Patents by Inventor David Lawrence Newsom

David Lawrence Newsom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPREHENSIVE ANALYSIS PIPELINE FOR DISCOVERY OF HUMAN GENETIC VARIATION
    Publication number: 20170220732
    Abstract: Systems and methods for analyzing genetic sequence data involve: (a) obtaining, by a computer system, genetic sequencing data pertaining to a subject; (b) splitting the genetic sequencing data into a plurality of segments; (c) processing the genetic sequencing data such that intra-segment reads, read pairs with both mates mapped to the same data set, are saved to a respective plurality of individual binary alignment map (BAM) files corresponding to that respective segment; (d) processing the genetic sequencing data such that inter-segment reads, read pairs with both mates mapped to different segments, are saved into at least a second BAM file; and (e) processing at least the first plurality of BAM files along parallel processing paths. The plurality of segments may correspond to any given number of genomic subregions and may be selected based upon the number of processing cores used in the parallel processing.
    Type: Application
    Filed: January 23, 2017
    Publication date: August 3, 2017
    Inventors: Peter WHITE, David Lawrence NEWSOM, Yangyiu HU
  • Comprehensive analysis pipeline for discovery of human genetic variation
    Patent number: 9552458
    Abstract: Systems and methods for analyzing genetic sequence data involve: (a) obtaining, by a computer system, genetic sequencing data pertaining to a subject; (b) splitting the genetic sequencing data into a plurality of segments; (c) processing the genetic sequencing data such that intra-segment reads, read pairs with both mates mapped to the same data set, are saved to a respective plurality of individual binary alignment map (BAM) files corresponding to that respective segment; (d) processing the genetic sequencing data such that inter-segment reads, read pairs with both mates mapped to different segments, are saved into at least a second BAM file; and (e) processing at least the first plurality of BAM files along parallel processing paths. The plurality of segments may correspond to any given number of genomic subregions and may be selected based upon the number of processing cores used in the parallel processing.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: January 24, 2017
    Assignee: THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL
    Inventors: Peter White, David Lawrence Newsom, Yangqiu Hu
  • Comprehensive Analysis Pipeline for Discovery of Human Genetic Variation
    Publication number: 20130311106
    Abstract: Systems and methods for analyzing genetic sequence data involve: (a) obtaining, by a computer system, genetic sequencing data pertaining to a subject; (b) splitting the genetic sequencing data into a plurality of segments; (c) processing the genetic sequencing data such that intra-segment reads, read pairs with both mates mapped to the same data set, are saved to a respective plurality of individual binary alignment map (BAM) files corresponding to that respective segment; (d) processing the genetic sequencing data such that inter-segment reads, read pairs with both mates mapped to different segments, are saved into at least a second BAM file; and (e) processing at least the first plurality of BAM files along parallel processing paths. The plurality of segments may correspond to any given number of genomic subregions and may be selected based upon the number of processing cores used in the parallel processing.
    Type: Application
    Filed: March 15, 2013
    Publication date: November 21, 2013
    Applicant: The Research Institute at Nationwide Children's Hospital
    Inventors: Peter White, David Lawrence Newsom, Yangqiu Hu