Patents by Inventor David Ledden

David Ledden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11040350
    Abstract: Devices, kits, and methods for dispensing at least two liquid reagents for use in analyte(s) detection assays are disclosed.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: June 22, 2021
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventor: David Ledden
  • Publication number: 20210164972
    Abstract: Devices, methods, and kits for detecting at least two analytes present within a small volume single fluid sample obtained from patient for the creation of a multiplexed panel of the various analytes present within the single fluid sample are disclosed.
    Type: Application
    Filed: February 12, 2021
    Publication date: June 3, 2021
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: David Ledden
  • Publication number: 20200200730
    Abstract: A method and a device for determining the concentration of an analyte in whole blood is disclosed. In one embodiment, the method includes generating a plasma layer in the whole blood sample. Furthermore, the method includes exposing the plasma layer to light. The method also includes capturing light reflected from the plasma layer. Additionally, the method includes analyzing the reflected light to determine the concentration of the analyte.
    Type: Application
    Filed: June 7, 2018
    Publication date: June 25, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Satish Kumar Dubey, Ashish Kumar Lal, Vishal Manjanath Prabhu, David Ledden
  • Publication number: 20200140917
    Abstract: Composition(s), device(s), kit(s), and method(s) for an improved analyte detection sensor(s) comprising at least one scavenger protein and method(s) of preserving the functioning and functional life of the improved analyte detection sensor(s).
    Type: Application
    Filed: July 30, 2018
    Publication date: May 7, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Janine Cox, Christopher Lawrence, Murli Narayan, David Ledden
  • Publication number: 20200031889
    Abstract: A fluid sample container comprising a protease, when a sample fluid is placed in the fluid sample container the protease breaking a target analyte in the sample fluid into at least two peptides, the at least two peptides being smaller than the original target analyte.
    Type: Application
    Filed: October 11, 2019
    Publication date: January 30, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: David Ledden, Eric Cowden
  • Patent number: 10472403
    Abstract: A fluid sample container comprising a protease, when a sample fluid is placed in the fluid sample container the protease breaking a target analyte in the sample fluid into at least two peptides, the at least two peptides being smaller than the original target analyte.
    Type: Grant
    Filed: December 23, 2015
    Date of Patent: November 12, 2019
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: David Ledden, Eric Cowden
  • Publication number: 20190331675
    Abstract: Devices, methods, and kits for detecting at least two analytes present within a small volume single fluid sample obtained from patient for the creation of a multiplexed panel of the various analytes present within the single fluid sample are disclosed.
    Type: Application
    Filed: June 6, 2017
    Publication date: October 31, 2019
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: David Ledden
  • Publication number: 20190240667
    Abstract: Devices, kits, and methods for dispensing at least two liquid reagents for use in analyte(s) detection assays are disclosed.
    Type: Application
    Filed: July 6, 2017
    Publication date: August 8, 2019
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: David Ledden
  • Publication number: 20180306815
    Abstract: In one aspect, the inventive concepts disclosed herein are directed to a lateral flow assay comprising: one or more chromatographic substrates, a sample application site, a first capture site, and a second capture site. The first capture site comprising an anti-hCG capture antibody with broad affinity for a group of multiple hCG variants and the second capture site comprising an anti-hCG capture antibody that is specific to a first variant of hCG. Additional aspects of the invention disclose using the later flow assay to determine a ratio of the first variant of hCG to the group of multiple hCG variants.
    Type: Application
    Filed: November 17, 2015
    Publication date: October 25, 2018
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Krastyu Ugrinov, Lloyd Schulman, David Ledden, Janine Cox, Anne Novamo
  • Publication number: 20170369544
    Abstract: A fluid sample container comprising a protease, when a sample fluid is placed in the fluid sample container the protease breaking a target analyte in the sample fluid into at least two peptides, the at least two peptides being smaller than the original target analyte.
    Type: Application
    Filed: December 23, 2015
    Publication date: December 28, 2017
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: David Ledden, Eric Cowden
  • Publication number: 20070278431
    Abstract: Identifying a test product having a test region includes impinging on the test region a set of test signals at known test wavelengths. An image of the test region is generated from the reflected signals. The image is comprised of a set of reflectance values that are compared against reference reflectance values at the test signal wavelengths to determine the test product type.
    Type: Application
    Filed: June 3, 2004
    Publication date: December 6, 2007
    Inventors: David Brock, Chris Zimmerle, David Ledden
  • Publication number: 20070172963
    Abstract: This invention is directed to a lateral flow assay for detecting the presence of an analyte in a liquid test sample. The lateral flow assay represents an improvement in the ability to accurately and with high fidelity to detect the presence or absence of a target analyte in a liquid sample, in part, by encompassing a reference region of immobilized, non-diffusible analyte that allows for detection of any factors that interfere with the interaction and binding of the analyte to the labeled capture reagent. Any influences on the interaction and binding of the analyte that is free in solution in the liquid test sample to its complementary labeled reagent will be encountered in parallel in the binding between the immobilized analyte in reference region to the labeled reagent as it diffuses through the reference region. In one embodiment, the lateral flow assay of the invention is a urine-based human Chorionic Gonadotropin (hCG) assay.
    Type: Application
    Filed: June 3, 2004
    Publication date: July 26, 2007
    Inventors: Gary Krauth, David Ledden
  • Publication number: 20070064220
    Abstract: A readhead for illuminating a sample carrier and receiving light from the sample carrier, including a housing for receiving a sample carrier, an array of light sources mounted within the housing in a fixed position relative to the sample carrier, and including first and second light-emitting diodes for emitting substantially monochromatic light of a two different wavelengths, a light guide mounted in the housing between the light-emitting diodes and the sample carrier, and a light detector coupled to receive light from the sample carrier. The readhead also includes a light source for directing excitation light of a predetermined wavelength to the sample carrier, and a light filter positioned between the sample carrier and the light detector and adapted to prevent passage therethrough of the excitation light. The readhead allows both fluorescence spectroscopy and reflectance spectroscopy to be conducted on the sample carrier.
    Type: Application
    Filed: June 3, 2004
    Publication date: March 22, 2007
    Applicants: BAYER HEALTHCARE LLC., BAYER HEALTHCARE LLC.
    Inventors: Nicholas Stock, Gary Ross, David Ledden