Patents by Inventor David Lazarus
David Lazarus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260053957Abstract: The present invention generally relates to the field of ultrasound contrast-agents (USCA). In particular, it relates to a freeze-dried composition comprising an amphiphilic lipid compound comprising a phospholipid, a fluorinated compound in liquid form and a freeze-drying protecting component which may be reconstituted for preparing a suspension of nanodroplets useful in diagnostic or therapeutic applications. It further relates to the method for the preparation of such freeze-dried composition.Type: ApplicationFiled: August 11, 2023Publication date: February 26, 2026Applicant: Bracco Suisse SAInventors: Romain MELICH, Charles BERGER, David LAZARUS, Philippe BUSSAT, Samir CHERKAOUI
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Publication number: 20260029400Abstract: Formulations of gas-filled microvesicles comprising a ligand, which may advantageously be used in methods for separating cells or biological materials. The formulations comprise a phospholipid and a suitable mixture of a pegylated phospholipid and of a pegylated phospholipid comprising a ligand.Type: ApplicationFiled: September 27, 2025Publication date: January 29, 2026Applicant: Bracco Suisse SAInventors: Philippe Bussat, Samir CHERKAOUI, David LAZARUS
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Patent number: 12449418Abstract: Formulations of gas-filled microvesicles comprising a ligand, which may advantageously be used in methods for separating cells or biological materials. The formulations comprise a phospholipid and a suitable mixture of a pegylated phospholipid and of a pegylated phospholipid comprising a ligand.Type: GrantFiled: December 19, 2019Date of Patent: October 21, 2025Assignee: Bracco Suisse SAInventors: Philippe Bussat, Samir Cherkaoui, David Lazarus
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Publication number: 20250057992Abstract: Method for the preparation of an aqueous suspension of calibrated nanodroplets with a core comprising a low boiling fluorinated compound through microfluidic technology.Type: ApplicationFiled: December 21, 2022Publication date: February 20, 2025Applicant: Bracco Suisse SAInventors: Romain MELICH, Philippe BUSSAT, David LAZARUS, Samir CHERKAOUI
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Patent number: 11717570Abstract: Lipid formulation particularly for preparing stable gas-filled microvesicles, comprising distearoyl-phosphatidylcholine (DSPC), dipalmitoylphosphatidylethanolamine-PEG5000 (DPPE-PEG5000) and palmitic acid in an advantageous relative molar ratio. The formulation is useful in particular for therapeutic application with ultrasounds.Type: GrantFiled: May 14, 2020Date of Patent: August 8, 2023Assignee: Bracco Suisse SAInventors: Philippe Bussat, Samir Cherkaoui, David Lazarus, Eric Allémann, Michel Schneider, Christian Guillot
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Publication number: 20220211850Abstract: Lipid formulation particularly for preparing stable gas-filled microvesicles, comprising distearoyl-phosphatidylcholine (DSPC), dipalmitoylphosphatidylethanolamine-PEG5000 (DPPE-PEG5000) and palmitic acid in an advantageous relative molar ratio. The formulation is useful in particular for therapeutic application with ultrasounds.Type: ApplicationFiled: May 14, 2020Publication date: July 7, 2022Applicant: Bracco Suisse SAInventors: Philippe Bussat, Samir CHERKAOUI, David LAZARUS, Eric ALLÉMANN, Michel SCHNEIDER, Christian GUILLOT
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Publication number: 20210389320Abstract: Formulations of gas-filled microvesicles comprising a ligand, which may advantageously be used in methods for separating cells or biological materials. The formulations comprise a phospholipid and a suitable mixture of a pegylated phospholipid and of a pegylated phospholipid comprising a ligand.Type: ApplicationFiled: December 19, 2019Publication date: December 16, 2021Applicant: Bracco Suisse SAInventors: Philippe BUSSAT, Samir CHERKAOUI, David LAZARUS
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Patent number: 9247422Abstract: In a method of communicating content over a wireless communication link between a base station set-top (BSS) and one or more hosts, where each of the one or more hosts have an interface protocol substantially complying with at least a subset of a copy protection standard, an encrypted signal is at least one of received and stored in the BSS, and the encrypted signal is turned into an encrypted data packet stream. The BSS wirelessly transmits the data packet stream to one or more wireless interface apparatuses (WIAs) which are interfaced with at least one host through the interface protocol. In addition, the WIA forwards the encrypted data packet stream to the one or more hosts through implementation of the interface protocol.Type: GrantFiled: November 30, 2007Date of Patent: January 26, 2016Assignee: Google Technology Holdings LLCInventors: David Lazarus, Deven Vazirani
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Publication number: 20130101520Abstract: The invention is directed to injectable suspensions of gas-filled microvesicles, as well as methods of preparing and using the same, especially as ultrasound contrast agents.Type: ApplicationFiled: September 12, 2012Publication date: April 25, 2013Applicant: Bracco Suisse S.A.Inventors: Michel SCHNEIDER, Feng Yan, David Lazarus, Jean Brochot, Jerome Puginier
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Publication number: 20120093732Abstract: The invention is directed to injectable suspensions of gas-filled microvesicles, as well as methods of preparing and using the same, especially as ultrasound contrast agents.Type: ApplicationFiled: September 1, 2011Publication date: April 19, 2012Applicant: Bracco Suisse S.A.Inventors: Michel Schneider, Feng Yan, David Lazarus, Jean Brochot, Jerome Puginier
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Publication number: 20090141897Abstract: In a method of communicating content over a wireless communication link between a base station set-top (BSS) and one or more hosts, where each of the one or more hosts have an interface protocol substantially complying with at least a subset of a copy protection standard, an encrypted signal is at least one of received and stored in the BSS, and the encrypted signal is turned into an encrypted data packet stream. The BSS wirelessly transmits the data packet stream to one or more wireless interface apparatuses (WIAs) which are interfaced with at least one host through the interface protocol. In addition, the WIA forwards the encrypted data packet stream to the one or more hosts through implementation of the interface protocol.Type: ApplicationFiled: November 30, 2007Publication date: June 4, 2009Applicant: GENERAL INSTRUMENT CORPORATIONInventors: David Lazarus, Deven Vazirani
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Publication number: 20080063603Abstract: The invention is directed to injectable suspensions of gas-filled microvesicles, as well as methods of preparing and using the same, especially as ultrasound contrast agents.Type: ApplicationFiled: September 7, 2007Publication date: March 13, 2008Applicant: Bracco International B.V.Inventors: Michel Schneider, Feng Yan, David Lazarus, Jean Brochot, Jerome Puginier
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Publication number: 20050094789Abstract: A method (10, 20) and apparatus (30) enables a customer (47) to distinguish between a dead or broken Internet Protocol telephone line and an out-of-service Internet Protocol telephone line. The method detects (11) a hook status of a device (46) coupled to the IP network (33) during an out-of-service status of the line. Upon detection of a change in state from an on-hook state to an off-hook state, a message is sent (13) to the device (46) indicating that the IP telephone line is currently out-of-service and not dead or broken. This message can be a voice or text message. Moreover, the message can provide status information for all of the interfaces of the device coupled to the IP telephone line. In addition, the message can include information as to how to obtain service, such as a telephone number to call.Type: ApplicationFiled: October 29, 2003Publication date: May 5, 2005Inventor: David Lazarus
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Publication number: 20050030944Abstract: Method and apparatus for adjusting payload header suppression (PHS) at the sender by the receiver based on the receiver's inspection of received packets. As the contents of the packets change, and payload header suppression becomes ineffective, the receiver detects this case and coordinates a switch to an effective payload header suppression rule.Type: ApplicationFiled: May 27, 2003Publication date: February 10, 2005Applicant: General Instrument CorporationInventors: David Lazarus, Beverly Levis
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Publication number: 20030016680Abstract: A Communication Gateway is capable of operating in broadband telephony networks having different Cable Modem Termination System and Call Agent implementations. The Communication Gateway has a set of parameters for use in defining the different implementations. Based on a selected implementation of the different implementations, values for parameters of the set are input into the Communication Gateway. The inputted values are stored. The Communication Gateway operates in the selected implementation using the stored values.Type: ApplicationFiled: July 17, 2001Publication date: January 23, 2003Applicant: General Instrument Corporation, A Delaware CorporationInventors: Robert C. Stein, David Lazarus