Abstract: Users of Internet messaging services that are initially identified using separate identifiers that may be associated with respective service providers (e.g., email addresses) can manage network identities using a single unified set of account information managed by a registry service. When a second user wishes to communicate with a first user, the second user provides any service provider identity that is believed to be associated with the first user to determine if the specified service provider identity appears to match the intended subscriber. If so, the second user may specify a nickname (unique to the second subscriber but not necessarily globally unique) to be associated internally within the registry with the internal unique identifier of the first subscriber as part of the second subscriber's user record.

Abstract: Users of Internet services (e.g., SKYPE messaging service, GOOGLETALK messaging service, AOL INSTANT MESSENGER messaging service, and MICROSOFT MESSENGER messaging service) that are initially identified using separate identifiers that may be associated with respective service providers (e.g., email addresses) can manage network identities using a single unified set of account information managed by a registry service. The registry authenticates the user's request(s) to bind a service provider identity to his or her personal registry user record. The registry internally associates the service provider identity to an internal unique identifier that is not exposed to subscribers. When a second user wishes to communicate with a first user, the second user provides any service provider identity that is believed to be associated with the first user to determine if the specified service provider identity appears to match the intended subscriber.

Abstract: During normal operation, a user terminal supported by an IP-PBX server establishes a call by resolving the name of the IP-PBX server using a DNS server. When the DNS server provides the address of the IP-PBX server, the IP-PBX server can be contacted. However, if the SIP controller learns that the IP-PBX is no longer operating, the information stored by the service provider environment may be used to build or configure an IP-Centrex server at a remote site which takes over for the failing IP-PBX server. The newly configured IP-Centrex server then registers itself with the SIP controller and either the SIP controller or the IP-Centrex server then informs the DNS server of the IP address of the IP-Centrex and tells the DNS server that the IP-Centrex server will respond to messages for the failed IP-PBX server. The newly configured IP-Centrex server then handles the messages and control flow previously handled by the IP-PBX server.

Abstract: During normal operation, a user terminal supported by an IP-PBX server establishes a call by resolving the name of the IP-PBX server using a DNS server. When the DNS server provides the address of the IP-PBX server, the IP-PBX server can be contacted. However, if the SIP controller learns that the IP-PBX is no longer operating, the information stored by the service provider environment may be used to build or configure an IP-Centrex server at a remote site which takes over for the failing IP-PBX server. The newly configured IP-Centrex server then registers itself with the SIP controller and either the SIP controller or the IP-Centrex server then informs the DNS server of the IP address of the IP-Centrex and tells the DNS server that the IP-Centrex server will respond to messages for the failed IP-PBX server. The newly configured IP-Centrex server then handles the messages and control flow previously handled by the IP-PBX server.

Abstract: A target asparagine residue of HIF 1 alpha and 2 alpha is hydroxylated at high oxygen tension to render HIF as a weak transcription factor. An asparagine hydroxylase hydroxylation motif and binding motif is proposed. A method of screening for agonists or antagonists of an asparagine hydroxylase is also proposed and involves mixing peptides or proteins having the hydroxylation and or the binding motif with asparagine hydroxylase and a candidate agonist or antagonist. The extent of inhibition or enhancement of binding; level of asparagine hydroxylation or transactivation may be measured depending on the nature of the protein or peptide. Additionally altered proteins resistant to hydroxylation are described as are nucleic acids encoding such proteins.

Abstract: Users of Internet services (e.g., SKYPE messaging service, GOOGLETALK messaging service, AOL INSTANT MESSENGER messaging service, and MICROSOFT MESSENGER messaging service) that are initially identified using separate identifiers that may be associated with respective service providers (e.g., email addresses) can manage network identities using a single unified set of account information managed by a registry service. The registry authenticates the user's request(s) to bind a service provider identity to his or her personal registry user record. The registry internally associates the service provider identity to an internal unique identifier that is not exposed to subscribers. When a second user wishes to communicate with a first user, the second user provides any service provider identity that is believed to be associated with the first user to determine if the specified service provider identity appears to match the intended subscriber.

Abstract: A target asparagine residue of HIF 1 alpha and 2 alpha is hydroxylated at high oxygen tension to render HIF as a weak transcription factor. An asparagine hydroxylase hydroxylation motif and binding motif is proposed. A method of screening for agonists or antagonists of an asparagine hydroxylase is also proposed and involves mixing peptides or proteins having the hydroxylation and or the binding motif with asparagine hydroxylase and a candidate agonist or antagonist. The extent of inhibition or enhancement of binding; level of asparagine hydroxylation or transactivation may be measured depending on the nature of the protein or peptide. Additionally altered proteins resistant to hydroxylation are described as are nucleic acids encoding such proteins.