Patents by Inventor David Lehmann

David Lehmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THIAZOLE DERIVATIVES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS
    Publication number: 20130281406
    Abstract: The present invention relates to thiazole derivatives of Formula (I) and their use as P2Y12 receptor antagonists in the treatment and/or prevention of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals.
    Type: Application
    Filed: April 21, 2010
    Publication date: October 24, 2013
    Applicant: Actelion Pharmaceuticals Ltd.
    Inventors: Eva CAROFF, Kurt HILPERT, Francis HUBLER, David LEHMANN, Emmanuel MEYER, Dorte RENNEBERG
  • Airborne biota monitoring and control system
    Patent number: 8400348
    Abstract: Apparatus and methods for an airborne biota monitoring and control system are disclosed. Radar and laser/optical sensors are used to detect insects, with detection zones being over water in some embodiments to reduce backscatter clutter. A pest control laser or small autonomous or radio controlled aircraft under automated or human control may be used to disable a targeted flying insect. One embodiment includes use of a head-mounted display for displaying insect targeting information superimposed on a real landscape view. Technologies such as adaptive lens, holographic optical elements, polarized radar and/or laser beams, light amplifiers and light guides, thin disk, spinning disk, or vertical cavity surface emitting lasers enhance performance of the apparatus or reduce cost of the apparatus. Also disclosed are methods of discrimination of insect types using spectral information and dynamic relative variation of spectral intensities at different wavelengths reflected from an insect in flight.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: March 19, 2013
    Assignee: Applied Information Movement and Management, Inc.
    Inventors: David Lehmann Guice, Augustus Hammond Green, Jr., William Vaden Dent, Jr.
  • Pyridin-3-yl derivatives as immunomodulating agents
    Patent number: 8288554
    Abstract: The invention relates to pyridin-3-yl derivatives of Formula (I) wherein R1, R2, R3, R4, R5; R6 and A are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Grant
    Filed: September 6, 2007
    Date of Patent: October 16, 2012
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jörg Velker
  • NOVEL PYRIDINE DERIVATIVES
    Publication number: 20120195930
    Abstract: The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: April 3, 2012
    Publication date: August 2, 2012
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jörg Velker
  • Pyridine derivatives
    Patent number: 8178562
    Abstract: The invention relates to novel pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: May 15, 2012
    Assignee: Actelion Pharmaceuticals, Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Joerg Velker
  • Thiophene derivatives as S1P1/EDGE1 receptor agonists
    Patent number: 8133910
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: March 13, 2012
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jörg Velker
  • THIAZOLE DERIVATIVES AND THEIR USE AS P2Y12 RECEPTOR ANTAGONISTS
    Publication number: 20120053149
    Abstract: The present invention relates to thiazole derivatives of formula I and their use as P2Y12 receptor antagonists in the treatment and/or prevention of peripheral vascular, of visceral-, hepatic- and renal-vascular, of cardiovascular and of cerebrovascular diseases or conditions associated with platelet aggregation, including thrombosis in humans and other mammals.
    Type: Application
    Filed: April 21, 2010
    Publication date: March 1, 2012
    Inventors: Eva Caroff, Kurt Hilpert, Francis Hubler, David Lehmann, Emmanuel Meyer, Dorte Renneberg
  • Composition and method for cell permeabilization comprising N-octyl-?-D-glucopyranoside, sodium polyphosphates, rubidium chloride and/or lithium chloride for detecting living cells on a membrane
    Patent number: 8097404
    Abstract: The present invention relates to a composition for the permeabilization of the walls of microorganisms comprising the combination of octyl-?-D-glucopyranoside (NOG), sodium polyphosphates (HMP), and a salt chosen from lithium chloride or rubidium chloride, and a method for the enumeration and identification of cells on a membrane using said composition.
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: January 17, 2012
    Assignee: Millipore Corporation
    Inventors: Sebastien Ribault, Frederic Olivieri, Herve Meder, David Lehmann, Sandra Laborde
  • Phenyl derivatives and their use as immunomodulators
    Patent number: 8044076
    Abstract: The invention relates to phenyl derivatives of formula (I), their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: October 25, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jorg Velker
  • Hydrogenated benzo (C) thiophene derivatives as immunomodulators
    Patent number: 8039644
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: October 18, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jorg Velker, Thomas Weller
  • Thiophene derivatives as S1P1/EDG1 receptor agonists
    Patent number: 8003800
    Abstract: The invention relates to thiophene derivatives of formula (I)/their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents wherein: A represents *—CO—CH?CH—, *—CO—CH2CH2—, *—CO—CH2—NH—, wherein the asterisks indicate the bond that is linked to the thiophene group of Formula (I), and R1-R3 are as defined in the claims.
    Type: Grant
    Filed: January 10, 2007
    Date of Patent: August 23, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jörg Velker
  • Thiophene derivatives
    Patent number: 7981924
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: July 19, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jörg Velker
  • Thiophene derivatives
    Patent number: 7951794
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: June 20, 2006
    Date of Patent: May 31, 2011
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Jörg Velker
  • METHOD FOR CREATING NUMERICAL CONTROL PROGRAMS
    Publication number: 20110046766
    Abstract: A method for creating an NC program for controlling a test run for determining, optimizing and/or validating processing parameters and/or control parameters of a processing operation on a laser processing machine comprises accessing a base NC program that includes at least one contour variable for the at least one test contour to be produced in the test run and at least one decision function for value assignment of a contour parameter to the contour variable, providing a selection function for selection by an operator of a combination of input values that are characteristic of the processing operation, and creating the NC program from the base NC program by automatic execution of the at least one decision function for assigning a contour parameter to the contour variable, the contour parameter being determined based on the combination of input values.
    Type: Application
    Filed: September 23, 2010
    Publication date: February 24, 2011
    Applicant: TRUMPF MASCHINEN GRUESCH AG
    Inventors: Uwe Mienhardt, David Lehmann
  • Thiophene derivatives as spingosine-1-phosphate-1 receptor agonists
    Patent number: 7846964
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: December 7, 2010
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, J{umlaut over ())}{umlaut over (})}org Velker, Thomas Weller
  • NOVEL THIOPHENE DERIVATIVES AS S1P1/EDG1 RECEPTOR AGONISTS
    Publication number: 20100240717
    Abstract: The invention relates to thiophene derivatives of formula (I)/their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents wherein: A represents *—CO—CH?CH—, *—CO—CH2CH2—, *—CO—CH2—NH—, wherein the sterisks indicate the bond that is linked to the thiophene group of Formula (I), and R1-R3 are as defined in the claims.
    Type: Application
    Filed: January 10, 2007
    Publication date: September 23, 2010
    Applicant: ACTELION PHARMACEUTICALS LTD.
    Inventors: Martin Boli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner, Jörg Velker
  • HYDROGENATED BENZO (C) THIOPHENE DERIVATIVES AS IMMUNOMODULATORS
    Publication number: 20100204198
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Application
    Filed: March 29, 2010
    Publication date: August 12, 2010
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jörg Velker, Thomas Weller
  • Thiophene derivatives
    Patent number: 7750040
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents.
    Type: Grant
    Filed: July 20, 2005
    Date of Patent: July 6, 2010
    Inventors: Martin Bolli, Daniel Bur, Martine Clozel, Walter Fischli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Michael Scherz, Thomas Weller
  • Pyridin-3-yl derivatives as immunomodulating agents
    Publication number: 20100168005
    Abstract: The invention relates to pyridin-3-yl derivatives of Formula (I) wherein R1, R2, R3, R4, R5; R6 and A are as described in the description, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents.
    Type: Application
    Filed: September 6, 2007
    Publication date: July 1, 2010
    Applicant: ACTELION PHARMACEUTICALS LTD.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Beat Steiner
  • Hydrogenated benzo (C) thiophene derivatives as immunomodulators
    Patent number: 7723378
    Abstract: The invention relates to novel thiophene derivatives, their preparation and their use as pharmaceutically active compounds particularly as immunosuppressant agents.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: May 25, 2010
    Assignee: Actelion Pharmaceuticals Ltd.
    Inventors: Martin Bolli, David Lehmann, Boris Mathys, Claus Mueller, Oliver Nayler, Jörg Velker, Thomas Weller