 21, 2024
    Applicant: Rambus Inc.
    Inventors: Ian Shaeffer, Lawrence Lai, Fan Ho, David A. Secker, Wayne S. Richardson, Akash Bansal, Brian S. Leibowitz, Kyung Suk Oh
  • Publication number: 20240093512
    Abstract: Provided are photo-curable foam-forming compositions, methods of making and using them, and a dispenser for injecting the foam-forming composition for the insulation of buildings. In one aspect, the present disclosure provides for a method of insulating a surface, such as that of a building cavity with an insulating foam, the method comprising: irradiating a foam-forming composition with light, the foam-forming composition comprising: a polymerizable component (e.g., based on epoxy or acrylate); an effective amount of a photoinitiator; and a blowing agent; and injecting the irradiated foam-forming composition adjacent the surface.
    Type: Application
    Filed: December 7, 2021
    Publication date: March 21, 2024
    Inventors: Ying Wang, Choung-Houng Lai, Nicholas David Orf, Rachel Brown, Nicky Chan
  • Patent number: 11929153
    Abstract: A process for converting a first hydrocarbon feed stream to one or more liquid transportation fuels in a petroleum refinery where the feed stream is analyzed by at least one analytical method to produce data that is transformed to wavelet coefficients data. A pattern recognition algorithm is trained to recognize subtle features in the wavelet coefficients data that are associated with an attribute of the feed stream. The trained pattern recognition algorithm then rapidly classifies potential hydrocarbon feed streams as a member of either a first group or a second group where the second group comprises hydrocarbon feed streams where the attribute or chemical characteristic at or above a predetermined threshold value. This classification allows rapid decisions to be made regarding utilization of the feedstock in the refinery that may include altering at least one variable in the operation of the refinery.
    Type: Grant
    Filed: December 13, 2022
    Date of Patent: March 12, 2024
    Assignee: Phillips 66 Company
    Inventors: Ayuba Fasasi, Alec C. Durrell, Jinfeng Lai, David A. Henning, Franklin Uba
  • Patent number: 11914560
    Abstract: Systems and methods for creating a reorganization-immune blockchain index using mono-increasing sequence records are described. For example, the system may receive on-chain data for a plurality of blocks, wherein the plurality of blocks comprises a first block comprising a first event of a plurality of blockchain events within the on-chain data. The system may determine a first sequence number for the first event, wherein the first sequence number is based on a mono-increasing sequence record.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: February 27, 2024
    Assignee: Coinbase, Inc.
    Inventors: Jie Zhang, Zhicong Liang, Yaohua Yang, David Lai, Chaoqing Lu, Jinghan Xu, Xu Meng
  • Publication number: 20240007525
    Abstract: Systems and methods for a unified approach that is compatible with all blockchains, protocols, etc. The systems and methods use a bifurcated indexing system with a dynamically selected application service. The systems and methods bifurcate the indexing process into a storage layer and a compute layer.
    Type: Application
    Filed: June 30, 2022
    Publication date: January 4, 2024
    Applicant: Coinbase, Inc.
    Inventors: Jie ZHANG, Zhicong LIANG, Yaohua YANG, David LAI, Chaoqing LU, Jinghan XU, Xu MENG
  • Publication number: 20240004851
    Abstract: Systems and methods for creating a reorganization-immune blockchain index using mono-increasing sequence records are described. For example, the system may receive on-chain data for a plurality of blocks, wherein the plurality of blocks comprises a first block comprising a first event of a plurality of blockchain events within the on-chain data. The system may determine a first sequence number for the first event, wherein the first sequence number is based on a mono-increasing sequence record.
    Type: Application
    Filed: June 30, 2022
    Publication date: January 4, 2024
    Applicant: Coinbase, Inc.
    Inventors: Jie ZHANG, Zhicong LIANG, Yaohua YANG, David LAI, Chaoqing LU, Jinghan XU, Xu MENG
  • Publication number: 20240004894
    Abstract: Systems and methods for a unified approach that is compatible with all blockchains, protocols, etc. The systems and methods use a bifurcated indexing system with a dynamically selected application service. The systems and methods bifurcate the indexing process into a storage layer and a compute layer.
    Type: Application
    Filed: June 30, 2022
    Publication date: January 4, 2024
    Applicant: Coinbase, Inc.
    Inventors: Jie ZHANG, Zhicong LIANG, Yaohua YANG, David LAI, Chaoqing LU, Jinghan XU, Xu MENG
  • Publication number: 20240004866
    Abstract: Systems and methods for supporting both batch processing and streaming data applications, to load and process data incrementally, while providing a near-constantly materialized dataset based on raw blockchain data, are described. For example, the system may receive first on-chain data in a first format via a first input stream, wherein the first on-chain data originates from a blockchain node of a blockchain network. The system may transform the first on-chain data to a second format for storage in a second dataset, wherein the second format comprises an unbounded table.
    Type: Application
    Filed: June 30, 2022
    Publication date: January 4, 2024
    Applicant: Coinbase, Inc.
    Inventors: Jie ZHANG, Zhicong LIANG, Yaohua YANG, David LAI, Chaoqing LU, Jinghan XU, Xu MENG
  • Patent number: 11666874
    Abstract: The invention comprises a novel modular, generalizable meso-micro-nano-fluidic platform apparatus, design and methodology which in exemplary embodiments may be applied in conjunction with a novel external triggering and automation/feedback loop control mechanism deployed via computer to explore the phase space of single or double emulsification for applications including the encapsulation of hydrophilic active pharmacological ingredients (APIs). End use applications include the mass production of particulate encapsulation of hydrophobic or hydrophilic APIs with automatic or user-supervised feedback methodology to control and discover mass production or per-drug customized settings of interest for the manufacture of novel or extant therapeutics.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: June 6, 2023
    Assignees: Glaxosmithkline Intellectual Property Deveelopment Limited, Massachusetts Institute of Technology
    Inventors: David Lai, Filippos Touriomousis, Andreas Mershin, Neil Gershenfeld
  • Publication number: 20220311257
    Abstract: A battery system of an electric vehicle includes a plurality of battery packs. Each battery pack includes a plurality of battery cells enclosed within a housing. A battery management device is electrically connected to each of the battery packs and configured to control an electrical output of the plurality of battery packs.
    Type: Application
    Filed: June 15, 2022
    Publication date: September 29, 2022
    Applicant: Proterra Operating Company, Inc.
    Inventors: David LAI, Dustin GRACE, Derek R. PAUL, Yale CHEN, Cagkan YILDZ
  • Publication number: 20220219504
    Abstract: A temperature control system for an electric vehicle includes a cabin temperature control system configured to control flow of a refrigerant through one or more heat exchangers to control a temperature of a cabin of the electric vehicle, a battery temperature control system configured to control the flow of a coolant through one or more heat exchangers to control a temperature of a battery system of the electric vehicle, and a power electronics temperature control system configured to control the flow of coolant through one or more heat exchangers to control a temperature of one or more power electronics. In a first configuration of the temperature control system, the battery temperature control system and the power electronics temperature control system may be thermally isolated, and, in a second configuration, the battery temperature control system and the power electronics temperature control system may thermally interact.
    Type: Application
    Filed: November 29, 2021
    Publication date: July 14, 2022
    Applicant: Proterra Operating Company, Inc.
    Inventors: James HARPER, Kevin MYERS, David LAI
  • Patent number: 11214115
    Abstract: A temperature control system for an electric vehicle includes a cabin temperature control system configured to control flow of a refrigerant through one or more heat exchangers to control a temperature of a cabin of the electric vehicle, a battery temperature control system configured to control the flow of a coolant through one or more heat exchangers to control a temperature of a battery system of the electric vehicle, and a power electronics temperature control system configured to control the flow of coolant through one or more heat exchangers to control a temperature of one or more power electronics. In a first configuration of the temperature control system, the battery temperature control system and the power electronics temperature control system may be thermally isolated, and, in a second configuration, the battery temperature control system and the power electronics temperature control system may thermally interact.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: January 4, 2022
    Assignee: PROTERRA INC.
    Inventors: James Harper, Kevin Myers, David Lai
  • Patent number: 11166453
    Abstract: Provided herein is technology relating to cryopreservation and particularly, but not exclusively, to devices, systems, and methods for cryopreservation of biological materials such as oocytes, zygotes, and embryos. In particular, provided herein are methods of using microfluidic devices to exposing biological material to a vitrification solution having a time dependent concentration of a cryoprotectant agent.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: November 9, 2021
    Assignee: The Regents of the University of Michigan
    Inventors: David Lai, Shuichi Takayama, Gary D. Smith, Jun Ding
  • Patent number: 10898708
    Abstract: Systems and methods for applying a pulsed electromagnetic fields. A system for applying a pulsed electromagnetic field (PEMF) to a cell, comprising: a sensor for obtaining a characteristic of the cell; a memory module having stored therein a plurality of characteristics and PEMF efficacy window data, each characteristic having its corresponding PEMF efficacy window data; a pulse generator coupled to a set of PEMF coils and configured to generate an output of electrical pulses to drive the set of PEMF coils; and a controller in communication with the sensor, the memory module and the pulse generator, wherein the controller is configured to: retrieve, from the memory module, the PEMF efficacy window data that corresponds to the characteristic of the cell obtained by the sensor; and control the output of the pulse generator based on the retrieved PEMF efficacy window data such that the set of PEMF coils apply a PEMF in accordance with the PEMF efficacy window data.
    Type: Grant
    Filed: May 5, 2016
    Date of Patent: January 26, 2021
    Assignees: National University of Singapore, ETH Zurich
    Inventors: Alfredo Franco-Obregon, Chuen Neng Lee, Wee Chuan Melvin Loh, Jürg Hans Fröhlich, Christian Beyer, Tien Min David Lai
  • Publication number: 20200376920
    Abstract: A temperature control system for an electric vehicle includes a cabin temperature control system configured to control flow of a refrigerant through one or more heat exchangers to control a temperature of a cabin of the electric vehicle, a battery temperature control system configured to control the flow of a coolant through one or more heat exchangers to control a temperature of a battery system of the electric vehicle, and a power electronics temperature control system configured to control the flow of coolant through one or more heat exchangers to control a temperature of one or more power electronics. In a first configuration of the temperature control system, the battery temperature control system and the power electronics temperature control system may be thermally isolated, and, in a second configuration, the battery temperature control system and the power electronics temperature control system may thermally interact.
    Type: Application
    Filed: June 3, 2019
    Publication date: December 3, 2020
    Applicant: Proterra Inc.
    Inventors: James HARPER, Kevin MYERS, David LAI
  • Patent number: D1017465
    Type: Grant
    Filed: September 20, 2021
    Date of Patent: March 12, 2024
    Assignee: Ford Global Technologies, LLC
    Inventors: Max Wolff, Maurizio Tocco, David Dewitt, Andrew Wolton, Nonthawat Kongsari, Siddhartha Kazami, Rohan Satyamurthy, Emily Lai, Luana Teixeira, Peter Jones