Abstract: Disclosed herein are designed heterodimer proteins, monomeric polypeptides capable of forming heterodimer proteins, protein scaffolds including such polypeptides, and methods for using the heterodimer proteins and subunit polypeptides for designing logic gates.

Abstract: A control system for an engine includes a distributed control module configured to be associated with a sensor of the engine, a digital link, and a communication control. The distributed control module is connected to the communication control via the digital link. The communication control includes a bus communication engine configured to communicate with the engine control via a bus, and a memory. The memory includes a first buffer that is associated with the distributed control module and a second buffer that is associated with the bus communication engine.

Abstract: A reflector assembly configured to move between a stowed configuration and a deployed configuration includes a central hub, a series of ribs coupled to the central hub, and a flexible reflective material attached to the ribs. Each rib includes a root rib, an intermediate rib, and a tip rib. The root rib is configured to rotate in a first direction about a first axis away from a coaxial axis of the central hub, the intermediate rib is configured to rotate in the first direction about a second axis substantially parallel to the first axis, and the tip rib is configured to rotate in the first direction about a third axis substantially parallel to the second axis as the reflector assembly moves into the deployed configuration. The flexible reflective material and the ribs together form a reflective surface with a substantially paraboloidal surface profile configured to focus electromagnetic energy.

Abstract: A reflector assembly configured to move between a stowed configuration and a deployed configuration includes a central hub, a series of ribs coupled to the central hub, and a flexible reflective material attached to the ribs. Each rib includes a root rib, an intermediate rib, and a tip rib. The root rib is configured to rotate in a first direction about a first axis away from a coaxial axis of the central hub, the intermediate rib is configured to rotate in the first direction about a second axis substantially parallel to the first axis, and the tip rib is configured to rotate in the first direction about a third axis substantially parallel to the second axis as the reflector assembly moves into the deployed configuration. The flexible reflective material and the ribs together form a reflective surface with a substantially paraboloidal surface profile configured to focus electromagnetic energy.

Abstract: A CT system includes a rotatable gantry having an opening for receiving an object to be scanned and an x-ray source coupled to the gantry and configured to project x-rays through the opening. The x-ray source includes a target, a first cathode configured to emit a first beam of electrons toward the target, a first gridding electrode coupled to the first cathode, a second cathode configured to emit a second beam of electrons toward the target, and a second gridding electrode coupled to the second cathode. The system includes a generator configured to energize the first cathode to a first kVp and to energize the second cathode to a second kVp, and a detector attached to the gantry and positioned to receive x-rays that pass through the opening.

Abstract: A plurality of projection images are acquired over an angular range during the slow rotation of a C-arm gantry having a source and detector. Phase-specific reconstructions are generated from the plurality of projections, wherein each phase-specific reconstruction is generated generally from projections acquired at or near the respective phase. In one embodiment, a plurality of motion estimates are generated based upon the phase-specific reconstructions. One or more motion-corrected reconstructions may be generated using the respective motion estimates and projections. The motion-corrected reconstructions may be associated to form motion-corrected volume renderings.

Abstract: A CT system includes a rotatable gantry having an opening for receiving an object to be scanned and an x-ray source coupled to the gantry and configured to project x-rays through the opening. The x-ray source includes a target, a first cathode configured to emit a first beam of electrons toward the target, a first gridding electrode coupled to the first cathode, a second cathode configured to emit a second beam of electrons toward the target, and a second gridding electrode coupled to the second cathode. The system includes a generator configured to energize the first cathode to a first kVp and to energize the second cathode to a second kVp, and a detector attached to the gantry and positioned to receive x-rays that pass through the opening.

Abstract: An X-ray imaging system is provided. The X-ray imaging system includes a distributed X-ray source and a detector. The distributed X-ray source is configured to emit X-rays from a plurality of emission points arranged as a substantially linear segment, a substantially arcuate segment, a curvilinear segment, or a substantially non-planar surface and the detector is configured to generate a plurality of signals in response to X-rays incident upon the detector.

Abstract: A method, system and computer readable medium for implementing and performing a multi-resolution contrast-based dynamic range management algorithm and allowing for the efficient compression of an intensity dynamic range of an input image to a reduced intensity dynamic range of an image display signal. Specifically, the method, system and computer readable medium of the invention comprise decomposing the input image into a plurality of image components, modifying the intensity characteristics of the plurality of image components and reconstructing the plurality of image components into an output image for display on an image display device. In another aspect of the method, system and computer readable medium of the invention, the decomposition of the input image and reconstruction into an output image are performed using a Laplacian pyramid.

Abstract: A plurality of projection images are acquired over an angular range during the slow rotation of a C-arm gantry having a source and detector. Phase-specific reconstructions are generated from the plurality of projections, wherein each phase-specific reconstruction is generated generally from projections acquired at or near the respective phase. In one embodiment, a plurality of motion estimates are generated based upon the phase-specific reconstructions. One or more motion-corrected reconstructions may be generated using the respective motion estimates and projections. The motion-corrected reconstructions may be associated to form motion-corrected volume renderings.

Abstract: A technique is provided for generating a three-dimensional image from fluoroscopic projection images. The technique allows for the acquisition of fluoroscopic images at different perspectives relative to a region of interest. One or more three-dimensional images may then be reconstructed from the fluoroscopic projection images. The three-dimensional images may then be displayed to provide anatomic context for the fluoroscopic application. A fluoroscopic projection image, such as the most current fluoroscopic image, may be superimposed on the three-dimensional image if desired.

Abstract: Some configurations of the present invention provide a method for locating a low contrast movable object coupled mechanically to a marker object in a series of image frames that include images of the low contrast object and the marker object. The method includes locating the marker object in a first selected frame of the series of image frames, selecting a patch of the first selected frame as a template of the marker object, and utilizing the template of the marker object to estimate a location of the marker object in a second selected frame of the series of image frames. The second selected frame is registered with the first selected frame utilizing the estimated location of the marker object in the second selected frame. The registered first selected frame and the second selected frame are fused to thereby enhance the contrast of the low contrast moveable object.

Abstract: A method, system and computer readable medium for implementing and performing a multi-resolution contrast-based dynamic range management algorithm and allowing for the efficient compression of an intensity dynamic range of an input image to a reduced intensity dynamic range of an image display signal. Specifically, the method, system and computer readable medium of the invention comprise decomposing the input image into a plurality of image components, modifying the intensity characteristics of the plurality of image components and reconstructing the plurality of image components into an output image for display on an image display device. In another aspect of the method, system and computer readable medium of the invention, the decomposition of the input image and reconstruction into an output image are performed using a Laplacian pyramid.

Abstract: A method for detecting or sensing zero crossings in a rectified power signal comprising three separate signal constituents for energizing a three-phase circuit is provided. The method includes the steps of sampling at least two consecutive cycles of each signal constituent at a predetermined sampling rate; storing a predetermined number of samples for each signal constituent; computing a respective initial zero crossing estimate for each signal constituent; and checking the accuracy of the respective initial zero crossing estimate for each signal constituent of the power signal. If necessary, the method can further include the step of adjusting the initial estimate for the zero crossing of at least one of the three signal constituents of the power signal. In each case, the detected or sensed zero crossings, in turn, enable detection of a ground fault in the three phase circuit.